Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Joris J, Benschop"'
Autor:
Eoghan O'Duibhir, Philip Lijnzaad, Joris J Benschop, Tineke L Lenstra, Dik van Leenen, Marian JA Groot Koerkamp, Thanasis Margaritis, Mariel O Brok, Patrick Kemmeren, Frank CP Holstege
Publikováno v:
Molecular Systems Biology, Vol 10, Iss 6, Pp 1-14 (2014)
Abstract Growth condition perturbation or gene function disruption are commonly used strategies to study cellular systems. Although it is widely appreciated that such experiments may involve indirect effects, these frequently remain uncharacterized.
Externí odkaz:
https://doaj.org/article/632580814a554de6a7ae1d2d159fbd1a
Autor:
Michael Hecker, Annette Dreisbach, Jaap Willem Back, Herman Groen, José C. Duipmans, Ewoud Reilman, Dörte Becher, Andreas Otto, Dennis G. A. M. Koedijk, Min Wang, Girbe Buist, Jan Maarten van Dijl, Ruben A. T. Mars, Hendrik P. J. Bonarius, Joris J. Benschop, Magdalena M. van der Kooi-Pol, Jörg Bernhardt, Marcel F. Jonkman, Katrin Bäsell
Publikováno v:
Journal of Proteome Research, 19(8), 2997-3010. NLM (Medline)
The opportunistic pathogen Staphylococcus aureus has become a major threat for human health and well-being by developing resistance to antibiotics and by fast evolution into new lineages that rapidly spread within the healthy human population. This c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfecea0b8d19b1df6196e42feab6a3d
https://research.rug.nl/en/publications/147b1cc2-d87f-45e6-a9f6-0090fff4a9aa
https://research.rug.nl/en/publications/147b1cc2-d87f-45e6-a9f6-0090fff4a9aa
Autor:
Jiashun Zheng, Joris J Benschop, Michael Shales, Patrick Kemmeren, Jack Greenblatt, Gerard Cagney, Frank Holstege, Hao Li, Nevan J Krogan
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-12 (2010)
Abstract The regulation of gene expression is, in large part, mediated by interplay between the general transcription factors (GTFs) that function to bring about the expression of many genes and site‐specific DNA‐binding transcription factors (ST
Externí odkaz:
https://doaj.org/article/b8e47565a7844e6393c7a94ef43ea817
Autor:
Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor
Publikováno v:
Genetics. 222(3)
The NuA4 lysine acetyltransferase complex acetylates histone and nonhistone proteins and functions in transcription regulation, cell cycle progression, and DNA repair. NuA4 harbors an interesting duality in that its catalytic module can function inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62dd2101df386a2254e91041f7a05c97
https://pubmed.ncbi.nlm.nih.gov/36066422
https://pubmed.ncbi.nlm.nih.gov/36066422
Autor:
Michael S. Kobor, Maria J. Aristizabal, Kristy Dever, Frank C. P. Holstege, Gian Luca Negri, Nevan J. Krogan, Joris J. Benschop, Ivan Sadowski, Mary Shen, Nicole Hawe
Publikováno v:
J Biol Chem
Fcp1 is a protein phosphatase that facilitates transcription elongation and termination by dephosphorylating the C-terminal domain of RNA polymerase II. High-throughput genetic screening and gene expression profiling of fcp1 mutants revealed a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9090ee99304c50667bb8fcc74912c80
https://doi.org/10.1074/jbc.ra119.008515
https://doi.org/10.1074/jbc.ra119.008515
Autor:
Maria J Aristizabal, Gian Luca Negri, Joris J Benschop, Frank C P Holstege, Nevan J Krogan, Michael S Kobor
Publikováno v:
PLoS Genetics, Vol 9, Iss 8, p e1003758 (2013)
The C-terminal domain (CTD) of RNA polymerase II (RNAPII) is composed of heptapeptide repeats, which play a key regulatory role in gene expression. Using genetic interaction, chromatin immunoprecipitation followed by microarrays (ChIP-on-chip) and mR
Externí odkaz:
https://doaj.org/article/be28d2c4e3da4c139d0bcc6a316a6bce
Autor:
Annette, Dreisbach, Min, Wang, Magdalena M, van der Kooi-Pol, Ewoud, Reilman, Dennis G A M, Koedijk, Ruben A T, Mars, José, Duipmans, Marcel, Jonkman, Joris J, Benschop, Hendrik P J, Bonarius, Herman, Groen, Michael, Hecker, Andreas, Otto, Katrin, Bäsell, Jörg, Bernhardt, Jaap Willem, Back, Dörte, Becher, Girbe, Buist, Jan Maarten, van Dijl
Publikováno v:
Journal of proteome research. 19(8)
The opportunistic pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96225699d4ffb171fa38e3c0683ff373
https://pubmed.ncbi.nlm.nih.gov/32529827
https://pubmed.ncbi.nlm.nih.gov/32529827
Autor:
Thanasis Margaritis, Vincent Oreal, Nathalie Brabers, Laetitia Maestroni, Adeline Vitaliano-Prunier, Joris J Benschop, Sander van Hooff, Dik van Leenen, Catherine Dargemont, Vincent Géli, Frank C P Holstege
Publikováno v:
PLoS Genetics, Vol 8, Iss 9, p e1002952 (2012)
Histone H3 di- and trimethylation on lysine 4 are major chromatin marks that correlate with active transcription. The influence of these modifications on transcription itself is, however, poorly understood. We have investigated the roles of H3K4 meth
Externí odkaz:
https://doaj.org/article/ec03e2d44fdd4335b85948af67557d71
Autor:
Joris J. Benschop, Wouter Cornelis Puijk, Drohpatie Timmers‐Parohi, Peter Timmerman, Henk Hiemstra, Linde E. J. Smeenk, Jan H. van Maarseveen
Publikováno v:
ChemBioChem, 16(1), 91-99. Wiley-VCH Verlag
Making peptide-based molecules that mimic functional interaction sites on proteins remains a challenge in biomedical sciences. Here, we present a robust technology for the covalent assembly of highly constrained and discontinuous binding site mimics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7c383806dff437d3a5a96e4d4dc7f3
https://dare.uva.nl/personal/pure/en/publications/reconstructing-the-discontinuous-and-conformational-1-3loop-binding-site-on-hfshhcg-by-using-highly-constrained-multicyclic-peptides(a4044ab4-e2dd-4604-bd2f-b579078c11e5).html
https://dare.uva.nl/personal/pure/en/publications/reconstructing-the-discontinuous-and-conformational-1-3loop-binding-site-on-hfshhcg-by-using-highly-constrained-multicyclic-peptides(a4044ab4-e2dd-4604-bd2f-b579078c11e5).html
Autor:
Danielle Carroll, John Elvin, Simon T. Barry, Christine J. Rossant, Joris J. Benschop, Eldar E Kim, Frances Neal, Ling Huang, Edward H. Walker, Tristan J. Vaughan
Publikováno v:
mAbs. 6:1425-1438
Generation of functional antibodies against integral membrane proteins such as the G-protein coupled receptor CXCR2 is technically challenging for several reasons, including limited epitope accessibility, the requirement for a lipid environment to ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eadd41c44080ce3b82ae4fa01b304bd
https://doi.org/10.4161/mabs.34376
https://doi.org/10.4161/mabs.34376