Zobrazeno 1 - 10
of 364
pro vyhledávání: '"José A. Pérez Simón"'
Autor:
David Martínez-Cuadrón, Juan E. Megías-Vericat, Cristina Gil, Teresa Bernal, Mar Tormo, Pilar Martínez-Sánchez, Carlos Rodríguez-Medina, Josefina Serrano, Pilar Herrera, José A. Pérez Simón, María J. Sayas, Juan Bergua, Esperanza Lavilla-Rubira, Maria Luz Amigo, Celina Benavente, Jose L. López Lorenzo, Manuel M. Pérez-Encinas, María B. Vidriales, Mercedes Colorado, Beatriz de Rueda, Raimundo García-Boyero, Sandra Marini, Julio García-Suárez, María López-Pavía, Maria I. Gómez-Roncero, Víctor Noriega, Aurelio López, Jorge Labrador, Ana Cabello, Claudia Sossa, Lorenzo Algarra, Mariana Stevenazzi, Antonio Solana-Altabella, Blanca Boluda, Pau Montesinos
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Treatment options for patients with secondary acute myeloid leukemia (sAML) and AML with myeloid-related changes (AMLMRC) aged 60 to 75 years are scarce and unsuitable. A pivotal trial showed that CPX-351 improved complete remission with/without inco
Externí odkaz:
https://doaj.org/article/f978279b26d241eca282876eec8ca76b
Autor:
Claudia Sargas, Rosa Ayala, María J. Larráyoz, María C. Chillón, Eduardo Rodriguez-Arboli, Cristina Bilbao, Esther Prados de la Torre, David Martínez-Cuadrón, Rebeca Rodríguez-Veiga, Blanca Boluda, Cristina Gil, Teresa Bernal, Juan Bergua, Lorenzo Algarra, Mar Tormo, Pilar Martínez-Sánchez, Elena Soria, Josefina Serrano, Juan M. Alonso-Dominguez, Raimundo García, María Luz Amigo, Pilar Herrera-Puente, María J. Sayas, Esperanza Lavilla-Rubira, Joaquín Martínez-López, María J. Calasanz, Ramón García-Sanz, José A. Pérez-Simón, María T. Gómez Casares, Joaquín Sánchez-García, Eva Barragán, Pau Montesinos, PETHEMA cooperative study group
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Next-Generation Sequencing is needed for the accurate genetic risk stratification of acute myeloid leukemia according to European LeukemiaNet (ELN) guidelines. We validated and compared the 2022 ELN risk classification in a real-life cohort
Externí odkaz:
https://doaj.org/article/922c45afad2e435b8c679c0aca4ae8f0
Autor:
Clara Beatriz García-Calderón, Belén Sierro-Martínez, Estefanía García-Guerrero, Luzalba Sanoja-Flores, Raquel Muñoz-García, Victoria Ruiz-Maldonado, María Reyes Jimenez-Leon, Javier Delgado-Serrano, Águeda Molinos-Quintana, Beatriz Guijarro-Albaladejo, Inmaculada Carrasco-Brocal, José-Manuel Lucena, José-Raúl García-Lozano, Cristina Blázquez-Goñi, Juan Luis Reguera-Ortega, María-Francisca González-Escribano, Marta Reinoso-Segura, Javier Briones, José Antonio Pérez-Simón, Teresa Caballero-Velázquez
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
PurposeCAR-T cell therapy has proven to be a disruptive treatment in the hematology field, however, less than 50% of patients maintain long-term response and early predictors of outcome are still inconsistently defined. Here, we aimed to optimize the
Externí odkaz:
https://doaj.org/article/e96a06555ede4b65b1cb1ecb9861c04c
Autor:
Maria-Luisa del Rio, Carla Yago-Diez de Juan, Giovanna Roncador, Eduardo Caleiras, Ramón Álvarez-Esteban, José Antonio Pérez-Simón, Jose-Ignacio Rodriguez-Barbosa
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionA high frequency of mutations affecting the gene encoding Herpes Virus Entry Mediator (HVEM, TNFRSF14) is a common clinical finding in a wide variety of human tumors, including those of hematological origin.MethodsWe have addressed how HV
Externí odkaz:
https://doaj.org/article/d45f1aac1da2426b84b5c0a30178393d
Autor:
Alfonso Rodríguez-Gil, Virginia Escamilla-Gómez, Melanie Nufer, Félix Andújar-Sánchez, Teresa Lopes-Ramos, José Antonio Bejarano-García, Estefanía García-Guerrero, Cristina Calderón-Cabrera, Teresa Caballero-Velázquez, Clara Beatriz García-Calderón, Paola Hernández-Díaz, Juan Luis Reguera-Ortega, Nancy Rodríguez-Torres, Nuria Martínez-Cibrián, José Ignacio Rodríguez-Barbosa, Javier Villadiego, José Antonio Pérez-Simón
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Donor derived regulatory T lymphocytes and the JAK1/2 kinase inhibitor ruxolitinib are currently being evaluated as therapeutic options in the treatment of chronic graft versus host disease (cGvHD). In this work, we aimed to determine if the
Externí odkaz:
https://doaj.org/article/3db0b7b937be458e9028eb37c76620a7
Autor:
Claire Fielding, Andrés García-García, Claudia Korn, Stephen Gadomski, Zijian Fang, Juan L. Reguera, José A. Pérez-Simón, Berthold Göttgens, Simón Méndez-Ferrer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The sympathetic nervous system has been shown to respond to stress and activate haematopoietic stem cells. Here they show that cholinergic signals in the bone marrow preserve haematopoietic stem cell quiescence and self-renewal under proliferative st
Externí odkaz:
https://doaj.org/article/a37b394503a547f08085bab8d2e09c03
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/bde63dd1577541dbbbe4df94ed41744c
Autor:
Concepción Prats‐Martín, Sergio Burillo‐Sanz, Rosario M. Morales‐Camacho, Olga Pérez‐López, Milagros Suito, Maria T. Vargas, Teresa Caballero‐Velázquez, Estrella Carrillo‐Cruz, José González, Ricardo Bernal, José A. Pérez‐Simón
Publikováno v:
Cancer Medicine, Vol 9, Iss 11, Pp 3637-3646 (2020)
Abstract Acute myeloid leukemia with myelodysplasia‐related changes (AML‐MRC) are poor outcome leukemias. Its diagnosis is based on clinical, cytogenetic, and cytomorphologic criteria, last criterion being sometimes difficult to assess. A high fr
Externí odkaz:
https://doaj.org/article/f43c49145b2a442d9b8b572ba497bc8a
Autor:
Alfonso Rodríguez-Gil, Estrella Carrillo-Cruz, Cristina Marrero-Cepeda, Guillermo Rodríguez, José A. Pérez-Simón
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 987 (2022)
The different cell subsets of the immune system express the vitamin D receptor (VDR). Through the VDR, vitamin D exerts different functions that influence immune responses, as previously shown in different preclinical models. Based on this background
Externí odkaz:
https://doaj.org/article/b540fa6bde274388b4c733e6809dc449
Autor:
Jake Shortt, Pau Montesinos, Shuh Ying Tan, Teng Fong Ng, Chun Yew Fong, Paul Cannell, Rajeev Rajagopal, Sophia Leitch, Peter T. Tan, Sundra Ramanathan, Robin Gasiorowski, Douglas Stuart Lenton, Tse-Chieh Teh, José Antonio Pérez-Simón, Carolyn Grove, Xiaojun Huang, Courtney D. DiNardo, Katherine Naidu, Joseph Pariseau, Si Cheng, Yu Liu, Melannie Co, Wai Y. Chan, Haiyi Guo, Andrew H. Wei
Publikováno v:
Blood. 140:3329-3332