Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Joris J T H, Roelofs"'
Autor:
Christine C. A. van Linge, Robert F.J. Kullberg, Osoul Chouchane, Joris J. T. H. Roelofs, Wil H. F. Goessens, Cornelis van ‘t Veer, Jean-Claude Sirard, Alex F. de Vos, Tom van der Poll
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveAntimicrobial resistance is an emerging problem and multi-drug resistant (MDR) Klebsiella pneumoniae (K. pneumoniae) represents an enormous risk of failing therapy in hospital-acquired pneumonia. The current study aimed to determine the immu
Externí odkaz:
https://doaj.org/article/4c29503838964b84965265ad5b1f23b3
Autor:
Charissa E. van den Brom, Caitlin Bozic, Chantal A. Polet, Annabel Bongers, Anita M. Tuip-de Boer, Roselique Ibelings, Joris J. T. H. Roelofs, Nicole P. Juffermans
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-11 (2024)
Abstract Background Acute respiratory distress syndrome (ARDS) is characterized by alveolar edema that can progress to septal fibrosis. Mechanical ventilation can augment lung injury, termed ventilator-induced lung injury (VILI). Connective tissue gr
Externí odkaz:
https://doaj.org/article/0a0ace6f7a96473483c3ddad8f4341c6
Autor:
Igor Oliveira da Silva, Nicole K. de Menezes, Heloisa D. Jacobina, Antonio Carlos Parra, Felipe Lima Souza, Leticia Cardoso Castro, Joris J. T. H. Roelofs, Alessandra Tammaro, Samirah Abreu Gomes, Talita Rojas Sanches, Lucia Andrade
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract In critically ill patients, overweight and obesity are associated with acute respiratory distress syndrome and acute kidney injury (AKI). However, the effect of obesity on ischemia–reperfusion injury (IRI)-induced AKI is unknown. We hypoth
Externí odkaz:
https://doaj.org/article/00d0fe8cf75642a4aa224907aa964546
Autor:
Daan P. van den Brink, Derek J. B. Kleinveld, Annabel Bongers, Jaël Vos, Joris J. T. H. Roelofs, Nina C. Weber, Jaap D. van Buul, Nicole P. Juffermans
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-9 (2023)
Abstract Background Endothelial injury and permeability are a hallmark of sepsis. Initial resuscitation of septic patients with crystalloids is associated with aggravation of endothelial permeability, which may be related either to low protein conten
Externí odkaz:
https://doaj.org/article/2e71c8bb73db4b7498d7cd7a174e6bfb
Autor:
Igor Oliveira da Silva, Nicole K. de Menezes, Heloisa D. Jacobina, Antonio Carlos Parra, Felipe Lima Souza, Leticia Cardoso Castro, Joris J. T. H. Roelofs, Alessandra Tammaro, Samirah Abreu Gomes, Talita Rojas Sanches, Lucia Andrade
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/820f2cb7f14b4b4d877a5325db1d41ae
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Liver kinase B1 (Lkb1, gene name Stk11) functions as a tumor suppressor in cancer. Myeloid cell Lkb1 potentiates lung inflammation induced by the Gram-negative bacterial cell wall component lipopolysaccharide and in host defense d
Externí odkaz:
https://doaj.org/article/dd7daa0e6d3549e3aee653179b7be5a3
Autor:
Robert B. Klanderman, Joachim J. Bosboom, Denise P. Veelo, Joris J. T. H. Roelofs, Dirk de Korte, Robin van Bruggen, Liffert Vogt, Jaap D. van Buul, Markus W. Hollmann, Margreeth B. Vroom, Nicole P. Juffermans, Bart F. Geerts, Alexander P. J. Vlaar
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Transfusion-associated circulatory overload (TACO) is the leading cause of transfusion related morbidity and mortality. The only treatment is empirical use of furosemide. Our aim was to investigate if furosemide can prevent TACO. A randomize
Externí odkaz:
https://doaj.org/article/476d1c299fa947349cdd2af40e6cbc90
Autor:
Anoek L I van Leeuwen, Elise Beijer, Roselique Ibelings, Nicole A M Dekker, Marjolein R A van der Steen, Joris J T H Roelofs, Matijs van Meurs, Grietje Molema, Charissa E van den Brom
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0293673 (2023)
BackgroundThe endothelial angiopoietin/Tie2 system is an important regulator of endothelial permeability and targeting Tie2 reduces hemorrhagic shock-induced organ edema in males. However, sexual dimorphism of the endothelium has not been taken into
Externí odkaz:
https://doaj.org/article/2ac4c83dd5644c58a18fa8b1e6658a17
Autor:
Abdulrahman Alshalani, Marit B de Wissel, Anita M Tuip-de Boer, Joris J T H Roelofs, Robin van Bruggen, Jason P Acker, Nicole P Juffermans
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0288308 (2023)
Transfusion of red blood cells (RBCs) has been associated with adverse outcomes. Mechanisms may be related to donor sex and biological age of RBC. This study hypothesized that receipt of female blood is associated with decreased post-transfusion reco
Externí odkaz:
https://doaj.org/article/75511daef9ad4b679f2586b0c2ec82cc
Autor:
Eline C. B. Eskes, Martijn J. C. van derLienden, Joris J. T. H. Roelofs, Liffert Vogt, Johannes M. F. G. Aerts, Jan Aten, Carla E. M. Hollak
Publikováno v:
JIMD Reports, Vol 62, Iss 1, Pp 15-21 (2021)
Abstract Acid sphingomyelinase deficiency (ASMD) is a lysosomal storage disease (LSD) in which sphingomyelin accumulates due to deficient acid sphingomyelinase. In the chronic visceral subtype, organ manifestations are generally limited to the spleen
Externí odkaz:
https://doaj.org/article/0d8fd9418c5847569222bd253ca6e84e