Výsledky vyhledávání - "Joris van der Veeken"

Akademický článek

Genetic and epigenetic variation in the lineage specification of regulatory T cells

Autor: Aaron Arvey, Joris van der Veeken, George Plitas, Stephen S Rich, Patrick Concannon, Alexander Y Rudensky

Publikováno v: eLife, Vol 4 (2015)

Regulatory T (Treg) cells, which suppress autoimmunity and other inflammatory states, are characterized by a distinct set of genetic elements controlling their gene expression. However, the extent of genetic and associated epigenetic variation in the

Externí odkaz: https://doaj.org/article/9f7a3b8dce3c43e5ad7262d193f409af

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Regulatory T cells function in established systemic inflammation and reverse fatal autoimmunity

Autor: Yongqiang Feng, Zhong-Min Wang, Michail Schizas, Regina Bou-Puerto, Beatrice Hoyos, Joris van der Veeken, Wei Hu, Jacob Verter, Alexander Y. Rudensky

Publikováno v: Nature Immunology. 22:1163-1174

The immunosuppressive function of regulatory T (Treg) cells is dependent on continuous expression of the transcription factor Foxp3. Foxp3 loss of function or induced ablation of Treg cells results in a fatal autoimmune disease featuring all known ty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04947f8b70feddc5d3dd961e04924ab5
https://doi.org/10.1038/s41590-021-01001-4

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Feeding fiction

Autor: Joris van der Veeken, Pieternel A. Luning, Wim Huisman, Saskia M. van Ruth, Pieter Dekker

Publikováno v: van Ruth, S M, van der Veeken, J, Dekker, P, Luning, P A & Huisman, W 2020, ' Feeding fiction : Fraud vulnerability in the food service industry ', Food Research International, vol. 133, 109158, pp. 1-8 . https://doi.org/10.1016/j.foodres.2020.109158
Food Research International 133 (2020)
Food Research International, 133
Food Research International, 133:109158, 1-8. Elsevier Ltd

This study examines fraud vulnerability in the food service industry; identifies underlying fraud vulnerability factors; and studies the differences in fraud vulnerability between casual dining restaurants, fine dining restaurants and mass caterers f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4d79bad054c80b7a1f30d250b6a2ad
http://www.scopus.com/inward/record.url?scp=85081153496&partnerID=8YFLogxK

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FoxP3 can fold into two distinct dimerization states with divergent functional implications for T cell homeostasis

Autor: Fangwei Leng, Wenxiang Zhang, Ricardo N. Ramirez, Juliette Leon, Yi Zhong, Joris van der Veeken, Alexander Y. Rudensky, Christophe Benoist, Sun Hur

FoxP3 is an essential transcription factor (TF) for immunologic homeostasis, but how it utilizes the common forkhead DNA-binding domain (DBD) to perform its unique function remains poorly understood. We here demonstrate that, unlike other known forkh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63bf46a7c29531911a0a86c37a997efc
https://doi.org/10.1101/2022.02.08.479534

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The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis

Autor: Fangwei Leng, Wenxiang Zhang, Ricardo N. Ramirez, Juliette Leon, Yi Zhong, Lifei Hou, Koichi Yuki, Joris van der Veeken, Alexander Y. Rudensky, Christophe Benoist, Sun Hur

Publikováno v: Immunity. 55:1354-1369.e8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaeccac82b43a1526f425a25e96b9dfd
https://doi.org/10.1016/j.immuni.2022.07.002

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Regulatory T Cell Function in Established Systemic Autoimmune Inflammation: Reversal and Containment of a Fatal Disease

Autor: Zhong-Min Wang, Regina Bou Puerto, Jacob Verter, Beatrice Hoyos, Joris van der Veeken, Wei Hu, Yongqiang Feng, Alexander Y. Rudensky, Michail Schizas

The immunosuppressive function of regulatory T (Treg) cells is dependent on continuous expression of the transcription factor Foxp3. Foxp3 loss-of-function or induced ablation of Treg cells results in a fatal autoimmune disease featuring all known ty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c89a3d1d6abaee37858bb76c26c0b55
https://doi.org/10.21203/rs.3.rs-153417/v1

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FXR mediates T cell-intrinsic responses to reduced feeding during infection

Autor: Joris van der Veeken, Clarissa Campbell, Anthony J. Michaels, Naofumi Takemoto, Alexander Y. Rudensky, Andrew M. Intlekofer, Paul Cohen, François Marchildon, Yuri Pritykin, Michail Schizas, Christina S. Leslie

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance Anorexia or decreased appetite is a common feature of infection. The effects of acute nutritional stress on effector T cells, which are required for pathogen-specific responses and protective immunological memory, are not fully understoo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96949678120bb0cf31e495ff992ddfed
https://pubmed.ncbi.nlm.nih.gov/33318189

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A unified atlas of CD8 T cell dysfunctional states in cancer and infection

Autor: Yuri Pritykin, Allison R. Pine, Alexander Y. Rudensky, Yi Zhong, Joris van der Veeken, Linas Mazutis, Merve Sahin, Dana Pe'er, Christina S. Leslie

Publikováno v: Molecular cell. 81(11)

Summary CD8 T cells play an essential role in defense against viral and bacterial infections and in tumor immunity. Deciphering T cell loss of functionality is complicated by the conspicuous heterogeneity of CD8 T cell states described across experim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0201a25e4b7c8ff4057685456dd6786b
https://pubmed.ncbi.nlm.nih.gov/34087178

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