Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jorge Rubén Cabrera"'
Autor:
Guorong Sun, Kai Alexander Kropp, Marieluise Kirchner, Nina Plückebaum, Anton Selich, Manutea Serrero, Akshay Dhingra, Jorge Rubén Cabrera, Birgit Ritter, Rudolf Bauerfeind, Emanuel Wyler, Markus Landthaler, Axel Schambach, Beate Sodeik, Philipp Mertins, Abel Viejo-Borbolla
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT The highly prevalent herpes simplex virus type 1 (HSV-1) causes a range of diseases, including cold sores, blinding keratitis, and life-threatening encephalitis. HSV-1 initially replicates in epithelial cells, enters the peripheral nervous s
Externí odkaz:
https://doaj.org/article/b03f18e16aa44eca859b26cb7c0b5163
Autor:
Jorge Rubén Cabrera, Ignacio Rodríguez-Izquierdo, José Luis Jiménez, María Ángeles Muñoz-Fernández
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Genetics have provided hints on potential molecular pathways involved in neurodegenerative diseases (NDD). However, the number of cases caused exclusively by genetic alterations is low, suggesting an important contribution of envi
Externí odkaz:
https://doaj.org/article/47a2c65c602b4186a140b30028819adf
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/ef6d044d1ece42b78ea1d26afe6e6410
Autor:
Jorge Rubén Cabrera, Abel Viejo-Borbolla, Nadia Martinez-Martín, Soledad Blanco, Francisco Wandosell, Antonio Alcamí
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004571 (2015)
Herpes simplex virus type 1 (HSV-1) and HSV-2 are highly prevalent viruses that cause a variety of diseases, from cold sores to encephalitis. Both viruses establish latency in peripheral neurons but the molecular mechanisms facilitating the infection
Externí odkaz:
https://doaj.org/article/39495cf757734b5287aed600be702135
Autor:
José J. Lucas, Vega García-Escudero, Ivó H. Hernández, Jorge Rubén Cabrera, Félix Hernández, Daniel Ruiz-Gabarre, Mar Pérez, Ricardo Gargini, Raquel Cuadros, Esther García, Jesús Avila, Ramón García-Escudero
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Acta Neuropathologica
Digital.CSIC. Repositorio Institucional del CSIC
instname
Instituto de Salud Carlos III (ISCIII)
Acta Neuropathologica
Digital.CSIC. Repositorio Institucional del CSIC
instname
Tauopathies, including Alzheimer’s disease (AD) and frontotemporal lobar degeneration with Tau pathology (FTLD-tau), are a group of neurodegenerative disorders characterized by Tau hyperphosphorylation. Post-translational modifications of Tau such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bd822606c623f2e28ef9f6dc66f1b7
https://hdl.handle.net/20.500.12105/13214
https://hdl.handle.net/20.500.12105/13214
Autor:
Audra J. Charron, Sean A. Taylor, Stacey Cerón, Richard Manivanh, Scott A. Gerber, Jesse Mehrbach, Jorge Rubén Cabrera, David A. Leib, Andrew V. Grassetti
Publikováno v:
J Virol
Expression of viral genes and activation of innate antiviral responses during infection result in an increase in reactive oxygen species (ROS) and toxic by-products of energy metabolism which can lead to cell death. The mitochondrion and its associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73c82384f11518ef1b0dbc8f78c5798
https://doi.org/10.1128/jvi.01784-19
https://doi.org/10.1128/jvi.01784-19
Autor:
Manuel Sánchez-Martín, Belén Pintado, José J. Lucas, Maria Jose Perez-Alvarez, Ramón García-Escudero, Verónica Domínguez, Ivó H. Hernández, María Santos-Galindo, Jorge Rubén Cabrera
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The Author(s) (2020).
Huntington’s disease and X-linked dystonia parkinsonism are two monogenic basal ganglia model diseases. Huntington’s disease is caused by a polyglutamine-encoding CAG repeat expansion in the Huntingtin (HTT) gene leadin
Huntington’s disease and X-linked dystonia parkinsonism are two monogenic basal ganglia model diseases. Huntington’s disease is caused by a polyglutamine-encoding CAG repeat expansion in the Huntingtin (HTT) gene leadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c9d15d5e10c30c8d231053363eaed7
http://hdl.handle.net/10261/229569
http://hdl.handle.net/10261/229569
Publikováno v:
mBio, Vol 10, Iss 2, p e02567-18 (2019)
mBio, Vol 10, Iss 2 (2019)
mBio
mBio, Vol 10, Iss 2 (2019)
mBio
Neurons rely on IFNs and autophagy as major defenses against viral infections, and HSV must overcome such defenses in order to replicate. In addition to controlling host immunity, HSV must also control host membranes in order to complete its life cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c28fcb11790805734eba3b701ada6f
https://doaj.org/article/b53ea99b11424c51af214e1e34049211
https://doaj.org/article/b53ea99b11424c51af214e1e34049211
Autor:
Ivó H. Hernández, José J. Lucas, Marta Fernández-Nogales, María Santos-Galindo, Jorge Rubén Cabrera
Publikováno v:
Brain Pathology. 26:772-778
Huntington's disease (HD) is caused by a CAG-repeat encoding a polyglutamine (polyQ) tract in the huntingtin protein. There is plenty of evidence of polyQ-driven toxicity. However, CAG repeat RNA-driven alteration of splicing has recently been propos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dd7a4c12474bd3fab287743cc56200c
https://doi.org/10.1111/bpa.12430
https://doi.org/10.1111/bpa.12430
Autor:
Jorge Rubén Cabrera, José J. Lucas
Publikováno v:
Brain Pathology. 27:181-189
Dendritic alteration of striatal medium spiny neurons is one of the earliest morphological abnormalities in Huntington's disease (HD). The main microtubule-associated protein in dendrites is MAP2. The low-molecular weight isoforms of MAP2 (LMW-MAP2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b031bc1aebb51e451ce83ec66e600ab0
https://doi.org/10.1111/bpa.12387
https://doi.org/10.1111/bpa.12387