Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jori Tomassen"'
Autor:
Jori Tomassen, Anouk den Braber, Sven J. van der Lee, Lianne M. Reus, Elles Konijnenberg, Stephen F. Carter, Maqsood Yaqub, Bart N.M. van Berckel, Lyduine E. Collij, Dorret I. Boomsma, Eco J.C. de Geus, Philip Scheltens, Karl Herholz, Betty M. Tijms, Pieter Jelle Visser
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background: What combination of risk factors for Alzheimer’s disease (AD) are most predictive of cognitive decline in cognitively unimpaired individuals remains largely unclear. We studied associations between APOE genotype, AD-Polygenic R
Externí odkaz:
https://doaj.org/article/de2470f34ab8427f961bab5f7eb68c5e
Autor:
Rosha Babapour Mofrad, Philip Scheltens, SangYun Kim, Sungmin Kang, Young Chul Youn, Seong Soo A. An, Jori Tomassen, Bart N. M. van Berckel, Pieter Jelle Visser, Wiesje M. van der Flier, Charlotte E. Teunissen
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-10 (2021)
Abstract Objective We assessed the performance of plasma amyloid oligomerization tendency (OAβ) as a marker for abnormal amyloid status. Additionally, we examined long-term storage effects on plasma OAβ. Methods We included 399 subjects regardless
Externí odkaz:
https://doaj.org/article/b4d4b0f74e0c405c9f4317733a93b7c0
Autor:
Jori Tomassen, Anouk den Braber, Sophie M. van der Landen, Elles Konijnenberg, Charlotte E. Teunissen, Lisa Vermunt, Eco J. C. de Geus, Dorret I. Boomsma, Philip Scheltens, Betty M. Tijms, Pieter Jelle Visser
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction The contribution of genetic and environmental factors to the relation between cerebrospinal fluid (CSF) biomarkers and cognitive decline in preclinical Alzheimer's disease remains unclear. We studied this in initially cognitivel
Externí odkaz:
https://doaj.org/article/277af6272e3a491a827c46fdb6ccb8f0
Autor:
Jacoba A. van de Kreeke, Nienke Legdeur, Maryam Badissi, H. Ton Nguyen, Elles Konijnenberg, Jori Tomassen, Mara ten Kate, Anouk den Braber, Andrea B. Maier, H. Stevie Tan, Frank D. Verbraak, Pieter Jelle Visser
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Ocular imaging receives much attention as a source of potential biomarkers for dementia. In the present study, we analyze these ocular biomarkers in cognitively impaired and healthy participants in a population aged over 90 years
Externí odkaz:
https://doaj.org/article/bd4c311aa7d14ea68c1d56f730da6465
Autor:
Lyduine E. Collij, Silvia Ingala, Herwin Top, Viktor Wottschel, Kristine E. Stickney, Jori Tomassen, Elles Konijnenberg, Mara ten Kate, Carole Sudre, Isadora Lopes Alves, Maqsood M. Yaqub, Alle Meije Wink, Dennis Van ‘t Ent, Philip Scheltens, Bart N.M. vanBerckel, Pieter Jelle Visser, Frederik Barkhof, Anouk Den Braber
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Amyloid beta (Aβ) accumulation is the first pathological hallmark of Alzheimer's disease (AD), and it is associated with altered white matter (WM) microstructure. We aimed to investigate this relationship at a regional level in
Externí odkaz:
https://doaj.org/article/c4b13b8a0c6a4a42b7af36d1b23cafda
Autor:
Elles Konijnenberg, Stephen F. Carter, Mara ten Kate, Anouk den Braber, Jori Tomassen, Chinenye Amadi, Linda Wesselman, Hoang-Ton Nguyen, Jacoba A. van de Kreeke, Maqsood Yaqub, Matteo Demuru, Sandra D. Mulder, Arjan Hillebrand, Femke H. Bouwman, Charlotte E. Teunissen, Erik H. Serné, Annette C. Moll, Frank D. Verbraak, Rainer Hinz, Neil Pendleton, Adriaan A. Lammertsma, Bart N. M. van Berckel, Frederik Barkhof, Dorret I. Boomsma, Philip Scheltens, Karl Herholz, Pieter Jelle Visser
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Amyloid pathology is the pathological hallmark in Alzheimer’s disease (AD) and can precede clinical dementia by decades. So far it remains unclear how amyloid pathology leads to cognitive impairment and dementia. To design AD pr
Externí odkaz:
https://doaj.org/article/1550fd3ad24a4070bf47c772e48b117e
Autor:
Isabelle Bos, Stephanie J. B. Vos, Willemijn J. Jansen, Rik Vandenberghe, Silvy Gabel, Ainara Estanga, Mirian Ecay-Torres, Jori Tomassen, Anouk den Braber, Alberto Lleó, Isabel Sala, Anders Wallin, Petronella Kettunen, José L. Molinuevo, Lorena Rami, Gaël Chetelat, Vincent de la Sayette, Magda Tsolaki, Yvonne Freund-Levi, Peter Johannsen, The Alzheimer's Disease Neuroimaging Initiative, Gerald P. Novak, Inez Ramakers, Frans R. Verhey, Pieter Jelle Visser
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
We investigated whether amyloid-β (Aβ) and tau affected cognition in cognitively normal (CN) individuals, and whether norms for neuropsychological tests based on biomarker-negative individuals would improve early detection of dementia. We included
Externí odkaz:
https://doaj.org/article/7d99b5ef6ae14298a061444872adece3
Autor:
Jochum J van 't Hooft, Wiesje Pelkmans, Jori Tomassen, Cas Smits, Nienke Legdeur, Anouk den Braber, Frederik Barkhof, Bart van Berckel, Maqsood Yaqub, Philip Scheltens, Yolande AL Pijnenburg, Pieter Jelle Visser, Betty M Tijms
Publikováno v:
van 't Hooft, J J, Pelkmans, W, Tomassen, J, Smits, C, Legdeur, N, den Braber, A, Barkhof, F, van Berckel, B, Yaqub, M, Scheltens, P, Pijnenburg, Y A, Visser, P J & Tijms, B M 2023, ' Distinct disease mechanisms may underlie cognitive decline related to hearing loss in different age groups ', Journal of neurology, neurosurgery, and psychiatry, vol. 94, no. 4, pp. 314-320 . https://doi.org/10.1136/jnnp-2022-329726
Journal of neurology, neurosurgery, and psychiatry, 94(4), 314-320. BMJ Publishing Group
Journal of Neurology Neurosurgery and Psychiatry, 94(4), 314-320. BMJ Publishing Group
Journal of neurology, neurosurgery, and psychiatry, 94(4), 314-320. BMJ Publishing Group
Journal of Neurology Neurosurgery and Psychiatry, 94(4), 314-320. BMJ Publishing Group
BackgroundHearing loss in older adults is associated with increased dementia risk. Underlying mechanisms that connect hearing loss with dementia remain largely unclear.MethodsWe studied the association of hearing loss and biomarkers for dementia risk
Autor:
Betty M Tijms, Ellen M Vromen, Olav Mjaavatten, Henne Holstege, Lianne M Reus, Sven van der Lee, Kirsten EJ Wesenhagen, Luigi Lorenzini, Lisa Vermunt, Vikram Venkatraghavan, Niccoló Tesi, Jori Tomassen, Anouk den Braber, Julie Goossens, Eugeen Vanmechelen, Frederik Barkhof, Yolande AL Pijnenburg, Wiesje M van der Flier, Charlotte E Teunissen, Frode Berven, Pieter Jelle Visser
Alzheimer’s disease (AD) is heterogenous on the molecular level. Understanding this heterogeneity is critical for AD drug development. We aimed to define AD molecular subtypes by mass spectrometry proteomics in cerebrospinal fluid (CSF). Of the 386
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd6fc62a968d7b8d1ddc47a0f97f8c4
https://doi.org/10.1101/2023.05.10.23289793
https://doi.org/10.1101/2023.05.10.23289793
Autor:
Emma M Coomans, Jori Tomassen, Rik Ossenkoppele, Betty M Tijms, Luigi Lorenzini, Mara ten Kate, Lyduine E Collij, Fiona Heeman, Roos M Rikken, Sophie M van der Landen, Marijke E den Hollander, Sandeep S V Golla, Maqsood Yaqub, Albert D Windhorst, Frederik Barkhof, Philip Scheltens, Eco J C de Geus, Pieter Jelle Visser, Bart N M van Berckel, Anouk den Braber
Publikováno v:
Brain.
The amyloid cascade hypothesis has strongly impacted the Alzheimer's disease research agenda and clinical trial designs over the past decades, but precisely how amyloid-β pathology initiates the aggregation of neocortical tau remains unclear. We can