Zobrazeno 1 - 10
of 22
pro vyhledávání: '"José A. Guerrero-Martínez"'
Autor:
Salvador Polo-Generelo, Cristina Rodríguez-Mateo, Belén Torres, José Pintor-Tortolero, José A. Guerrero-Martínez, Julian König, Jesús Vázquez, Elena Bonzón-Kulichenco, Javier Padillo-Ruiz, Fernando de la Portilla, José C. Reyes, José A. Pintor-Toro
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Serine protease inhibitor clade E member 1 (SERPINE1) inhibits extracellular matrix proteolysis and cell detachment. However, SERPINE1 expression also promotes tumor progression and plays a crucial role in metastasis. Here, we solve this app
Externí odkaz:
https://doaj.org/article/629415ade15d4c34af8608ba5ab13e55
Autor:
Laura Basurto-Cayuela, José A. Guerrero-Martínez, Elena Gómez-Marín, Elena Sánchez-Escabias, María Escaño-Maestre, María Ceballos-Chávez, José C. Reyes
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113855- (2024)
Summary: SWI/SNF complexes are evolutionarily conserved, ATP-dependent chromatin remodeling machines. Here, we characterize the features of SWI/SNF-dependent genes using BRM014, an inhibitor of the ATPase activity of the complexes. We find that SWI/S
Externí odkaz:
https://doaj.org/article/e26ac248304f42cba1f5c27ce34cd34f
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Co-transcriptional splicing efficiency is a gene-specific characteristic that can be regulated by TGFβ to modulate gene expression.
Externí odkaz:
https://doaj.org/article/1be7c9d855c4488f82da482416502d9c
Autor:
Salvador Polo-Generelo, Belén Torres, José A. Guerrero-Martínez, Emilio Camafeita, Jesús Vázquez, José C. Reyes, José A. Pintor-Toro
Publikováno v:
Non-Coding RNA, Vol 8, Iss 5, p 62 (2022)
Long non-coding RNAs (lncRNAs) have emerged as key regulators in a wide range of biological processes. Here, we identified a mouse miRNA-host gene lncRNA (Lnc-Nr6a1) upregulated early during epithelial-to-mesenchymal transition (EMT). We show that wh
Externí odkaz:
https://doaj.org/article/418910a5da05480d8a9fe6090e7b9ef5
Autor:
Elena Gómez-Marín, Melanija Posavec-Marjanović, Laura Zarzuela, Laura Basurto-Cayuela, José A Guerrero-Martínez, Gonzalo Arribas, Rosario Yerbes, María Ceballos-Chávez, Manuel Rodríguez-Paredes, Mercedes Tomé, Raúl V Durán, Marcus Buschbeck, José C Reyes
Publikováno v:
Nucleic Acids Research. 50:9838-9857
High mobility group (HMG) proteins are chromatin regulators with essential functions in development, cell differentiation and cell proliferation. The protein HMG20A is predicted by the AlphaFold2 software to contain three distinct structural elements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9ecd6c96d7adaa0fa9313e24ee7d2b
https://doi.org/10.1093/nar/gkac766
https://doi.org/10.1093/nar/gkac766
Autor:
Salvador, Polo-Generelo, Belén, Torres, José A, Guerrero-Martínez, Emilio, Camafeita, Jesús, Vázquez, José C, Reyes, José A, Pintor-Toro
Publikováno v:
Non-coding RNA. 8(5)
Long non-coding RNAs (lncRNAs) have emerged as key regulators in a wide range of biological processes. Here, we identified a mouse miRNA-host gene lncRNA (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9665b6dae8a6946263f4abadf5c3900e
https://pubmed.ncbi.nlm.nih.gov/36136852
https://pubmed.ncbi.nlm.nih.gov/36136852
Autor:
Laura Payán-Bravo, Esther Lara, Sara Fontalva, Yosu Odriozola-Gil, Sebastián Chávez, Silvia Jimeno-González, Ildefonso Cases, Carles Suñé, Yerma Pareja-Sanchez, José Antonio Guerrero-Martínez, Xenia Peñate, Jose C. Reyes, Mari Cruz Muñoz-Centeno
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nucleic Acids Research
instname
Digital.CSIC. Repositorio Institucional del CSIC
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nucleic Acids Research
Prefoldin is a heterohexameric complex conserved from archaea to humans that plays a cochaperone role during the co-translational folding of actin and tubulin monomers. Additional functions of prefoldin have been described, including a positive contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca2dd77cba67057550c36122010a247
http://hdl.handle.net/10261/309906
http://hdl.handle.net/10261/309906
Autor:
Antonio Campos-Caro, Eduardo García Fuentes, Francisco Javier Bermúdez-Silva, Nadia Cobo-Vuilleumier, Petra I. Lorenzo, Christian Claude Lachaud, Benoit R. Gauthier, Valentine Comaills, Esther Fuente-Martin, Jose C. Reyes, Alejandro Martin-Montalvo, Alejandra Crespo Barreda, José A Guerrero Martínez, Sabrina Rivero Canalejo, Jesús Ángel Pérez-Cabello, Franz Martín, Manuel Álvarez Dolado, José Manuel Mellado-Gil, Eugenia Martin Vázquez, Gemma Rojo-Martínez, Silvana Y. Romero-Zerbo, David Pozo, Jaime M. Franco, Manuel Aguilar-Diosdado, Livia López-Noriega
Publikováno v:
Theranostics
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Rationale: We recently demonstrated that the Metabesity factor HMG20A regulates islet beta-cell functional maturity and adaptation to physiological stress such as pregnancy and pre-diabetes. HMG20A also dictates central nervous system (CNS) developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353d6c4b8b7acf4f3e6f9f951fd6d22d
https://doi.org/10.7150/thno.57237
https://doi.org/10.7150/thno.57237
Publikováno v:
Communications biology. 5(1)
Differential splicing efficiency of specific introns is a mechanism that dramatically increases protein diversity, based on selection of alternative exons for the final mature mRNA. However, it is unclear whether splicing efficiency of introns within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::891a3c27517c5e7ebee88887b3992fcc
https://pubmed.ncbi.nlm.nih.gov/35347226
https://pubmed.ncbi.nlm.nih.gov/35347226
Autor:
Florian Koehler, Sandra Peiró, María Ceballos-Chávez, José C. Reyes, José A. Guerrero-Martínez
Publikováno v:
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientia
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientia
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
The Transforming Growth Factor-β (TGFβ) signaling pathway controls transcription by regulating enhancer activity. How TGFβ-regulated enhancers are selected and what chromatin changes are associated with TGFβ-dependent enhancers regulation are sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1324a35d03c0c09de915407068008947
https://hdl.handle.net/10668/3679
https://hdl.handle.net/10668/3679