Expanding the Chemical Space of Non‐Proteinogenic N 4 ‐Substituted Asparagine: Racemic, Enantioenriched, and Deuterated Derivatives

Autor: Emanuele F. Pissinati, José A. C. Delgado, Pedro A. M. Moro, José T. M. Correia, Roberto G. S. Berlinck, Márcio W. Paixão

Publikováno v: European Journal of Organic Chemistry.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::376d9f4e8a0de7bc5f7833d993b90a6a
https://doi.org/10.1002/ejoc.202300274

Post-synthetic functionalization of tryptophan protected peptide sequences through indole (C-2) photocatalytic alkylation

Autor: Lutz Ackermann, Márcio W. Paixão, José A C Delgado, Nikolaos Kaplaneris, Darlon I. Bernardi, Rafaely N. Lima, Roberto G. S. Berlinck

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

We report a selective, mild, and efficient C-H functionalization of tryptophan and tryptophan-containing peptides with activated α-bromo-carbonyl compounds under visible-light irradiation. The protocol efficiency is outlined by the wide substrate sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2627b0b060b5553afba285cb033b7172
https://doi.org/10.1039/d1cc01822a

Photoinduced deaminative strategies: Katritzky salts as alkyl radical precursors

Autor: Wanderson C de Souza, José A C Delgado, Márcio W. Paixão, José Tiago M Correia, Bianca T. Matsuo, Vitor A. Fernandes

Publikováno v: Chemical Communications. 56:503-514

Primary amines are one of the most predominant functional groups found in organic molecules. These entities help form the chemical architecture of natural products, bioactive molecules, synthetic building blocks and catalysts. Due to their ubiquitous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e374e516a63eb863d5af4268aa237b0a
https://doi.org/10.1039/c9cc08348k

Electrochemical Installation of CFH

Autor: Camila M, Kisukuri, Vitor A, Fernandes, José A C, Delgado, Andreas P, Häring, Márcio W, Paixão, Siegfried R, Waldvogel

Publikováno v: Chemical record (New York, N.Y.). 21(9)

Electrosynthesis can be considered a powerful and sustainable methodology for the synthesis of small organic molecules. Due to its intrinsic ability to generate highly reactive species under mild conditions by anodic oxidation or cathodic reduction,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ed5a1eb488015772be48acd6f83f4cc
https://pubmed.ncbi.nlm.nih.gov/34151507

One-pot organocatalytic/multicomponent approach for the preparation of novel enantioenriched non-natural selenium-based peptoids and peptide-peptoid conjugates

Autor: Márcio W. Paixão, Antonio L. Braga, Alexander F. de la Torre, Fábio Z. Galetto, Akbar Ali, José A C Delgado

Publikováno v: Molecular diversity. 24(1)

A combined organocatalytic and multicomponent synthetic approach was designed for the preparation of selenium-based peptoids and peptide-peptoid conjugates. This single-step synthetic protocol comprises the organocatalytic asymmetric insertion of phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9748e7379efd48d89e7393541af2e409
https://pubmed.ncbi.nlm.nih.gov/30778816