Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jorgen Mould"'
Autor:
Christopher W. Vaughan, Richard J. Lewis, MacDonald J. Christie, S Aslan, David J. Adams, Mark D. Baker, Jorgen Mould, A Jayamanne, Roger Drinkwater, Jenny Ekberg, John N. Wood, Linda Thomas, Bjarke Abrahamsen
Publikováno v:
Proceedings of the National Academy of Sciences. 103:17030-17035
The tetrodotoxin-resistant voltage-gated sodium channel (VGSC) Na v 1.8 is expressed predominantly by damage-sensing primary afferent nerves and is important for the development and maintenance of persistent pain states. Here we demonstrate that μO-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d706f9efa6af90a27ea071ee66b0cab
https://doi.org/10.1073/pnas.0601819103
https://doi.org/10.1073/pnas.0601819103
Autor:
Jorgen Mould, Suzanne M. Curtis, Gerard P. Ahern, Suzy M. Pace, Angela F. Dulhunty, Pauline R. Junankar
Publikováno v:
The Journal of Physiology. 514:313-326
1. Ryanodine receptor (RyR) Ca2+ channels in the sarcoplasmic reticulum (SR) of skeletal muscle are regulated by the 12 kDa FK506- (or rapamycin-) binding protein (FKBP12). Rapamycin can also activate RyR channels with FKBP12 removed, suggesting that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862857af0f956fa9e95061a0a1f1de5e
https://doi.org/10.1111/j.1469-7793.1999.313ae.x
https://doi.org/10.1111/j.1469-7793.1999.313ae.x
Publikováno v:
Muscle & Nerve. 19:1025-1036
The experiments examine the effects of membrane potential on the time course of K+ contractures in small bundles of rat soleus and extensor digitorum longus (EDL) muscle fibers. Control K+ contractures were induced by exposure to a 200 mmol/L K+ solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5080a106cee7f732b85045402625a30
https://doi.org/10.1002/(sici)1097-4598(199608)19:8<1025::aid-mus10>3.0.co
https://doi.org/10.1002/(sici)1097-4598(199608)19:8<1025::aid-mus10>3.0.co
Autor:
Richard J. Lewis, Aaron M. Beedle, David J. Adams, Gerald W. Zamponi, Christina I. Schroeder, Clinton J. Doering, Jorgen Mould, Takahiro Yasuda
Publikováno v:
The Journal of biological chemistry. 279(33)
The omega-conotoxins from fish-hunting cone snails are potent inhibitors of voltage-gated calcium channels. The omega-conotoxins MVIIA and CVID are selective N-type calcium channel inhibitors with potential in the treatment of chronic pain. The beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc0530c9fdb80927eb1b1441f96d4dc
https://pubmed.ncbi.nlm.nih.gov/15166237
https://pubmed.ncbi.nlm.nih.gov/15166237
Autor:
Jorgen Mould, Angela F. Dulhunty
Publikováno v:
Pflugers Archiv : European journal of physiology. 440(1)
Transient "Cd2+ withdrawal" contractures, with amplitudes of ≤60% peak tetanic tension, were seen when ≥3 mM Cd2+ was removed, after exposures lasting ≥5 min, from solutions bathing rat soleus fibres at 22°C with Cl– as the major external an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4939560ad4f6739ab5c6cad2014c2a43
https://pubmed.ncbi.nlm.nih.gov/10863999
https://pubmed.ncbi.nlm.nih.gov/10863999