Zobrazeno 1 - 10
of 289
pro vyhledávání: '"José A Luchsinger"'
Autor:
Howard H Feldman, José A Luchsinger, Gabriel C Léger, Curtis Taylor, Diane M Jacobs, David P Salmon, Steven D Edland, Karen Messer, Carolyn Revta, Sarah A Flowers, Kerry S Jones, Albert Koulman, Kevin E Yarasheski, Philip B Verghese, Venky Venkatesh, Henrik Zetterberg, January Durant, Jody-Lynn Lupo, Gary E Gibson, ADCS BenfoTeam Study Group
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0302998 (2024)
BackgroundBenfotiamine provides an important novel therapeutic direction in Alzheimer's disease (AD) with possible additive or synergistic effects to amyloid targeting therapeutic approaches.ObjectiveTo conduct a seamless phase 2A-2B proof of concept
Externí odkaz:
https://doaj.org/article/1adfda9ed09d49c99461ba5018b477fc
Autor:
Ana V Diez Roux, Jana A Hirsch, José A Luchsinger, Peter James, Kari A Moore, Yvonne L Michael, Brisa Sanchez, Timothy M Hughes, Marcia P Jimenez, Steven Melly, Kathleen Hayden, Lilah M Besser
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction The burden of Alzheimer’s disease (AD) and AD-related dementias (ADRD) is increasing nationally and globally, with disproportionate impacts on lower-income, lower education and systematically marginalised older adults. Presence of ineq
Externí odkaz:
https://doaj.org/article/7dcf740da5234cfcb3b7456f24573e46
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Graphical AbstractSummary of the study.
Externí odkaz:
https://doaj.org/article/0c398ee6544545fc9f6bf32dae0026c3
Autor:
Mildred Ramirez, Jeanne A. Teresi, Julie Ellis, Paloma Gonzalez-Lopez, Stephanie Silver, Mojdeh Rutigliano, Josephine Vidal-Manzano, Gabriel Boratgis, Davangere P. Devanand, Irena van Meer, Ismaa Bhatti, Usama Bhatti, José A. Luchsinger
Publikováno v:
Aging & Mental Health. :1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de95afbf2fc8fc40ae5664ba3a0fe220
https://doi.org/10.1080/13607863.2023.2207167
https://doi.org/10.1080/13607863.2023.2207167
Autor:
James Zou, David Park, Aubrey Johnson, Xinyang Feng, Michelle Pardo, Jeanelle France, Zeljko Tomljanovic, Adam M. Brickman, Devangere P. Devanand, José A. Luchsinger, William C. Kreisl, Frank A. Provenzano, for the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Positron emission tomography (PET) imaging targeting neurofibrillary tau tangles is increasingly used in the study of Alzheimer's disease (AD), but its utility may be limited by conventional quantitative or qualitative evaluatio
Externí odkaz:
https://doaj.org/article/36feef8dadd34469a7148e2b2f5d9570
Autor:
Whitney Wharton, Andrea Anderson, Kathleen M. Hayden, Owen T Carmichael, Jeanne M Clark, José A. Luchsinger, Mark Espeland, Sevil Yasar
Publikováno v:
Diabetes, Obesity and Metabolism. 24:2443-2453
To determine whether antihypertensive medication (AHM) acting through the renin angiotensin system (RAS-AHM), compared with other AHM, can mitigate effects on cognitive function and risk for impairment in a population with type 2 diabetes mellitus (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc98d5802ad9ec4dc5913a3dd90669d
https://doi.org/10.1111/dom.14838
https://doi.org/10.1111/dom.14838
Autor:
Leah V. Estrada, Jordan M. Harrison, Andrew W. Dick, José A. Luchsinger, Lara Dhingra, Patricia W. Stone
Publikováno v:
Journal of palliative medicine. 25(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab2a354ce6164e2ad2bfe69781be69e
https://pubmed.ncbi.nlm.nih.gov/35143358
https://pubmed.ncbi.nlm.nih.gov/35143358
Autor:
Timothy M. Hughes, Jordan Tanley, Haiying Chen, Christopher L. Schaich, Joseph Yeboah, Mark A. Espeland, Joao A. C. Lima, Bharath Ambale-Venkatesh, Erin D. Michos, Jingzhong Ding, Kathleen Hayden, Ramon Casanova, Suzanne Craft, Stephen R. Rapp, José A. Luchsinger, Annette L. Fitzpatrick, Susan R. Heckbert, Wendy S. Post, Gregory L. Burke
Publikováno v:
medRxiv
BackgroundSubclinical cardiovascular disease (CVD) measures may reflect biological pathways that contribute to increased risk for coronary heart disease (CHD) events, stroke, and dementia beyond conventional risk scores.MethodsThe Multi-Ethnic Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b68fdfa1196100e7482051eee6fe0d
https://europepmc.org/articles/PMC10187443/
https://europepmc.org/articles/PMC10187443/
Autor:
Seyed Hani Hojjati, Gloria C. Chiang, Tracy A. Butler, Mony De Leon, Ajay Gupta, Yi Li, Mert R. Sabuncu, Farnia Feiz, Siddharth Nayak, Jacob Shteingart, Sindy Ozoria, Saman Gholipour Picha, Antonio Fernández, Yaakov Stern, José A. Luchsinger, Davangere P. Devanand, Qolamreza R. Razlighi
Studies on the histopathology of Alzheimer’s disease (AD) strongly suggest that extracellular β-amyloid (Aβ) plaques promote the spread of neurofibrillary tau tangles. Despite well-documented spatial discrepancies between these two proteinopathie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1336824410d9538750367797c9f593b6
https://doi.org/10.1101/2023.03.31.23288013
https://doi.org/10.1101/2023.03.31.23288013
Autor:
Brady, Rippon, Priya, Palta, Mouna, Tahmi, Greysi, Sherwood, Luisa, Soto, Sandino, Cespedes, Yanette, Mesen, Hengda, He, Krystal, Laing, Herman, Moreno, Jeanne, Teresi, Qolamreza, Razlighi, Adam M, Brickman, Henrik, Zetterberg, José A, Luchsinger
Publikováno v:
Journal of Alzheimer's Disease. 87:1229-1238
Background: Determining amyloid positivity is possible with cerebrospinal fluid and brain imaging of amyloid, but these methods are invasive and expensive. Objective: To relate plasma amyloid-β (Aβ), measured using Single-molecule array (Simoatrade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3022b82f0da62a3a16350a586f086a
https://doi.org/10.3233/jad-210391
https://doi.org/10.3233/jad-210391