Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Jorge O. Galante"'
Autor:
Jonathan M. Frank, Vincent M. Wang, John D. Sandy, Katie J. Trella, Eleni Stylianou, Jun Li, Robert W. Wysocki, Jorge O. Galante, Anna Plaas
Publikováno v:
Journal of Orthopaedic Research. 35:947-955
We have used a murine Achilles tendinopathy model to investigate whether tissue changes (such as collagen disorganization, chondroid metaplasia, and loss of tensile properties) which are broadly characteristic of human tendinopathies, are accompanied
Autor:
John D. Sandy, Elizabeth Shewman, Bernard R. Bach, Karen L. Troy, Brian J. Cole, Jun Li, Vincent M. Wang, Anna Plaas, Jorge O. Galante, Katalin Mikecz, Rebecca Bell
Publikováno v:
Journal of Orthopaedic Research. 31:1540-1548
A recently developed murine model of tendinopathy, induced by TGF-b1 injection, has been used to examine the reparative capacity of tendinopathic Achilles in Adamts5 � /� mice. After TGF-b1 injection and 2 weeks of treadmill exercise, the Achille
Autor:
Craig J. Della Valle, Richard A. Berger, Jared R.H. Foran, Nicholas M. Brown, Jorge O. Galante
Publikováno v:
Clinical Orthopaedics & Related Research. 471:102-108
In a previously reported series of 51 patients with 62 cemented, fixed-bearing unicompartmental knee arthroplasties, we reported a 10-year, 98% survival rate with an average knee score of 92 points. The survivorship and modes of failure past 10 years
Autor:
Jane Z. Liu, Nicholas B. Frisch, Craig D. Silverton, Jorge O. Galante, Regina M. Barden, Aaron G. Rosenberg
Publikováno v:
The Journal of arthroplasty. 32(4)
Background Heterotopic ossification (HO) is a known complication following total hip arthroplasty. Radiation is an effective prophylaxis, but an optimal protocol has yet to be determined. We performed a randomized, double-blinded clinical trial in hi
Autor:
John D. Sandy, Anthony A. Romeo, Vincent M. Wang, Eli T. Sayegh, Anna Plaas, Jorge O. Galante, Mandeep S. Virk, Robert W. Wysocki, Katie J. Trella
Publikováno v:
Current tissue engineering. 4(2)
There exists a range of surgical and non-surgical approaches to the treatment of both acute and chronic tendon injuries. Despite surgical advances in the management of acute tears and increasing treatment options for tendinopathies, strategies freque
Autor:
Shuguang Gao, Jorge O. Galante, Anna Plaas, Sabrina H. Brounts, Katie J. Trella, John D. Sandy, Jun Li, Daniel J. Gorski, Wei Luo
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167069 (2016)
PLoS ONE
PLoS ONE
Equine degenerative suspensory ligament desmitis (DSLD) in Peruvian Paso horses typically presents at 7-15 years and is characterized by lameness, focal disorganization of collagen fibrils, and chondroid deposition in the body of the ligament. With t
Autor:
Jorge O. Galante, Craig J. Della Valle, Markus A. Wimmer, Deborah J. Hall, Joshua J. Jacobs, Robert M. Urban
Publikováno v:
The Journal of Bone & Joint Surgery. 94:1877-1885
Background: Primary cementless acetabular reconstruction has shown durable long-term fixation. Late failures secondary to aseptic loosening are rare but may occur in patients with previously well-fixed components. In the present study, the histopatho
Publikováno v:
Clinical Orthopaedics & Related Research. 470:1814-1825
Surface damage of the tibial polyethylene insert in TKA is thought to diminish with increasing conformity, based on computed lower contact stresses. Added constraint from higher conformity may, however, result in greater forces in vivo.We therefore d
Murine tendon function is adversely affected by aggrecan accumulation due to the knockout of ADAMTS5
Autor:
David R. Eyre, Rebecca Bell, Ruchir Thakore, Jorge O. Galante, Vincent M. Wang, Anna Plaas, Jun Li, John D. Sandy
Publikováno v:
Journal of Orthopaedic Research. 30:620-626
The present study examined the effect of ADAMTS5 (TS5) knockout on the properties of murine flexor digitorum longus (FDL) and Achilles tendons. FDL and Achilles tendons were analyzed using biomechanical testing, histology, and immunohistochemistry; f