Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jorge R Polanco"'
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231212 (2020)
Two major proteolytic systems, the proteasome and the autophagy pathway, are key components of the proteostasis network. The immunoproteasome, a proteasome subtype, and autophagy are upregulated under stress conditions, forming a coordinated unit des
Externí odkaz:
https://doaj.org/article/b53a4a6c9af0401e80fdecf80f95818b
Autor:
Mara C. Ebeling, Jorge R. Polanco, Jun Qu, Chengjian Tu, Sandra R. Montezuma, Deborah A. Ferrington
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101552- (2020)
Age-related macular degeneration (AMD) is the leading cause of blindness among the elderly. Currently, there are no treatments for dry AMD, which is characterized by the death of retinal pigment epithelium (RPE) and photoreceptors. Reports from human
Externí odkaz:
https://doaj.org/article/a55855962e5c4134884dab1d13f5424a
Autor:
Deborah A. Ferrington, Mara C. Ebeling, Rebecca J. Kapphahn, Marcia R. Terluk, Cody R. Fisher, Jorge R. Polanco, Heidi Roehrich, Michaela M. Leary, Zhaohui Geng, James R. Dutton, Sandra R. Montezuma
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 255-265 (2017)
Age-related macular degeneration (AMD) is the leading cause of blindness among older adults. It has been suggested that mitochondrial defects in the retinal pigment epithelium (RPE) underlies AMD pathology. To test this idea, we developed primary cul
Externí odkaz:
https://doaj.org/article/795e7501dc7c4dc9a15e49597a81a8ba
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231212 (2020)
PLoS ONE
PLoS ONE
Two major proteolytic systems, the proteasome and the autophagy pathway, are key components of the proteostasis network. The immunoproteasome, a proteasome subtype, and autophagy are upregulated under stress conditions, forming a coordinated unit des
Autor:
Deborah A. Ferrington, Kris Genelyn Dimasuay, Hong Wei Chu, Jorge R. Polanco, Amelia Sanchez, Niccolette Schaefer
Publikováno v:
Clinical Science. 132:1711-1723
Rhinovirus (RV) infection is involved in acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD). RV primarily infects upper and lower airway epithelium. Immunoproteasomes (IP) are proteolytic machineries with multiple function
Autor:
Heidi Roehrich, Cody R. Fisher, Michaela M. Leary, Zhaohui Geng, Marcia R. Terluk, James R. Dutton, Deborah A. Ferrington, Sandra R. Montezuma, Rebecca J. Kapphahn, Jorge R. Polanco, Mara C. Ebeling
Publikováno v:
Redox Biology
Redox Biology, Vol 13, Iss C, Pp 255-265 (2017)
Redox Biology, Vol 13, Iss C, Pp 255-265 (2017)
Age-related macular degeneration (AMD) is the leading cause of blindness among older adults. It has been suggested that mitochondrial defects in the retinal pigment epithelium (RPE) underlies AMD pathology. To test this idea, we developed primary cul