Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Jorge Simón"'
Autor:
Irene González-Recio, Jorge Simón, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, Maria Mercado-Gómez, Rubén Rodríguez-Agudo, Sofía Lachiondo-Ortega, Clàudia Gil-Pitarch, Carmen Fernández-Rodríguez, Donatello Castellana, Maria U. Latasa, Leticia Abecia, Juan Anguita, Teresa C. Delgado, Paula Iruzubieta, Javier Crespo, Serge Hardy, Petar D. Petrov, Ramiro Jover, Matías A. Avila, César Martín, Ute Schaeper, Michel L. Tremblay, James W. Dear, Steven Masson, Misti Vanette McCain, Helen L. Reeves, Raul J. Andrade, M. Isabel Lucena, Daniela Buccella, Luis Alfonso Martínez-Cruz, Maria L Martínez-Chantar
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Drug induced liver injury (DILI) is an important cause acute liver failure. Here the authors report that serum Mg2+ serum levels decrease in patients with DILI as well as in preclinical animal models treated with acetaminophen overdose, and that earl
Externí odkaz:
https://doaj.org/article/2a4712610b65483485edb1bca7bf6fb0
Autor:
Gustavo Vera-Reveles, Jorge Simón, Edgar Briones, José Manuel Gutiérrez-Hernández, Francisco J. González, Gabriel González, Edmundo Cerda-Rodríguez, José Vulfrano González-Fernández
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract A biomaterial made of coir and Multi-Walled Carbon Nanotubes (MWCNTs) is presented which exhibits a relatively high-Temperature Coefficient of Resistance (TCR) and thermal insulation properties. Bolometers usually offer acceptable thermal is
Externí odkaz:
https://doaj.org/article/c52727a7475b4e6890ea365629374e53
Autor:
Maria Mercado-Gómez, Endika Prieto-Fernández, Naroa Goikoetxea-Usandizaga, Laura Vila-Vecilla, Mikel Azkargorta, Miren Bravo, Marina Serrano-Maciá, Leire Egia-Mendikute, Rubén Rodríguez-Agudo, Sofia Lachiondo-Ortega, So Young Lee, Alvaro Eguileor Giné, Clàudia Gil-Pitarch, Irene González-Recio, Jorge Simón, Petar Petrov, Ramiro Jover, Luis Alfonso Martínez-Cruz, June Ereño-Orbea, Teresa Cardoso Delgado, Felix Elortza, Jesús Jiménez-Barbero, Ruben Nogueiras, Vincent Prevot, Asis Palazon, María L. Martínez-Chantar
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
SARS-CoV-2 pseudovirus infects human hepatocytes leading to metabolic reprogramming towards glycolysis and impaired mitochondrial activity, and metformin can reduce infection under steatotic conditions.
Externí odkaz:
https://doaj.org/article/3f2d0b36718146559a8c005f572704c4
Autor:
Francisco R. Castillo-Soria, J. Alberto Del Puerto-Flores, Cesar A. Azurdia-Meza, Vinoth Babu Kumaravelu, Jorge Simón, Carlos A. Gutierrez
Publikováno v:
Future Internet, Vol 15, Iss 9, p 299 (2023)
This paper presents two precoding techniques for a reconfigurable intelligent surface (RIS)-assisted multi-user (MU) multiple-input multiple-output (MIMO) double quadrature spatial modulation (DQSM) downlink transmission system. Instead of being appl
Externí odkaz:
https://doaj.org/article/435a77aea14146aeb7d0b8ba5752c0bd
Autor:
Pablo Fernández-Tussy, Rubén Rodríguez-Agudo, David Fernández-Ramos, Lucía Barbier-Torres, Imanol Zubiete-Franco, Sergio López de Davalillo, Elisa Herraez, Naroa Goikoetxea-Usandizaga, Sofia Lachiondo-Ortega, Jorge Simón, Fernando Lopitz-Otsoa, Virginia Gutiérrez-de Juan, Misti V. McCain, Maria J. Perugorria, Jon Mabe, Nicolás Navasa, Cecilia M. P. Rodrigues, Isabel Fabregat, Loreto Boix, Victor Sapena, Juan Anguita, Shelly C. Lu, José M. Mato, Jesus M. Banales, Erica Villa, Helen L. Reeves, Jordi Bruix, Maria Reig, Jose J. G. Marin, Teresa C. Delgado, María L. Martínez-Chantar
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-16 (2021)
Abstract Dysregulation of miRNAs is a hallmark of cancer, modulating oncogenes, tumor suppressors, and drug responsiveness. The multi-kinase inhibitor sorafenib is one of the first-line drugs for advanced hepatocellular carcinoma (HCC), although the
Externí odkaz:
https://doaj.org/article/fb7ef154614446039d3b36ccb14472c8
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Chronic liver diseases include a broad group of hepatic disorders from different etiologies and with varying degrees of progression and severity. Among them, non-alcoholic fatty (NAFLD) and alcoholic (ALD) liver diseases are the most frequent forms o
Externí odkaz:
https://doaj.org/article/330641f91fdd487ca0b9b237d3ac3135
Autor:
Francisco R. Castillo-Soria, Carlos A. Gutierrez, Abel García-Barrientos, Armando Arce-Casas, Jorge Simón
Publikováno v:
EURASIP Journal on Wireless Communications and Networking, Vol 2020, Iss 1, Pp 1-14 (2020)
Abstract This paper presents three multiuser multiple input-multiple output (MU-MIMO) downlink transmission strategies based on the extended quadrature spatial modulation (EQSM) system for mobile communication. The three MU-MIMO precoding strategies
Externí odkaz:
https://doaj.org/article/0a2e5f4c8a7e46d2baa415128e273ff7
Autor:
Marina Serrano-Maciá, Jorge Simón, Maria J. González-Rellan, Mikel Azkargorta, Naroa Goikoetxea-Usandizaga, Fernando Lopitz-Otsoa, Diego Saenz De Urturi, Rubén Rodríguez-Agudo, Sofia Lachiondo-Ortega, Maria Mercado-Gomez, Virginia Gutiérrez de Juan, Maider Bizkarguenaga, David Fernández-Ramos, Xabier Buque, Guido A. Baselli, Luca V.C. Valenti, Paula Iruzubieta, Javier Crespo, Erica Villa, Jesus M. Banales, Matias A. Avila, Jose J.G. Marin, Patricia Aspichueta, James Sutherland, Rosa Barrio, Ugo Mayor, Félix Elortza, Dimitris P. Xirodimas, Rubén Nogueiras, Teresa C. Delgado, María Luz Martínez-Chantar
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101275- (2021)
Objective: Neddylation is a druggable and reversible ubiquitin-like post-translational modification upregulated in many diseases, including liver fibrosis, hepatocellular carcinoma, and more recently, non-alcoholic fatty liver disease (NAFLD). Herein
Externí odkaz:
https://doaj.org/article/358512f74108488aa4daf723e0bda944
Autor:
Pablo Fernández-Tussy, David Fernández-Ramos, Fernando Lopitz-Otsoa, Jorge Simón, Lucía Barbier-Torres, Beatriz Gomez-Santos, Maitane Nuñez-Garcia, Mikel Azkargorta, Virginia Gutiérrez-de Juan, Marina Serrano-Macia, Rubén Rodríguez-Agudo, Paula Iruzubieta, Juan Anguita, Rui E. Castro, Devin Champagne, Mercedes Rincón, Felix Elortza, Anita Arslanow, Marcin Krawczyk, Frank Lammert, Mélanie Kirchmeyer, Iris Behrmann, Javier Crespo, Shelly C. Lu, José M. Mato, Marta Varela-Rey, Patricia Aspichueta, Teresa C. Delgado, María L. Martínez-Chantar
Publikováno v:
Molecular Metabolism, Vol 29, Iss , Pp 40-54 (2019)
Objective: Non-alcoholic fatty liver disease (NAFLD) is a complex pathology in which several dysfunctions, including alterations in metabolic pathways, mitochondrial functionality and unbalanced lipid import/export, lead to lipid accumulation and pro
Externí odkaz:
https://doaj.org/article/a17e13bf601849f78b91e8ef169b6cb2
Autor:
Rubén Rodríguez-Agudo, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, Pablo Fernández-Tussy, David Fernández-Ramos, Sofía Lachiondo-Ortega, Irene González-Recio, Clàudia Gil-Pitarch, María Mercado-Gómez, Laura Morán, Maider Bizkarguenaga, Fernando Lopitz-Otsoa, Petar Petrov, Miren Bravo, Sebastiaan Martijn Van Liempd, Juan Manuel Falcon-Perez, Amaia Zabala-Letona, Arkaitz Carracedo, Jose Vicente Castell, Ramiro Jover, Luis Alfonso Martínez-Cruz, Teresa Cardoso Delgado, Francisco Javier Cubero, María Isabel Lucena, Raúl Jesús Andrade, Jon Mabe, Jorge Simón, María Luz Martínez-Chantar
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 897 (2022)
Drug-induced liver injury (DILI) development is commonly associated with acetaminophen (APAP) overdose, where glutathione scavenging leads to mitochondrial dysfunction and hepatocyte death. DILI is a severe disorder without effective late-stage treat
Externí odkaz:
https://doaj.org/article/2ad42c57fdeb4f66bad2d0eabf53b813