Zobrazeno 1 - 10
of 228
pro vyhledávání: '"José Rueff"'
Publikováno v:
Research in Statistics, Vol 2, Iss 1 (2024)
Chromosomal fragile sites (CFSs) are loci or regions susceptible to spontaneous or induced occurrence of breaks and rearrangements. They are classified in two main categories, rare and common, depending on their frequency in the population. In order
Externí odkaz:
https://doaj.org/article/2fc6c9184e1b48a5843ebac669ebb961
Publikováno v:
Journal of Xenobiotics, Vol 14, Iss 2, Pp 575-603 (2024)
Progesterone receptor membrane component 1 (PGRMC1) is one of few proteins that have been recently described as direct modulators of the activity of human cytochrome P450 enzymes (CYP)s. These enzymes form a superfamily of membrane-bound hemoproteins
Externí odkaz:
https://doaj.org/article/c881402b56ee4ab29ec0f1303888a296
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Genetic compositions of distinct human populations are different. How genomic variants influence many common and rare genetic diseases is always of great medical and anthropological interest, and understanding of genetic architectures of pop
Externí odkaz:
https://doaj.org/article/831c3538554b467dbb6e482375cbbf8b
Autor:
Francisco Esteves, Cristina M. M. Almeida, Sofia Silva, Inês Saldanha, Philippe Urban, José Rueff, Denis Pompon, Gilles Truan, Michel Kranendonk
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1083 (2023)
A unique cytochrome P450 (CYP) oxidoreductase (CPR) sustains activities of human microsomal CYPs. Its function requires toggling between a closed conformation enabling electron transfers from NADPH to FAD and then FMN cofactors and open conformations
Externí odkaz:
https://doaj.org/article/f62d15d3be7b4883af44a3ed7f77817f
Publikováno v:
Journal of Xenobiotics, Vol 11, Iss 3, Pp 94-114 (2021)
Human Cytochrome P450 (CYP) enzymes constitute a superfamily of membrane-bound hemoproteins that are responsible for the metabolism of a wide variety of clinically, physiologically, and toxicologically important compounds. These heme-thiolate monooxy
Externí odkaz:
https://doaj.org/article/f62a7b0591ab4024b2099490050f7ec1
Autor:
Marília Ladeira de Araújo, Bruno Costa Gomes, Paula Pícoli Devóz, Nathália de Assis Aguilar Duarte, Diego Luis Ribeiro, Adriana Ladeira de Araújo, Bruno Lemos Batista, Lusânia Maria Greggi Antunes, Fernando Barbosa, António Sebastião Rodrigues, José Rueff, Gustavo Rafael Mazzaron Barcelos
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Experimental and epidemiologic studies have shown that lead (Pb) is able to induce epigenetic modifications, such as changes in DNA methylation profiles, in chromatin remodeling, as well as the expression of non-coding RNAs (ncRNAs). However, very li
Externí odkaz:
https://doaj.org/article/12e43e3e7c994f408ae47469f22107dd
Autor:
Francisco Esteves, Diana Campelo, Bruno Costa Gomes, Philippe Urban, Sophie Bozonnet, Thomas Lautier, José Rueff, Gilles Truan, Michel Kranendonk
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/4feb1c7e46344f58a5e4ad60ebee8dd1
Autor:
Francisco Esteves, Diana Campelo, Bruno Costa Gomes, Philippe Urban, Sophie Bozonnet, Thomas Lautier, José Rueff, Gilles Truan, Michel Kranendonk
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
NADPH cytochrome P450 oxidoreductase (CPR) is the obligatory electron supplier that sustains the activity of microsomal cytochrome P450 (CYP) enzymes. The variant nature of the isoform-specific proximal interface of microsomal CYPs indicates that CPR
Externí odkaz:
https://doaj.org/article/78cc9bf1507040fe9210808633b8f4ef
Autor:
Kranendonk, Francisco Esteves, Cristina M. M. Almeida, Sofia Silva, Inês Saldanha, Philippe Urban, José Rueff, Denis Pompon, Gilles Truan, Michel
Publikováno v:
Biomolecules; Volume 13; Issue 7; Pages: 1083
A unique cytochrome P450 (CYP) oxidoreductase (CPR) sustains activities of human microsomal CYPs. Its function requires toggling between a closed conformation enabling electron transfers from NADPH to FAD and then FMN cofactors and open conformations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::58073c7233979bf6fe68cbee90536bdf
Autor:
Rita Lourenço, Miguel Lança, Octávia Monteiro Gil, Joana Cardoso, Teresa Lourenço, José Pereira‑Leal, António Rodrigues, José Rueff, Susana Nunes Silva
Publikováno v:
Molecular Medicine Reports. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::796a243fc005c107733419b4696feca3
https://doi.org/10.3892/mmr.2023.13023
https://doi.org/10.3892/mmr.2023.13023