Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jorgen A. Mould"'
Autor:
Dharam Paul, Robert W. Gable, Jonathan B. Baell, Julia Cianci, Jorgen Alvar Mould, Andrew John Harvey, Bernard L. Flynn
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:2055-2061
Chalcone derivatives of the natural product khellinone were synthesised and screened for bioactivity against the voltage-gated potassium channel Kv1.3. X-ray crystallography was employed to investigate relationships between the structure and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab13faabf3e92d6105916af3c666366
https://doi.org/10.1016/j.bmcl.2008.01.099
https://doi.org/10.1016/j.bmcl.2008.01.099
Autor:
Lawrence H. Pinto, Yuki Ohigashi, Padma Venkataraman, Robert A. Lamb, Reay G. Paterson, Makoto Takeda, Jorgen A. Mould
Publikováno v:
Developmental Cell. 5:175-184
Successful uncoating of the influenza B virus in endosomes is predicted to require acidification of the interior of the virus particle. We report that a virion component, the BM2 integral membrane protein, when expressed in Xenopus oocytes or in mamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3204f8b379a94da4e0aef535bd6405
https://doi.org/10.1016/s1534-5807(03)00190-4
https://doi.org/10.1016/s1534-5807(03)00190-4
Autor:
U. Benjamin Kaupp, Jason E. Drury, Jorgen A. Mould, Stephan Frings, Andrew Pekosz, Kevin Shuck, Robert A. Lamb, Lawrence H. Pinto
Publikováno v:
International Congress Series. 1219:389-396
The use of oligomers comprised of amantadine-sensitive and -resistant forms demonstrated that the active oligomeric state of the channel is a tetramer. Cysteine scanning mutagenesis followed by evaluation of the ability of sulfhydryl-specific reagent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a9dd5d34e38366a9fa2388a79852e76
https://doi.org/10.1016/s0531-5131(01)00641-0
https://doi.org/10.1016/s0531-5131(01)00641-0
Autor:
U. Benjamin Kaupp, Stephan Frings, Lawrence H. Pinto, Andrew Pekosz, Robert A. Lamb, Jorgen A. Mould, Jason E. Drury
Publikováno v:
Journal of Biological Chemistry. 275:31038-31050
The M2 ion channel protein of influenza A virus is essential for mediating protein-protein dissociation during the virus uncoating process that occurs when the virus is in the acidic environment of the lumen of the secondary endosome. The difficulty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02428182228e12da75e3abbc9c48458
https://doi.org/10.1074/jbc.m003663200
https://doi.org/10.1074/jbc.m003663200
Autor:
Andrew Pekosz, Hui Chun Li, Lawrence H. Pinto, Robert A. Lamb, Christine S. Dudlak, James D. Lear, Jorgen A. Mould
Publikováno v:
The Journal of biological chemistry. 275(12)
The M(2) integral membrane protein of influenza A virus forms a proton-selective ion channel. We investigated the mechanism for proton transport of the M(2) protein in Xenopus oocytes using a two-electrode voltage clamp and in CV-1 cells using the wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253ca367ff62ebefa524cc8bee10edcf
https://pubmed.ncbi.nlm.nih.gov/10722698
https://pubmed.ncbi.nlm.nih.gov/10722698