Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jorge Ripoll-Gómez"'
Autor:
Jose M. Honrubia, Jose R. Valverde, Diego Muñoz-Santos, Jorge Ripoll-Gómez, Nuria de la Blanca, Jorge Izquierdo, Marta Villarejo-Torres, Ana Marchena-Pasero, María Rueda-Huélamo, Ivan Nombela, Mercedes Ruiz-Yuste, Sonia Zuñiga, Isabel Sola, Luis Enjuanes
Publikováno v:
Viruses, Vol 16, Iss 8, p 1214 (2024)
The interaction between SARS-CoV PDZ-binding motifs (PBMs) and cellular PDZs is responsible for virus virulence. The PBM sequence present in the 3a and envelope (E) proteins of SARS-CoV can potentially bind to over 400 cellular proteins containing PD
Externí odkaz:
https://doaj.org/article/46ba8b5748c848e3b5f47b5fef069122
Autor:
Luis Enjuanes, Isabel Sola, Sonia Zúñiga, José M. Honrubia, Melissa Bello-Pérez, Alejandro Sanz-Bravo, Ezequiel González-Miranda, Jesús Hurtado-Tamayo, Ricardo Requena-Platek, Li Wang, Diego Muñoz-Santos, Carlos M. Sánchez, Ana Esteban, Jorge Ripoll-Gómez
Publikováno v:
Current Research in Immunology, Vol 3, Iss , Pp 151-158 (2022)
Coronaviruses (CoVs) have the largest genome among RNA viruses and store large amounts of information without genome integration as they replicate in the cell cytoplasm. The replication of the virus is a continuous process, whereas the transcription
Externí odkaz:
https://doaj.org/article/e04daf16ecae41259caffc07dcb5dc21
Autor:
Jose M. Honrubia, Javier Gutierrez-Álvarez, Alejandro Sanz-Bravo, Ezequiel González-Miranda, Diego Muñoz-Santos, Carlos Castaño-Rodriguez, Li Wang, Marta Villarejo-Torres, Jorge Ripoll-Gómez, Ana Esteban, Raul Fernandez-Delgado, Pedro José Sánchez-Cordón, Juan Carlos Oliveros, Stanley Perlman, Paul B. McCray, Isabel Sola, Luis Enjuanes
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Coronaviruses (CoVs) of genera α, β, γ, and δ encode proteins that have a PDZ-binding motif (PBM) consisting of the last four residues of the envelope (E) protein (PBM core). PBMs may bind over 400 cellular proteins containing PDZ domain
Externí odkaz:
https://doaj.org/article/748cab695f5f46f68ab0f4651f18e0e3
Autor:
Li Wang, María Guzman, Diego Muñoz-Santos, Jose Manuel Honrubia, Jorge Ripoll-Gomez, Rafael Delgado, Isabel Sola, Luis Enjuanes, Sonia Zuñiga
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Engineering of reverse genetics systems for newly emerged viruses allows viral genome manipulation, being an essential tool for the study of virus life cycle, virus-host interactions and pathogenesis, as well as for the development of effective antiv
Externí odkaz:
https://doaj.org/article/523585cd5a3a42a6a426c819267f7999
Publikováno v:
European Journal of Neuroscience. 33:1252-1255
Glutamate is the major excitatory neurotransmitter of the central nervous system in vertebrates. Excitotoxicity, caused by over-stimulation of the glutamate receptors, is a major cause of neuron death in several brain diseases, including epilepsy. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::596f476a408684dfb9e202feea4ad1c7
https://doi.org/10.1111/j.1460-9568.2011.07622.x
https://doi.org/10.1111/j.1460-9568.2011.07622.x
Publikováno v:
Zebrafish. 5:323-333
The zebrafish (Danio rerio) is rapidly gaining ground as a disease model. However, until now, the use of this species with human pathogens has been restricted to just three bacteria; no studies involving viruses that infect humans are recorded. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eded0b84911349b3166f7bd41d4f261
https://doi.org/10.1089/zeb.2008.0552
https://doi.org/10.1089/zeb.2008.0552
Publikováno v:
The European journal of neuroscience. 33(7)
Glutamate is the major excitatory neurotransmitter of the central nervous system in vertebrates. Excitotoxicity, caused by over-stimulation of the glutamate receptors, is a major cause of neuron death in several brain diseases, including epilepsy. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::406a253b63c6fff85dd50bc2f83c643f
https://pubmed.ncbi.nlm.nih.gov/21375600
https://pubmed.ncbi.nlm.nih.gov/21375600
Autor:
Luis Enjuanes, Isabel Sola, Sonia Zúñiga, José M. Honrubia, Melissa Bello-Pérez, Alejandro Sanz-Bravo, Ezequiel González-Miranda, Jesús Hurtado-Tamayo, Ricardo Requena-Platek, Li Wang, Diego Muñoz-Santos, Carlos M. Sánchez, Ana Esteban, Jorge Ripoll-Gómez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Curr Res Immunol.
instname
Curr Res Immunol.
Coronaviruses (CoVs) have the largest genome among RNA viruses and store large amounts of information without genome integration as they replicate in the cell cytoplasm. The replication of the virus is a continuous process, whereas the transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9a328f40e364d4115a21e16d5c1ce6