Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jorgen Nelson"'
Autor:
Deborah Heydenburg Fuller, Merika Treants Koday, Jorgen Nelson, Aaron Chevalier, Michael Koday, Donald F. Smee, Amy L. Hartman, Douglas S. Reed, Kelly Stefano Cole, David Baker
Publikováno v:
Journal of Virus Eradication, Vol 2, Iss , Pp 8- (2016)
Externí odkaz:
https://doaj.org/article/2bbe1c2a46ec490a9087f3da6a144ba0
Autor:
Merika Treants Koday, Jorgen Nelson, Aaron Chevalier, Michael Koday, Hannah Kalinoski, Lance Stewart, Lauren Carter, Travis Nieusma, Peter S Lee, Andrew B Ward, Ian A Wilson, Ashley Dagley, Donald F Smee, David Baker, Deborah Heydenburg Fuller
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005409 (2016)
Broadly neutralizing antibodies targeting a highly conserved region in the hemagglutinin (HA) stem protect against influenza infection. Here, we investigate the protective efficacy of a protein (HB36.6) computationally designed to bind with high affi
Externí odkaz:
https://doaj.org/article/fd1ee080cfd1498393ace6eeda4b5e3c
Autor:
Nicole S. Clairmont, Tania Berrocal, Tanu Priya, Z. Beau Reneer, Avery Pong, Ted M. Ross, Matthew Walker, Yixuan J. Hou, Marsha L. Mason, Nuria Codina, Alexander Chen, Hong Peng, Luis M. Blancas-Mejia, Ryan Swanson, Jerry Chen, Tien-Ying Hsiang, Kevin Shengyang Yu, Michael Gale, Deborah H. Fuller, Carl Walkey, Jorgen Nelson, Renan Vergara, Anna Josephson-Day, Pamela J. Bjorkman, Wen Su, Daniel-Adriano Silva, Thomas W. Linsky, Ralph S. Baric, Masaya Mitsumoto, Hui-Ling Yen, Uland Y. Lau, Christopher O. Barnes, Javier Castellanos, Yu-Ru Lin, Katharina Esser-Nobis
Publikováno v:
Science (New York, N.y.)
Science
Science
A decoy to neutralize SARS-CoV-2 Many efforts to develop therapies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are focused on the interaction between the spike protein, which decorates the surface of the virus, and its host r
Autor:
Anna Josephson-Day, Katharina Esser-Nobis, Tien-Ying Hsiang, Luis M. Blancas-Mejia, Daniel-Adriano Silva, Uland Y. Lau, Tanu Priya, Nicole S. Clairmont, Carl Walkey, Ryan Swanson, Jorgen Nelson, Michael Gale, Avery Pong, Kevin Shengyang Yu, Tania Berrocal, Hong Peng, Hui-Ling Yen, Javier Castellanos, Wen Su, Thomas W. Linsky, Yu-Ru Lin, Nuria Codina, Alexander Chen, Renan Vergara, Masaya Mitsumoto, Ralph S. Baric, Yixuan J. Hou, Jerry Chen, Matthew Walker, Marsha L. Mason
Publikováno v:
bioRxiv
There is an urgent need for the ability to rapidly develop effective countermeasures for emerging biological threats, such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes the ongoing coronavirus disease 2019 (COVID-19)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898395e8cf9cfb1ee497f2a3224e8ad2
https://doi.org/10.1101/2020.08.03.231340
https://doi.org/10.1101/2020.08.03.231340
Autor:
Annie S. P. Yang, Carolina Barillas-Mury, Marlon Dillon, Rachel Vistein, Nicole Cavett, David Baker, Arne Schön, Monica W. Gerber, Robert W. Sauerwein, Reid B. Ballard, James O’Connor, Barbara J. Flynn, Alvaro Molina-Cruz, Jorgen Nelson, Fidel Zavala, Lawrence T. Wang, Robert A. Seder, Neville K. Kisalu, Amanda Fabra-García, Joseph R. Francica, Lais Pereira, Rogerio Amino, Bryan T. Mayer, Ian A. Cockburn, Neil P. King, Marie Pancera, Rosemarie D. Mason, Yevel Flores-Garcia, Raphael Gottardo, Azza H. Idris, Nicholas K. Hurlburt
Publikováno v:
Immunity, 53, 733-744.e8
Immunity
Immunity, 2020, 53 (4), pp.733-744.e8. ⟨10.1016/j.immuni.2020.08.014⟩
Immunity, 53, 4, pp. 733-744.e8
Immunity, Elsevier, 2020, 53 (4), pp.733-744.e8. ⟨10.1016/j.immuni.2020.08.014⟩
Immunity
Immunity, 2020, 53 (4), pp.733-744.e8. ⟨10.1016/j.immuni.2020.08.014⟩
Immunity, 53, 4, pp. 733-744.e8
Immunity, Elsevier, 2020, 53 (4), pp.733-744.e8. ⟨10.1016/j.immuni.2020.08.014⟩
International audience; Discovering potent human monoclonal antibodies (mAbs) targeting the Plasmodium falciparum circumsporozoite protein (PfCSP) on sporozoites (SPZ) and elucidating their mechanisms of neutralization will facilitate translation for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e2323b519a5419c4ded96d6aa53424
http://hdl.handle.net/2066/226211
http://hdl.handle.net/2066/226211
Autor:
Deborah H. Fuller, Rashmi Ravichandran, Peter Lee, Natalie K. Garcia, Kathryn A. Hooper, David Baker, Jorgen Nelson, David La, Ian A. Wilson, Caitlin E. Anderson, Andrew B. Ward, Eva-Maria Strauch, Steffen M. Bernard, Alan J. Bohn, William Sheffler, Jesse D. Bloom, Carly A. Holstein, Kelly K. Lee, Travis Nieusma, Paul Yager
Publikováno v:
Nature biotechnology
Many viral surface glycoproteins and cell surface receptors are homo-oligomers1-4, and hence can potentially be targeted by geometrically matched homo-oligomers that engage all subunits simultaneously to attain high avidity and/or lock subunits toget
Autor:
David Baker, Sagar D. Khare, Christine E. Tinberg, Lindsey Doyle, Kai Johnsson, Jorgen Nelson, Wojciech Jankowski, Charalampos G. Kalodimos, Alberto Schena, Jiayi Dou, Barry L. Stoddard
Publikováno v:
Nature. 501:212-216
The ability to design proteins with high affinity and selectivity for any given small molecule would have numerous applications in biosensing, diagnostics, and therapeutics, and is a rigorous test of our understanding of the physiochemical principles
Autor:
Jorgen Nelson, Merika Treants Koday, Amy L. Hartman, Kelly Stefano Cole, David Baker, Douglas S. Reed, Deborah H. Fuller, Donald F. Smee, Aaron Chevalier, Michael Koday
Publikováno v:
Journal of Virus Eradication, Vol 2, Iss, Pp 8-(2016)
Autor:
Peter Lee, Ashley Dagley, Aaron Chevalier, Merika Treants Koday, Hannah Kalinoski, Lauren Carter, David Baker, Ian A. Wilson, Deborah H. Fuller, Donald F. Smee, Michael Koday, Jorgen Nelson, Lance Stewart, Andrew B. Ward, Travis Nieusma
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 2, p e1005409 (2016)
PLoS Pathogens, Vol 12, Iss 2, p e1005409 (2016)
Broadly neutralizing antibodies targeting a highly conserved region in the hemagglutinin (HA) stem protect against influenza infection. Here, we investigate the protective efficacy of a protein (HB36.6) computationally designed to bind with high affi
Autor:
Jerrod J. Schwartz, Marc J. Lajoie, David Baker, Jorgen Nelson, Jay Shendure, Jason C. Klein, Eva-Maria Strauch
Publikováno v:
Nucleic Acids Research
While the cost of DNA sequencing has dropped by five orders of magnitude in the past decade, DNA synthesis remains expensive for many applications. Although DNA microarrays have decreased the cost of oligonucleotide synthesis, the use of array-synthe