Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jorge Romo-Tena"'
Autor:
Nathan Richoz, Zewen K. Tuong, Kevin W. Loudon, Eduardo Patiño-Martínez, John R. Ferdinand, Jorge Romo-Tena, Anaïs Portet, Kathleen R. Bashant, Emeline Thevenon, Francesca Rucci, Thomas Hoyler, Tobias Junt, Mariana J. Kaplan, Richard M. Siegel, Menna R. Clatworthy
Publikováno v:
JCI Insight, Vol 7, Iss 21 (2023)
Lupus nephritis is a serious complication of systemic lupus erythematosus, mediated by IgG immune complex (IC) deposition in kidneys, with limited treatment options. Kidney macrophages are critical tissue sentinels that express IgG-binding Fcγ recep
Externí odkaz:
https://doaj.org/article/d738063f70d840b2bb17022567be68e4
Publikováno v:
Journal of Investigative Dermatology. 142:823-833
Dysregulation in the phenotype and function of neutrophils may play important roles in the initiation and perpetuation of autoimmune responses, including conditions affecting the skin. Neutrophils can have local and systemic effects on innate and ada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d5e4674c6ce49e76a28a468f470278
https://doi.org/10.1016/j.jid.2021.04.014
https://doi.org/10.1016/j.jid.2021.04.014
Autor:
Luz P. Blanco, Hong-Wei Sun, Philip M. Carlucci, Jorge Romo-Tena, Mariana J. Kaplan, Xinghao Wang, Markus Hafner, José J. Torres-Ruíz
Publikováno v:
Arthritis Rheumatol
OBJECTIVE Neutrophil extracellular traps (NETs) are extracellular lattices composed of nucleic material bound to neutrophil granule proteins. NETs may play pathogenic roles in the development and severity of autoimmune diseases such as systemic lupus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a851175ee4ff314e88384d773b2a3cd
https://europepmc.org/articles/PMC8589882/
https://europepmc.org/articles/PMC8589882/
Autor:
Jorge Romo-Tena, Mariana J. Kaplan
Publikováno v:
Current opinion in rheumatology. 32(6)
Purpose of review To provide an update on state-of-the-art evidence on the role of immunometabolism reprogramming in the pathogenesis of systemic lupus erythematosus (SLE). Recent findings Mitochondrial dysfunction and enhanced oxidative stress, alon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49984066981761c9595e2eb53722b815
https://pubmed.ncbi.nlm.nih.gov/32826478
https://pubmed.ncbi.nlm.nih.gov/32826478
Autor:
Jorge Romo-Tena, Diana Gómez-Martín, Sandra Rajme-López, Jorge Alcocer-Varela, Luis Aparicio-Vera
Publikováno v:
Clinical and Experimental Immunology. 191:42-49
Summary T cells from systemic lupus erythematosus (SLE) patients display a wide array of anomalies in peripheral immune tolerance mechanisms. The role of ubiquitin ligases such as Cbl-b has been described recently in these phenomena. However, its rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170d78d07d9ca155becd25ce14379fa9
https://doi.org/10.1111/cei.13054
https://doi.org/10.1111/cei.13054
Autor:
Luz P. Blanco, Jorge Alcocer-Varela, Diana Gómez-Martín, Jorge Romo-Tena, Mariana J. Kaplan, R. Carazo-Vargas, Carmelo Carmona-Rivera
Publikováno v:
FRIDAY, 15 JUNE 2018.
Background SLE patients display an elevated cardiovascular risk when compared to the general population.1 Interferon-alpha (IFN-α) appears to drive atherogenesis in SLE at least in part, by promoting abnormal phenotype and function of EPCs.1 S1P1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45cd2c009d9df71678f8fd1da0894401
https://doi.org/10.1136/annrheumdis-2018-eular.3577
https://doi.org/10.1136/annrheumdis-2018-eular.3577
Autor:
Jorge Romo-Tena, Isaac Bartnicki-Navarrete, Diana Gómez-Martín, Jorge Alcocer-Varela, Roberto Reyna-de la Garza
Publikováno v:
Clinical rheumatology. 37(11)
The primary aim of this study was to assess demographic, clinical, and serological factors associated with remission in systemic lupus erythematosus (SLE). A retrospective cohort study was performed. We examined relevant features in patients with SLE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7065efed775743f59b31cf7c4be89a84
https://pubmed.ncbi.nlm.nih.gov/30056524
https://pubmed.ncbi.nlm.nih.gov/30056524
Autor:
F Espinosa-Ortega, P Villaseñor-Ovies, Diana Gómez-Martín, K Santana-De Anda, Jorge Romo-Tena, Jorge Alcocer-Varela
Publikováno v:
Clinical and Experimental Immunology. 179:520-528
Summary The role of T cells in idiopathic inflammatory myopathies (IIM) is not yet clear. Some alterations in certain subsets have been reported in inflamed muscle cells. However, a broad quantitative assessment of peripheral T cell subsets has not b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69a630957d3719b8eb7ba0d45ac6cfe
https://doi.org/10.1111/cei.12475
https://doi.org/10.1111/cei.12475
Autor:
Guillermo Juárez-Vega, Eucario León-Rodríguez, Diana Gómez-Martín, Monica M. Rivera-Franco, Jorge Alcocer-Varela, Jorge Romo-Tena, Javier Merayo-Chalico
Publikováno v:
Leukemia research. 63
Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). At our Institution, patients transplanted using G-CSF-primed bone marrow (G-BM), have a lower incidence of GVHD when compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523d60696decb04430ee7cc27ceeb904
https://pubmed.ncbi.nlm.nih.gov/29101827
https://pubmed.ncbi.nlm.nih.gov/29101827
Publikováno v:
Autoimmunity Reviews. 12:1171-1176
Cytotoxic T-Lymphocye Antigen 4 (CTLA-4) or CD152 is an inhibitory molecule that plays a critical role in maintenance of tolerance to self-antigens. CTLA-4 is structurally as well as functionally related to CD28, since it shares 31% of homology and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cf7972e63889b8a0b32da0caea31bb
https://doi.org/10.1016/j.autrev.2013.07.002
https://doi.org/10.1016/j.autrev.2013.07.002