Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Jorge del-Pozo"'
Autor:
Javier Moral-Sanz, Sophronia A. Lewis, Sandy MacMillan, Marco Meloni, Heather McClafferty, Benoit Viollet, Marc Foretz, Jorge del-Pozo, A. Mark Evans
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
AMPK modulates idiopathic and hypoxic pulmonary hypertension in adults, largely via unknown mechanisms. Here, the authors show that AMPK deficiency in smooth muscles causes persistent pulmonary hypertension of the new born and premature death in mice
Externí odkaz:
https://doaj.org/article/3376d21907c9443c9accb7061aa04379
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Chronic otitis media, inflammation of the middle ear, is a sequel to acute otitis media in ∼8% of children. Chronic otitis media with effusion is the most common cause of childhood deafness and is characterised by effusion of white blood cells into
Externí odkaz:
https://doaj.org/article/bb5cc17c00e242c3aa7b8d2fe32d560b
Autor:
David Collie, Steven H. Wright, Jorge del-Pozo, Elaine Kay, Tobias Schwarz, Magdalena Parys, Jessica Lawrence
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Lung is a dose-limiting organ in radiotherapy. This may limit tumour control when effort is made in planning to limit the likelihood of radiation-induced lung injury (RILI). Understanding the factors that dictate susceptibility to radiation-
Externí odkaz:
https://doaj.org/article/0c5d94e24c0d4d5098fd5b1fbe29f23e
Autor:
Carolina P. Moraleda, Diego Robledo, Alejandro P. Gutiérrez, Jorge del-Pozo, José M. Yáñez, Ross D. Houston
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Salmon Rickettsial Syndrome (SRS), caused by Piscirickettsia salmonis, is one of the primary causes of morbidity and mortality in Atlantic salmon aquaculture, particularly in Chile. Host resistance is a heritable trait, and functi
Externí odkaz:
https://doaj.org/article/6404cd38e98142c292834208baaeea96
Autor:
Jorge del-Pozo, Denis J. Headon, James D. Glover, Ali Azar, Sonia Schuepbach-Mallepell, Mahmood F. Bhutta, Jon Riddell, Scott Maxwell, Elspeth Milne, Pascal Schneider, Michael Cheeseman
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 3 (2022)
In mice, rats, dogs and humans, the growth and function of sebaceous glands and eyelid Meibomian glands depend on the ectodysplasin signalling pathway. Mutation of genes encoding the ligand EDA, its transmembrane receptor EDAR and the intracellular s
Externí odkaz:
https://doaj.org/article/6efcf17ea4b6497ab37681047ef17eb8
Autor:
Elspeth M. Milne, R. Scott Pirie, Caroline N. Hahn, Jorge del‐Pozo, Dawn Drummond, Sharon Moss, Bruce C. McGorum
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 5, Pp 2302-2311 (2019)
Abstract Background Equine dysautonomia (ED) causes degeneration and loss of autonomic neurons. Approximately 50% of chronic cases recover, but it is unclear how they survive neuronal loss. Objectives To assess lesions, autonomic neuron numbers, inte
Externí odkaz:
https://doaj.org/article/aec9dac9a7b14a7ab444d597f529853e
Autor:
Thao Thu Mai, Pattanapon Kayansamruaj, Chayanit Soontara, Pattarawit Kerddee, Dinh-Hung Nguyen, Saengchan Senapin, Janina Z. Costa, Jorge del-Pozo, Kim D. Thompson, Channarong Rodkhum, Ha Thanh Dong
Publikováno v:
Vaccines, Vol 10, Iss 2, p 167 (2022)
Tilapia lake virus (TiLV), a major pathogen of farmed tilapia, is known to be vertically transmitted. Here, we hypothesize that Nile tilapia (Oreochromis niloticus) broodstock immunized with a TiLV inactivated vaccine can mount a protective antibody
Externí odkaz:
https://doaj.org/article/9015e9a96f9f48259f804582d555cfcc
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 4 (2019)
Patients with mutations in the ectodysplasin receptor signalling pathway genes – the X-linked ligand ectodysplasin-A (EDA), the receptor EDAR or the receptor adapter EDARADD – have hypohidrotic ectodermal dysplasia (HED). In addition to having im
Externí odkaz:
https://doaj.org/article/ced1855e543343a8bacfa69e06142629
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 3 (2019)
Auditory bulla cavitation defects are a cause of otitis media, but the normal cellular pattern of bulla mesenchyme regression and its failure are not well understood. In mice, neural-crest-derived mesenchyme occupies the bulla from embryonic day 17.5
Externí odkaz:
https://doaj.org/article/3b9dea2e0970464fa5f72c5bac1da847
Autor:
Anna-Katarina Schilling, Charlotte Avanzi, Rainer G. Ulrich, Philippe Busso, Benoit Pisanu, Nicola Ferrari, Claudia Romeo, Maria Vittoria Mazzamuto, Joyce McLuckie, Craig M. Shuttleworth, Jorge Del-Pozo, Peter W. W. Lurz, Wendy G. Escalante-Fuentes, Jorge Ocampo-Candiani, Lucio Vera-Cabrera, Karen Stevenson, Jean-Louis Chapuis, Anna L. Meredith, Stewart T. Cole
Publikováno v:
Frontiers in Veterinary Science, Vol 6 (2019)
Eurasian red squirrels (Sciurus vulgaris) in the British Isles are the most recently discovered animal reservoir for the leprosy bacteria Mycobacterium leprae and Mycobacterium lepromatosis. Initial data suggest that prevalence of leprosy infection i
Externí odkaz:
https://doaj.org/article/53ba29402c7f4089aabbce43c7fbad41