Zobrazeno 1 - 10
of 62
pro vyhledávání: '"José A. Guevara-Patiño"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/f513b1f1dfcb423898e41bf99cc5fd26
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Vitiligo is an acquired multifactorial disease that affects melanocytes and results in skin depigmentation. In this review, we examine the role of cells stress and self-reactive T cells responses. Given the canonical and non-canonical functions of NK
Externí odkaz:
https://doaj.org/article/337cc95d723a4738bdfd0b3616d92329
Autor:
Frederick J. Kohlhapp, Jeremy A. O’Sullivan, Tamson V. Moore, Andrew Zloza, José A. Guevara-Patiño
Publikováno v:
Mol Immunol
CD8 T cells play a critical role in immunity against intracellular pathogens and cancer. A primary objective of T cell-based vaccine strategies is the induction of durable and effective immune responses. Achieving this goal involves more than simply
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bfda013de95e8285ce0bce7acacad2
https://europepmc.org/articles/PMC9992161/
https://europepmc.org/articles/PMC9992161/
Autor:
Alex Gorbonos, Lourdes Beatriz Plaza Rojas, Elizabeth L. Koehne, Hiten D. Patel, Michael Woods, Nicholas Elliott, José A. Guevara-Patiño, Alex Belshoff, Marcus L. Quek, Gopal N. Gupta, Michael Delos Reyes
Publikováno v:
Journal of Urology. 206
INTRODUCTION AND OBJECTIVE:Checkpoint inhibitors (CPI) have emerged as a way to activate the immune system’s antitumor properties by blocking inhibitory signals such as programmed cell death ligand...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::105965ece350efdb5441b2c3ef1e8b5d
https://doi.org/10.1097/ju.0000000000002106.16
https://doi.org/10.1097/ju.0000000000002106.16
Autor:
José A. Guevara-Patiño, I. Caroline Le Poole, Manuel F. Fernandez, Richard Duff, Andrew L. Salzman, Steven W. Henning, James P. Mahon, Alfred Rademaker, Farshid Azarafrooz
Publikováno v:
Journal of Investigative Dermatology. 138:2531-2539
Human HSP70iQ435A carries a single amino-acid modification within the dendritic cell activating region and tolerizes dendritic cells in vitro. The underlying DNA was used to prevent and treat disease in vitiligo mouse models through reduced dendritic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f06fc7d5a66145a85838a74bb04c7c84
https://doi.org/10.1016/j.jid.2018.06.186
https://doi.org/10.1016/j.jid.2018.06.186
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Vitiligo is an acquired multifactorial disease that affects melanocytes and results in skin depigmentation. In this review, we examine the role of cells stress and self-reactive T cells responses. Given the canonical and non-canonical functions of NK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fb962c0be94cfcb32e86ac990d4f7c
http://europepmc.org/articles/PMC7952755
http://europepmc.org/articles/PMC7952755
Autor:
Dinesh, Jaishankar, Cormac, Cosgrove, Prathyaya, Ramesh, James, Mahon, Rohan, Shivde, Emilia R, Dellacecca, Shiayin F, Yang, Jeffrey, Mosenson, José A, Guevara-Patiño, I Caroline, Le Poole
Publikováno v:
Cell Stress Chaperones
Developing immunosuppressive therapies for autoimmune diseases comes with a caveat that immunosuppression may promote the risk of developing other conditions or diseases. We have previously shown that biolistic delivery of an expression construct enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8a9b21e9d9e99f32073e12130f47a76
https://pubmed.ncbi.nlm.nih.gov/34542825
https://pubmed.ncbi.nlm.nih.gov/34542825
Publikováno v:
The Journal of investigative dermatology. 140(6)
In the study by Jacquemin et al., the authors reported that ligands for NKG2D are upregulated in vitiligo perilesional skin and especially in patients with active disease. The reasons for the elevated expression of NKG2D ligands are unknown. This stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287fe9db0f981db59a80ebc6a53306ae
https://pubmed.ncbi.nlm.nih.gov/31877315
https://pubmed.ncbi.nlm.nih.gov/31877315
Autor:
Michael Delos Reyes, Lourdes Plaza-Rojas, Kushal Prajapati, Brianna Burke, Cynthia Perez, Phong T. Le, Shubin Zhang, José A. Guevara-Patiño
Publikováno v:
SSRN Electronic Journal.
Few costimulatory molecules have been shown to deeply impact the development and function of CD8 T cells. To our knowledge, only CD28, the archetype of TCR co-stimulation, has been reported to affect thymic T cell development. The role of NKG2D in pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e57b9082998acfc4725ce8820dd16d14
https://doi.org/10.2139/ssrn.3614122
https://doi.org/10.2139/ssrn.3614122
Autor:
Elizabeth Henry, Alex Belshoff, Gopal N. Gupta, Cynthia Perez, Kushal Prajapati, Brianna Burke, Lourdes Plaza-Rojas, Catherine Eden, Michael Delos Reyes, Christina Voelkel-Johnson, José A. Guevara-Patiño, Spencer Hart
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology, Vol 10 (2020)
Inhibitory checkpoint blockade therapy is an immunomodulatory strategy that results in the restoration of T cell functions, and its efficacy depends on the recognition of tumor cells for destruction. Considering the factors at play, one could propose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56002cb04b3c3b6c802ff10dcd2de94
https://pubmed.ncbi.nlm.nih.gov/32500025
https://pubmed.ncbi.nlm.nih.gov/32500025