Zobrazeno 1 - 10
of 88
pro vyhledávání: '"José A. Sánchez-Chapula"'
Autor:
Daniela Ponce-Balbuena, Eloy G. Moreno-Galindo, Angélica López-Izquierdo, Tania Ferrer, José A. Sánchez-Chapula
Publikováno v:
Journal of Pharmacological Sciences, Vol 113, Iss 1, Pp 66-75 (2010)
Tamoxifen inhibits transmembrane currents of the Kir2.x inward rectifier potassium channels by interfering with the interaction of the channels with membrane phosphatidylinositol 4,5-bisphosphate (PIP2). We tested the hypothesis that Kir channels wit
Externí odkaz:
https://doaj.org/article/b79a4a2e95024af99502c5c0d9e45438
Autor:
Iván A. Aréchiga, Gabriel F. Barrio-Echavarria, Aldo A. Rodríguez-Menchaca, Eloy G. Moreno-Galindo, Niels Decher, Martin Tristani-Firouzi, José A. Sánchez-Chapula, Ricardo A. Navarro-Polanco
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 1, Pp 49-55 (2008)
Kv1.5 is considered to be a potential molecular target for treatment of atrial fibrillation or flutter. Disopyramide is widely used in the treatment of atrial flutter and/or atrial fibrillation. The present study was undertaken to characterize the ef
Externí odkaz:
https://doaj.org/article/ead7d2eb701d42ad956e37d6f374ed81
Autor:
Aldo A. Rodríguez-Menchaca, Fanny Junue Rodriguez-Leal, Eloy G. Moreno-Galindo, Mayra Delgado-Ramírez, Tania Ferrer, José A. Sánchez-Chapula
Publikováno v:
Acta Pharmaceutica
Volume 71
Issue 2
Acta Pharmaceutica, Vol 71, Iss 2, Pp 317-324 (2021)
Volume 71
Issue 2
Acta Pharmaceutica, Vol 71, Iss 2, Pp 317-324 (2021)
Terfenadine is a second-generation H1-antihistamine that despite potentially can produce severe side effects it has recently gained attention due to its anticancer properties. Lately, the subfamily 2 of inward rectifier potassium channels (Kir2) has
Autor:
David O. Pacheco-Rojas, Eloy G. Moreno-Galindo, José A. Sánchez-Chapula, Mayra Delgado-Ramírez, Tania Ferrer, Aldo A. Rodríguez-Menchaca, Kathya Villatoro-Gómez
Publikováno v:
European journal of pharmacology. 899
Riluzole is an anticonvulsant drug also used to treat the amyotrophic lateral sclerosis and major depressive disorder. This compound has antiglutamatergic activity and is an important multichannel blocker. However, little is known about its actions o
Differential voltage-dependent modulation of the ACh-gated K+ current by adenosine and acetylcholine
Autor:
Ana Laura López-Serrano, Rodrigo Zamora-Cárdenas, Iván A. Aréchiga-Figueroa, Pedro D. Salazar-Fajardo, Tania Ferrer, Javier Alamilla, José A. Sánchez-Chapula, Ricardo A. Navarro-Polanco, Eloy G. Moreno-Galindo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0261960 (2022)
PLoS ONE, Vol 17, Iss 1, p e0261960 (2022)
Inhibitory regulation of the heart is determined by both cholinergic M2 receptors (M2R) and adenosine A1 receptors (A1R) that activate the same signaling pathway, the ACh-gated inward rectifier K+ (KACh) channels via Gi/o proteins. Previously, we hav
Autor:
Ana Laura López-Serrano, Martin Tristani-Firouzi, Eloy G. Moreno-Galindo, Javier Alamilla, Iván A. Aréchiga-Figueroa, Julio C. Rodríguez-Elías, José A. Sánchez-Chapula, Ricardo A. Navarro-Polanco, Pedro D. Salazar-Fajardo
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 470:1765-1776
The acetylcholine (ACh)-gated inwardly rectifying K+ current (IKACh) plays a vital role in cardiac excitability by regulating heart rate variability and vulnerability to atrial arrhythmias. These crucial physiological contributions are determined pri
Autor:
José A. Sánchez-Chapula, Ricardo A. Navarro-Polanco, Meng Cui, David O. Pacheco-Rojas, Eloy G. Moreno-Galindo, Tania Ferrer, Kathya Villatoro-Gómez, Dimitris Gazgalis, Martin Tristani-Firouzi
Publikováno v:
Biochemical Pharmacology. 152:264-271
Amitriptyline (AMIT) is a compound widely prescribed for psychiatric and non-psychiatric conditions including depression, migraine, chronic pain, and anorexia. However, AMIT has been associated with risks of cardiac arrhythmia and sudden death since
Autor:
Tania Ferrer, Eloy G. Moreno-Galindo, Ricardo A. Navarro-Polanco, Leticia G. Marmolejo-Murillo, Meng Cui, Iván A. Aréchiga-Figueroa, José A. Sánchez-Chapula, Aldo A. Rodríguez-Menchaca
Publikováno v:
European Journal of Pharmacology. 800:40-47
Kir4.1 channels have been implicated in various physiological processes, mainly in the K + homeostasis of the central nervous system and in the control of glial function and neuronal excitability. Even though, pharmacological research of these channe
Autor:
Aintzane Alday, José A. Sánchez-Chapula, Iván A. Aréchiga-Figueroa, L Layse Malagueta-Vieira, Janire Urrutia, Oscar Casis, Mónica Gallego
Publikováno v:
Cellular Physiology and Biochemistry, Vol 40, Iss 6, Pp 1261-1273 (2016)
Background: The rapid delayed rectifier K+ current (IKr), carried by the hERG protein, is one of the main repolarising currents in the human heart and a reduction of this current increases the risk of ventricular fibrillation. α1-adrenoceptors (α1-
Autor:
Javier Alamilla, Eloy G. Moreno-Galindo, Ricardo A. Navarro-Polanco, Martin Tristani-Firouzi, José A. Sánchez-Chapula
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 468:1207-1214
Recently, it has been shown that G protein-coupled receptors (GPCRs) display intrinsic voltage sensitivity. We reported that the voltage sensitivity of M2 muscarinic receptor (M2R) is also ligand specific. Here, we provide additional evidence to unde