Functional Characterization of Murine Interferon Regulatory Factor 5 (IRF-5) and Its Role in the Innate Antiviral Response

Autor: Mumtaz Yaseen Balkhi, Katherine A. Fitzgerald, Paula M. Pitha, Carey L. Medin, Jorgen T. Reinert, Andrea Paun, Zhaozhao Jiang

Publikováno v: Paun, A, Reinert, T, Jiang, Z, Medin, C, Balkhi, M Y, Fitzgerald, K A & Pitha, P M 2008, ' Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response ', Journal of Biological Chemistry, vol. 283, no. 21, pp. 14295-308 . https://doi.org/10.1074/jbc.M800501200

Although the role of human IRF-5 in antiviral and inflammatory responses in vitro has been well characterized, much remains to be elucidated about murine IRF-5. Murine IRF-5, unlike the heavily spliced human gene, is primarily expressed as a full-len

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https://doi.org/10.1074/jbc.m800501200