Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Joris Beld"'
Autor:
Emily M. Esquea, Lorela Ciraku, Riley G. Young, Jessica Merzy, Alexandra N. Talarico, Nusaiba N. Ahmed, Mangalam Karuppiah, Anna Ramesh, Adam Chatoff, Claudia V. Crispim, Adel A. Rashad, Simon Cocklin, Nathaniel W. Snyder, Joris Beld, Nicole L. Simone, Mauricio J. Reginato, Alexej Dick
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Breast cancer brain metastasis (BCBM) typically results in an end-stage diagnosis and is hindered by a lack of brain-penetrant drugs. Tumors in the brain rely on the conversion of acetate to acetyl-CoA by the enzyme acetyl-CoA synthetase 2 (ACSS2), a
Externí odkaz:
https://doaj.org/article/4ae2b15c3c5446188251b5c916b863e7
Publikováno v:
ACS Bio & Med Chem Au, Vol 4, Iss 2, Pp 86-94 (2023)
Externí odkaz:
https://doaj.org/article/531c2862aa8f4e24bcec521754a929a8
Publikováno v:
Biochemistry and Biophysics Reports, Vol 35, Iss , Pp 101549- (2023)
The acyl-acyl carrier protein synthetase enzyme enables some bacteria to scavenge free fatty acids from the environment for direct use in lipids. This fatty acid recycling pathway can help pathogens circumvent fatty acid synthase (FAS) inhibition wit
Externí odkaz:
https://doaj.org/article/042e1c196f954039ac79c684e4fb9c41
Autor:
Ronald Lucarelli, Norma Gorrochotegui-Escalante, Jessica Taddeo, Bettina Buttaro, Joris Beld, Vincent Tam
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Secondary bacterial infection (superinfection) post influenza is a serious clinical complication often leading to pneumonia and death. Eicosanoids are bioactive lipid mediators that play critical roles in the induction and resolution of inflammation.
Externí odkaz:
https://doaj.org/article/8f74544fd71f4f50819924e857db7dbd
Publikováno v:
Biotechnology Reports, Vol 29, Iss , Pp e00596- (2021)
Streptomycetes are bacteria of biotechnological importance since they are avid producers of secondary metabolites, including antibiotics. Progress in genome mining has recently shown that Streptomyces species encode for many biosynthetic gene cluster
Externí odkaz:
https://doaj.org/article/1a830af181f243038f51bb500b8ed777
Autor:
Young-Saeng Kim, Seong-Im Park, Jin-Ju Kim, Joseph S. Boyd, Joris Beld, Arnaud Taton, Kyoung-In Lee, Il-Sup Kim, James W. Golden, Ho-Sung Yoon
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
An excess of reactive oxygen species (ROS) can cause severe oxidative damage to cellular components in photosynthetic cells. Antioxidant systems, such as the glutathione (GSH) pools, regulate redox status in cells to guard against such damage. Dehydr
Externí odkaz:
https://doaj.org/article/658fed7c37ee4c5d933490400213a2c3
Autor:
Carla C. Uranga, Joris Beld, Anthony Mrse, Iván Córdova-Guerrero, Michael D. Burkart, Rufina Hernández-Martínez
Publikováno v:
Data in Brief, Vol 8, Iss , Pp 31-39 (2016)
The data described herein is related to the article with the title “Fatty acid esters produced by Lasiodiplodia theobromae function as growth regulators in tobacco seedlings” C.C. Uranga, J. Beld, A. Mrse, I. Cordova-Guerrero, M.D. Burkart, R. He
Externí odkaz:
https://doaj.org/article/6e4855ebe42f4f559aa26bdd3dcb2b8a
Manipulating fatty acid biosynthesis in microalgae for biofuel through protein-protein interactions.
Autor:
Jillian L Blatti, Joris Beld, Craig A Behnke, Michael Mendez, Stephen P Mayfield, Michael D Burkart
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e42949 (2012)
Microalgae are a promising feedstock for renewable fuels, and algal metabolic engineering can lead to crop improvement, thus accelerating the development of commercially viable biodiesel production from algae biomass. We demonstrate that protein-prot
Externí odkaz:
https://doaj.org/article/ed25096f3b4a4d7eacdeaf814c0baeb3
Publikováno v:
Journal of Bacteriology.
The rise of antibiotic-resistant pathogens poses a challenge to public health. The gut microbiome presents a promising source of new antimicrobials and treatments.
Autor:
Sanjay Das, Artem V. Trubnikov, Anton M. Novoselov, Alexander V. Kurkin, Joris Beld, Andrea Altieri, Sandhya Kortagere
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1628-1633
Excitotoxicity in the brain is a causal factor in several neurological and neurodegenerative disorders. Excitatory amino acid transporter 2 (EAAT2), an astrocytic glutamate transporter involved in the clearance of80% of synaptic glutamate, is conside