Early neurotransmitters changes in prodromal frontotemporal dementia: A GENFI study

Autor: Enrico Premi, Marta Pengo, Irene Mattioli, Valentina Cantoni, Juergen Dukart, Roberto Gasparotti, Emanuele Buratti, Alessandro Padovani, Martina Bocchetta, Emily G. Todd, Arabella Bouzigues, David M. Cash, Rhian S. Convery, Lucy L. Russell, Phoebe Foster, David L. Thomas, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Jr, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Kamen A. Tsvetanov, Rik Vandenberghe, Elizabeth Finger, Pietro Tiraboschi, Alexandre de Mendonça, Isabel Santana, Chris R. Butler, Simon Ducharme, Alexander Gerhard, Johannes Levin, Markus Otto, Sandro Sorbi, Isabelle Le Ber, Florence Pasquier, Jonathan D. Rohrer, Barbara Borroni, Aitana Sogorb Esteve, Carolin Heller, Caroline V. Greaves, Henrik Zetterberg, Imogen J. Swift, Kiran Samra, Rachelle Shafei, Carolyn Timberlake, Thomas Cope, Timothy Rittman, Andrea Arighi, Chiara Fenoglio, Elio Scarpini, Giorgio Fumagalli, Vittoria Borracci, Giacomina Rossi, Giorgio Giaccone, Giuseppe Di Fede, Paola Caroppo, Sara Prioni, Veronica Redaelli, David Tang-Wai, Ekaterina Rogaeva, Miguel Castelo-Branco, Morris Freedman, Ron Keren, Sandra Black, Sara Mitchell, Christen Shoesmith, Robart Bartha, Rosa Rademakers, Jackie Poos, Janne M. Papma, Lucia Giannini, Rick van Minkelen, Yolande Pijnenburg, Benedetta Nacmias, Camilla Ferrari, Cristina Polito, Gemma Lombardi, Valentina Bessi, Michele Veldsman, Christin Andersson, Hakan Thonberg, Linn Öijerstedt, Vesna Jelic, Paul Thompson, Tobias Langheinrich, Albert Lladó, Anna Antonell, Jaume Olives, Mircea Balasa, Nuria Bargalló, Sergi Borrego-Ecija, Ana Verdelho, Carolina Maruta, Catarina B. Ferreira, Gabriel Miltenberger, Frederico Simões do Couto, Alazne Gabilondo, Ana Gorostidi, Jorge Villanua, Marta Cañada, Mikel Tainta, Miren Zulaica, Myriam Barandiaran, Patricia Alves, Benjamin Bender, Carlo Wilke, Lisa Graf, Annick Vogels, Mathieu Vandenbulcke, Philip Van Damme, Rose Bruffaerts, Koen Poesen, Pedro Rosa-Neto, Serge Gauthier, Agnès Camuzat, Alexis Brice, Anne Bertrand, Aurélie Funkiewiez, Daisy Rinaldi, Dario Saracino, Olivier Colliot, Sabrina Sayah, Catharina Prix, Elisabeth Wlasich, Olivia Wagemann, Sandra Loosli, Sonja Schönecker, Tobias Hoegen, Jolina Lombardi, Sarah Anderl-Straub, Adeline Rollin, Gregory Kuchcinski, Maxime Bertoux, Thibaud Lebouvier, Vincent Deramecourt, Beatriz Santiago, Diana Duro, Maria João Leitão, Maria Rosario Almeida, Miguel Tábuas-Pereira, Sónia Afonso

Publikováno v: Neurobiology of Disease, Vol 179, Iss , Pp 106068- (2023)

Background: Neurotransmitters deficits in Frontotemporal Dementia (FTD) are still poorly understood. Better knowledge of neurotransmitters impairment, especially in prodromal disease stages, might tailor symptomatic treatment approaches. Methods: In

Externí odkaz: https://doaj.org/article/90cd96a3a3cf4bd28acd0adf016bf6e5

Neurodegeneration trajectory in pediatric and adult/late DM1: A follow‐up MRI study across a decade

Autor: Garazi Labayru, Antonio Jimenez‐Marin, Esther Fernández, Jorge Villanua, Miren Zulaica, Jesus M. Cortes, Ibai Díez, Jorge Sepulcre, Adolfo López de Munain, Andone Sistiaga

Publikováno v: Annals of Clinical and Translational Neurology, Vol 7, Iss 10, Pp 1802-1815 (2020)

Abstract Objective To characterize the progression of brain structural abnormalities in adults with pediatric and adult/late onset DM1, as well as to examine the potential predictive markers of such progression. Methods 21 DM1 patients (pediatric ons

Externí odkaz: https://doaj.org/article/ddc95723d7164ed48c3aec884bef20d7

Differential early subcortical involvement in genetic FTD within the GENFI cohort

Autor: Martina Bocchetta, Emily G. Todd, Georgia Peakman, David M. Cash, Rhian S. Convery, Lucy L. Russell, David L. Thomas, Juan Eugenio Iglesias, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Alexandre de Mendonça, Isabel Santana, Chris R. Butler, Simon Ducharme, Alexander Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Sandro Sorbi, Isabelle Le Ber, Florence Pasquier, Jonathan D. Rohrer, Sónia Afonso, Maria Rosario Almeida, Sarah Anderl-Straub, Christin Andersson, Anna Antonell, Silvana Archetti, Andrea Arighi, Mircea Balasa, Myriam Barandiaran, Nuria Bargalló, Robart Bartha, Benjamin Bender, Alberto Benussi, Maxime Bertoux, Anne Bertrand, Valentina Bessi, Sandra Black, Sergi Borrego-Ecija, Jose Bras, Alexis Brice, Rose Bruffaerts, Agnès Camuzat, Marta Cañada, Valentina Cantoni, Paola Caroppo, Miguel Castelo-Branco, Olivier Colliot, Thomas Cope, Vincent Deramecourt, María de Arriba, Giuseppe Di Fede, Alina Díez, Diana Duro, Chiara Fenoglio, Camilla Ferrari, Catarina B. Ferreira, Nick Fox, Morris Freedman, Giorgio Fumagalli, Aurélie Funkiewiez, Alazne Gabilondo, Roberto Gasparotti, Serge Gauthier, Stefano Gazzina, Giorgio Giaccone, Ana Gorostidi, Caroline Greaves, Rita Guerreiro, Carolin Heller, Tobias Hoegen, Begoña Indakoetxea, Vesna Jelic, Hans-Otto Karnath, Ron Keren, Gregory Kuchcinski, Tobias Langheinrich, Thibaud Lebouvier, Maria João Leitão, Albert Lladó, Gemma Lombardi, Sandra Loosli, Carolina Maruta, Simon Mead, Lieke Meeter, Gabriel Miltenberger, Rick van Minkelen, Sara Mitchell, Katrina Moore, Benedetta Nacmias, Annabel Nelson, Jennifer Nicholas, Linn Öijerstedt, Jaume Olives, Sebastien Ourselin, Alessandro Padovani, Jessica Panman, Janne M. Papma, Yolande Pijnenburg, Cristina Polito, Enrico Premi, Sara Prioni, Catharina Prix, Rosa Rademakers, Veronica Redaelli, Daisy Rinaldi, Tim Rittman, Ekaterina Rogaeva, Adeline Rollin, Pedro Rosa-Neto, Giacomina Rossi, Martin Rossor, Beatriz Santiago, Dario Saracino, Sabrina Sayah, Elio Scarpini, Sonja Schönecker, Elisa Semler, Rachelle Shafei, Christen Shoesmith, Imogen Swift, Miguel Tábuas-Pereira, Mikel Tainta, Ricardo Taipa, David Tang-Wai, Paul Thompson, Hakan Thonberg, Carolyn Timberlake, Pietro Tiraboschi, Philip Van Damme, Mathieu Vandenbulcke, Michele Veldsman, Ana Verdelho, Jorge Villanua, Jason Warren, Carlo Wilke, Ione Woollacott, Elisabeth Wlasich, Henrik Zetterberg, Miren Zulaica

Publikováno v: NeuroImage: Clinical, Vol 30, Iss , Pp 102646- (2021)

Background: Studies have previously shown evidence for presymptomatic cortical atrophy in genetic FTD. Whilst initial investigations have also identified early deep grey matter volume loss, little is known about the extent of subcortical involvement,

Externí odkaz: https://doaj.org/article/c7e8cb1c48db46c6b63e1dd9db031d6c

White matter integrity changes and neurocognitive functioning in adult-late onset DM1: a follow-up DTI study

Autor: Jorge Villanua, Andone Sistiaga, Adolfo López de Munain, Jesus M. Cortes, Antonio Jimenez-Marin, Borja Camino-Pontes, Garazi Labayru, Joana Garmendia, Miren Zulaica

Publikováno v: Addi. Archivo Digital para la Docencia y la Investigación
instname

[EN] Myotonic Dystrophy Type 1 (DM1) is a multisystemic disease that affects gray and white matter (WM) tissues. WM changes in DM1 include increased hyperintensities and altered tract integrity distributed in a widespread manner. However, the precise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186cbae66a8e9bd573d863440900ddb2
https://doi.org/10.1038/s41598-022-07820-1

Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort

Autor: Rachelle Shafei, Benjamin Bender, Jackie M. Poos, Maria Carmela Tartaglia, Janne M. Papma, Lieke H.H. Meeter, Isabel Santana, Christen Shoesmith, Mikel Tainta, Simon Mead, Albert Lladó, Alazne Gabilondo, Emanuela Rotondo, Alexander Gerhard, Simon Ducharme, Myriam Barandiaran, Mario Masellis, Caroline V. Greaves, Jaume Olives, Rita Guerreiro, Andrea Arighi, Diana Duro NPsych, Sara Mitchell, Roberto Gasparotti, Mathieu Vandenbulcke, Tobias Langheinrich, Thomas E. Cope, Martina Bocchetta, Robart Bartha, Daid Tang-Wai, Jessica L. Panman, Maria Rosário Almeida, Christopher C Butler, Rose Bruffaerts, Núria Bargalló, Pietro Tiraboschi, Beatriz Santiago, Elisabeth Wlasich, Philip Vandamme, Giorgio Giaccone, Sergi Borrego-Écija, Sonja Schönecker, Robert Laforce, Paola Caroppo, Katrina M. Moore, Ione O.C. Woollacott, Maria de Arriba, Veronica Redaelli, Rick van Minkelen, Jorge Villanua, Sónia Afonso, Matthis Synofzik, Nick C. Fox, Jennifer M. Nicholas, David L. Thomas, James B. Rowe, Carlo Wilke, Miren Zulaica, Pedro Rosa-Neto, Jonathan D. Rohrer, Elizabeth Finger, Carolyn Timberlake, C. Ferreira, David M. Cash, Timothy Rittman, Alessandro Padovani, Barbara Borroni, Ricardo Taipa, John C. van Swieten, Sandra V. Loosli, Begoña Indakoetxea, Daniela Galimberti, Sandra E. Black, Ana Gorostidi, Vesna Jelic, Catharina Prix, Ron Keren, Y.A.L. Pijnenburg, Michele Veldsman, Rosa Rademakers, Adrian Danek, Zigor Diaz, Miguel Tábuas-Pereira, Johannes Levin, Raquel Sánchez-Valle, Jose Bras, Rhian S Convery, Silvana Archetti, Markus Otto, Miguel Castelo-Branco, Rik Vandenberghe, Anna Antonell, Fabrizio Tagliavini, Sarah Anderl-Straub, Giuseppe Di Fede, Martin N. Rossor, Carolina Maruta MPsych, Enrico Premi, Giorgio G. Fumagalli, Sara Prioni, Cristina Muscio, Maria João Leitão, Lucy L. Russell, Håkan Thonberg, Ana Verdelho, Gabriel Miltenberger, Ekaterina Rogaeva, Giacomina Rossi, Linn Öijerstedt, Christin Andersson, Caroline Graff, Serge Gauthier, Maura Cosseddu MPsych, Carolin Heller, Stefano Gazzina, Jason D. Warren, Chiara Fenoglio, Tobias Hoegen, Elio Scarpini, Morris Freedman, Fermin Moreno, Mircea Balasa, Lize C. Jiskoot, Alexandre de Mendonça, Paul Thompson, Elisa Semler, Hans-Otto Karnarth

Publikováno v: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Cortex 133, 384-398 (2020). doi:10.1016/j.cortex.2020.08.023
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Genetic FTD Initiative (GENFI) 2020, ' Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort ', Cortex, vol. 133, pp. 384-398 . https://doi.org/10.1016/j.cortex.2020.08.023
Cortex, 133, 384-398. Masson SpA
Russell, L L, Greaves, C V, Bocchetta, M, Nicholas, J, Convery, R S, Moore, K, Cash, D M, van Swieten, J, Jiskoot, L, Moreno, F, Sanchez-Valle, R, Borroni, B, Laforce, R, Masellis, M, Tartaglia, M C, Graff, C, Rotondo, E, Galimberti, D, Rowe, J B, Finger, E, Synofzik, M, Vandenberghe, R, de Mendonça, A, Tagliavini, F, Santana, I, Ducharme, S, Butler, C, Gerhard, A, Levin, J, Danek, A, Otto, M, Warren, J D, Rohrer, J D, Rossor, M N, Fox, N C, Woollacott, I O C, Shafei, R, Heller, C, Guerreiro, R, Bras, J, Thomas, D L, Mead, S, Meeter, L, Panman, J, Papma, J, Poos, J, van Minkelen, R, Pijnenburg, Y, Barandiaran, M, Indakoetxea, B, Gabilondo, A, Tainta, M, de Arriba, M, Gorostidi, A, Zulaica, M, Villanua, J, Diaz, Z, Borrego-Ecija, S, Olives, J, Lladó, A, Balasa, M, Antonell, A, Bargallo, N, Premi, E, Cosseddu MPsych, M, Gazzina, S, Padovani, A, Gasparotti, R, Archetti, S, Black, S, Mitchell, S, Rogaeva, E, Freedman, M, Keren, R, Tang-Wai, D, Öijerstedt, L, Andersson, C, Jelic, V, Thonberg, H, Arighi, A, Fenoglio, C, Scarpini, E, Fumagalli, G, Cope, T, Timberlake, C, Rittman, T, Shoesmith, C, Bartha, R, Rademakers, R, Wilke, C, Karnarth, H-O, Bender, B, Bruffaerts, R, Vandamme, P, Vandenbulcke, M, Ferreira, C B, Miltenberger, G, Maruta MPsych, C, Verdelho, A, Afonso, S N, Taipa, R, Caroppo, P, di Fede, G, Giaccone, G, Muscio, C, Prioni, S, Redaelli, V, Rossi, G, Tiraboschi, P, Duro NPsych, D, Almeida, M R, Castelo-Branco, M, Leitão, M J, Tabuas-Pereira, M, Santiago, B, Gauthier, S, Rosa-Neto, P, Veldsman, M, Thompson, P, Langheinrich, T, Prix, C, Hoegen, T, Wlasich, E, Loosli, S, Schonecker, S, the Genetic FTD Initiative, GENFI, Semler, E & Anderl-Straub, S 2020, ' Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort ', Cortex, vol. 133, pp. 384-398 . https://doi.org/10.1016/j.cortex.2020.08.023
Medical Biophysics Publications

© 2020 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
A key symptom of frontotemporal dementia (FTD) is difficulty interacting socially with others

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f473ba7ad713c07f0bee456df92fa2
http://europepmc.org/articles/PMC7754789