Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jorma Haarala"'
Autor:
Bert van Veen, Jorma Haarala, Inna Miroshnyk, Anna Shevchenko, Lars-Olof Pietilä, Sabiruddin Mirza, Jouko Yliruusi, Erkki Kolehmainen, Nonappa, Jukka Salmia, Kai Sinervo
Publikováno v:
Crystal Growth and Design. 13(11):4877-4884
The cocrystal formation potential of itraconazole, a potent antifungal drug, with C2–C10 aliphatic dicarboxylic acids has been investigated. Using two experimental screening techniques (solvent-assisted grinding and evaporation-based crystallizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20fdd15c602d09bc397b9c8935559bd
https://doi.org/10.1021/cg401061t
https://doi.org/10.1021/cg401061t
Publikováno v:
Crystal Growth & Design. 13:346-351
Exact knowledge of the crystal structure of drugs and lead compounds plays a significant role in the fields of crystal engineering, docking, computational modeling (drug–receptor interactions), and rational design of potent drugs in pharmaceutical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acd8a5d4ab616f5218ba936740ed702
https://doi.org/10.1021/cg3015282
https://doi.org/10.1021/cg3015282
Autor:
Hélder A. Santos, Bert van Veen, Kristýna Jelínková, Kaisa Syrjänen, Luis M. Bimbo, Jouko Yliruusi, Inna Miroshnyk, Anna Shevchenko, Jorma Haarala, Juha Kiesvaara
Publikováno v:
International Journal of Pharmaceutics. 436:403-409
Cocrystallization and salt formation have been shown to entail substantial promise in tailoring the physicochemical properties of drug compounds, in particular, their dissolution and hygroscopicity. In this work, we report on the preparation and comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8831f5c0433024c1c727903263c5d39c
https://doi.org/10.1016/j.ijpharm.2012.06.045
https://doi.org/10.1016/j.ijpharm.2012.06.045
Autor:
Arto Tolvanen, Jouko Yliruusi, Saara Tiittanen, Karjalainen Arto Johannes, Mäkelä Mikko, David Din Belle, Veli Pekka Tanninen, Anna Shevchenko, Jorma Haarala, Inna Miroshnyk
Publikováno v:
Organic Process Research & Development. 15:666-672
The need for effective solid-form screening approaches, especially designed for the early discovery phases, is well recognized within the pharmaceutical industry. Here we report on the early polymorphism and solvatomorphism evaluation of a new drug c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e7ec0bf8e5c63090aedac750bf1c973
https://doi.org/10.1021/op200026f
https://doi.org/10.1021/op200026f
Publikováno v:
Analytica Chimica Acta. 542:178-185
A constrained total-line-shape (CTLS) fitting strategy for organic impurity analysis from 1H NMR spectra was developed and assessed by studying two examples. In general, total-line-shape fitting allows integration of overlapping lines without sufferi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7386e1af643064ec536ec7b284edf245
https://doi.org/10.1016/j.aca.2005.03.060
https://doi.org/10.1016/j.aca.2005.03.060
Publikováno v:
Archiv der Pharmazie. 321:103-106
Decompositions of dithranol and butantrone (10-butyryldithranol) were studied in buffer solutions. Half lives at pH 9.4, 7.4 and 6.5 were 0.6, 1.2 and 3.0 h for dithranol, and 1.3, 15 and 30 h for butantrone, respectively. 1,8-Dihydroxyanthraquinone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fc2b07d03bdea72773c7f7dc51f09e
https://doi.org/10.1002/ardp.19883210214
https://doi.org/10.1002/ardp.19883210214
Publikováno v:
ChemInform. 19
Decompositions of dithranol and butantrone (10-butyryldithranol) were studied in buffer solutions. Half lives at pH 9.4, 7.4 and 6.5 were 0.6, 1.2 and 3.0 h for dithranol, and 1.3, 15 and 30 h for butantrone, respectively. 1,8-Dihydroxyanthraquinone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dfc9ab666089e4109937bbbecf1cd47
https://doi.org/10.1002/chin.198824172
https://doi.org/10.1002/chin.198824172
Autor:
Harry G. Brittain
Profiles of Drug Substances, Excipients, and Related Methodology, Volume 44, presents comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug
