Zobrazeno 1 - 9
of 9
pro vyhledávání: '"José A. Martinez-Climent"'
Autor:
Inga Nieländer, José I. Martín-Subero, Florian Wagner, Michael Baudis, Stefan Gesk, Lana Harder, Dirk Hasenclever, Wolfram Klapper, Markus Kreuz, Christiane Pott, José A. Martinez-Climent, Martin Dreyling, Norbert Arnold, Reiner Siebert
Publikováno v:
Haematologica, Vol 93, Iss 6 (2008)
Externí odkaz:
https://doaj.org/article/94fa457b07b1465d8dde027c1e9745d6
Autor:
Patricia Pérez-Galán, Javier Melchor, Marcos Garcia-Lacarte, Sara C. Grijalba, Adrián Arnaiz-Leché, Marién Pascual, Carlos Panizo, Oscar Blanco, Victor Segura, Francisco J. Novo, Juan Garcia Valero, Jose A. Martinez-Climent, Sergio Roa
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background Approximately one-third of diffuse large B cell lymphoma (DLBCL) patients exhibit co-expression of MYC and BCL2 (double-expressor lymphoma, DEL) and have a dismal prognosis. Targeted inhibition of the anti-apoptotic protein BCL2 with venet
Externí odkaz:
https://doaj.org/article/47edd513890f4a44a88ecef8b5131142
Autor:
José I, Martín-Subero, Lana, Harder, Stefan, Gesk, Brigitte, Schlegelberger, Werner, Grote, José A, Martinez-Climent, Martin J S, Dyer, Francisco J, Novo, María J, Calasanz, Reiner, Siebert
Publikováno v:
International journal of cancer. 98(3)
Many B-cell malignancies bear chromosomal translocations juxtaposing immunoglobulin (IG) genes with oncogenes, resulting in deregulated expression of the latter. Translocations affecting the IG heavy chain (IGH) locus in chromosomal region 14q32 are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2002bb6e2420c510f7d7cf1c87ac17ba
https://pubmed.ncbi.nlm.nih.gov/11920602
https://pubmed.ncbi.nlm.nih.gov/11920602
Autor:
Naiara Martínez-Vélez, Marc Garcia-Moure, Miguel Marigil, Marisol González-Huarriz, Montse Puigdelloses, Jaime Gallego Pérez-Larraya, Marta Zalacaín, Lucía Marrodán, Maider Varela-Guruceaga, Virginia Laspidea, Jose Javier Aristu, Luis Isaac Ramos, Sonia Tejada-Solís, Ricardo Díez-Valle, Chris Jones, Alan Mackay, Jose A. Martínez-Climent, Maria Jose García-Barchino, Eric Raabe, Michelle Monje, Oren J. Becher, Marie Pierre Junier, Elias A. El-Habr, Herve Chneiweiss, Guillermo Aldave, Hong Jiang, Juan Fueyo, Ana Patiño-García, Candelaria Gomez-Manzano, Marta M. Alonso
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The oncolytic virus Delta-24-RGD is in clinical trial for adult glioma. Here, the authors show that this virus elicits an immune response in mouse models of pediatric high-grade glioma and diffuse pontine intrinsic glioma, resulting in improved survi
Externí odkaz:
https://doaj.org/article/e70b68b3d2c14bafb5f5185c1fba26c6
Autor:
Eloy F. Robles, Maria Mena-Varas, Laura Barrio, Sara V. Merino-Cortes, Péter Balogh, Ming-Qing Du, Takashi Akasaka, Anton Parker, Sergio Roa, Carlos Panizo, Idoia Martin-Guerrero, Reiner Siebert, Victor Segura, Xabier Agirre, Laura Macri-Pellizeri, Beatriz Aldaz, Amaia Vilas-Zornoza, Shaowei Zhang, Sarah Moody, Maria Jose Calasanz, Thomas Tousseyn, Cyril Broccardo, Pierre Brousset, Elena Campos-Sanchez, Cesar Cobaleda, Isidro Sanchez-Garcia, Jose Luis Fernandez-Luna, Ricardo Garcia-Muñoz, Esther Pena, Beatriz Bellosillo, Antonio Salar, Maria Joao Baptista, Jesús Maria Hernandez-Rivas, Marcos Gonzalez, Maria Jose Terol, Joan Climent, Antonio Ferrandez, Xavier Sagaert, Ari M. Melnick, Felipe Prosper, David G. Oscier, Yolanda R. Carrasco, Martin J. S. Dyer, Jose A. Martinez-Climent
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
The homeobox NKX2 family of transcriptional factors has been shown to regulate fundamental developmental processes. Here, the authors show that NKX2-3 is a bona fideoncogenic driver in marginal-zone B-cell lymphoma and that it promotes lymphomagenesi
Externí odkaz:
https://doaj.org/article/8577d51efbf14e6384756140937ba872
Autor:
Francesca Rapino, Eloy F. Robles, Jose A. Richter-Larrea, Eric M. Kallin, Jose A. Martinez-Climent, Thomas Graf
Publikováno v:
Cell Reports, Vol 3, Iss 4, Pp 1153-1163 (2013)
Earlier work demonstrated that the transcription factor C/EBPα can convert immature and mature murine B lineage cells into functional macrophages. Testing >20 human lymphoma and leukemia B cell lines, we found that most can be transdifferentiated at
Externí odkaz:
https://doaj.org/article/ebef9f95d9b541daab913c4c1d5ee4cf
Autor:
Francesca Rapino, Eloy F. Robles, Jose A. Richter-Larrea, Eric M. Kallin, Jose A. Martinez-Climent, Thomas Graf
Publikováno v:
Cell Reports, Vol 19, Iss 6, p 1281 (2017)
Externí odkaz:
https://doaj.org/article/63f4a2615d3b4f398a0b464634493f4b
Autor:
Raquel Malumbres, Vicente Fresquet, Jose Roman-Gomez, Miriam Bobadilla, Eloy F. Robles, Giovanna G. Altobelli, M.ª José Calasanz, Erlend B. Smeland, Maria Angela Aznar, Xabier Agirre, Vanesa Martin-Palanco, Felipe Prosper, Izidore S. Lossos, Jose A. Martinez-Climent
Publikováno v:
Haematologica, Vol 96, Iss 7 (2011)
Background LMO2 is highly expressed at the most immature stages of lymphopoiesis. In T-lymphocytes, aberrant LMO2 expression beyond those stages leads to T-cell acute lymphoblastic leukemia, while in B cells LMO2 is also expressed in germinal center
Externí odkaz:
https://doaj.org/article/5617bccc3c094e54a13ca3cdccc7b302
Publikováno v:
Haematologica, Vol 95, Iss 2 (2010)
While leukemia-originating stem cells are critical in the initiation and maintenance of leukemias, the existence of similar cell populations that may generate B-cell lymphoma upon mutation remains uncertain. Here we propose that committed lymphoid pr
Externí odkaz:
https://doaj.org/article/4404e6686af54ab884f2692dee1f9623