Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jorge Merlet"'
Publikováno v:
MethodsX, Vol 11, Iss , Pp 102293- (2023)
Caenorhabditis elegans is a model system widely used in fundamental research. Even though, nematodes are easy to maintain in the laboratory, obtaining large populations of worms require a lot of work and is time consuming. Furthermore, because C. ele
Externí odkaz:
https://doaj.org/article/fa84683c9425443fa3de4f93d4d3cd00
Publikováno v:
iScience, Vol 24, Iss 1, Pp 102029- (2021)
Summary: Loss of membrane potential of sperm mitochondria has been regarded as the first step preceding mitophagy degradation after their entry into the C. elegans oocyte at fertilization. This is in line with the classical view of mitophagy of defec
Externí odkaz:
https://doaj.org/article/9576d330e8c04637b42351cf4acf9b58
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 10, Pp 3431-3442 (2016)
Cullin-RING E3-Ligases (CRLs), the largest family of E3 ubiquitin-Ligases, regulate diverse cellular processes by promoting ubiquitination of target proteins. The evolutionarily conserved Leucine Rich Repeat protein 1 (LRR-1) is a substrate-recogniti
Externí odkaz:
https://doaj.org/article/4b84a52a943f4da1a436998274c9a4f9
Autor:
Silvia Gutnik, Yann Thomas, Yanwu Guo, Janosch Stoecklin, Anca Neagu, Lionel Pintard, Jorge Merlet, Rafal Ciosk
Publikováno v:
Biology Open, Vol 7, Iss 7 (2018)
The Notch signalling pathway is a conserved and widespread signalling paradigm, and its misregulation has been implicated in numerous disorders, including cancer. The output of Notch signalling depends on the nuclear accumulation of the Notch recepto
Externí odkaz:
https://doaj.org/article/a97deb6571094184b91de9c9b335e6e2
Autor:
Valérie J. Robert, Marine G. Mercier, Cécile Bedet, Stéphane Janczarski, Jorge Merlet, Steve Garvis, Rafal Ciosk, Francesca Palladino
Publikováno v:
Cell Reports, Vol 9, Iss 2, Pp 443-450 (2014)
Histone H3 Lys 4 methylation (H3K4me) is deposited by the conserved SET1/MLL methyltransferases acting in multiprotein complexes, including Ash2 and Wdr5. Although individual subunits contribute to complex activity, how they influence gene expression
Externí odkaz:
https://doaj.org/article/7b0845342d244d3b8c4f4273e09a107d
Autor:
Julien Burger, Jorge Merlet, Nicolas Tavernier, Bénédicte Richaudeau, Andreas Arnold, Rafal Ciosk, Bruce Bowerman, Lionel Pintard
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003375 (2013)
The ubiquitin-proteolytic system controls the stability of proteins in space and time. In this study, using a temperature-sensitive mutant allele of the cul-2 gene, we show that CRL2(LRR-1) (CUL-2 RING E3 ubiquitin-ligase and the Leucine Rich Repeat
Externí odkaz:
https://doaj.org/article/79cbc2099e0f404d888adb3b5d25e4fd
Autor:
Stéphanie Migrenne, Evelyne Moreau, Pirjo Pakarinen, Andrée Dierich, Jorge Merlet, René Habert, Chrystèle Racine
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53257 (2012)
It is currently admitted that Follicle-Stimulating Hormone (FSH) is physiologically involved in the development and function of fetal/neonatal Sertoli cells in the rat but not the mouse. However, FSH is produced by both species from late fetal life o
Externí odkaz:
https://doaj.org/article/ad20107a1fcf45a89e911906bbfa1028
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 10, Pp 3431-3442 (2016)
G3
G3, Genetics Society of America, 2016, 6 (10), pp.3431-3442. ⟨10.1534/g3.116.033043⟩
G3, 2016, 6 (10), pp.3431-3442. ⟨10.1534/g3.116.033043⟩
G3: Genes|Genomes|Genetics
G3
G3, Genetics Society of America, 2016, 6 (10), pp.3431-3442. ⟨10.1534/g3.116.033043⟩
G3, 2016, 6 (10), pp.3431-3442. ⟨10.1534/g3.116.033043⟩
G3: Genes|Genomes|Genetics
Cullin-RING E3-Ligases (CRLs), the largest family of E3 ubiquitin-Ligases, regulate diverse cellular processes by promoting ubiquitination of target proteins. The evolutionarily conserved Leucine Rich Repeat protein 1 (LRR-1) is a substrate-recogniti
Publikováno v:
Advances in anatomy, embryology, and cell biology. 231
The nematode C. elegans represents a powerful experimental system with key properties and advantages to study the mechanisms underlying mitochondrial DNA maternal inheritance and paternal components sorting. First, the transmission is uniparental and
Publikováno v:
Cellular and Molecular Basis of Mitochondrial Inheritance ISBN: 9783030045692
Cellular and Molecular Basis of Mitochondrial Inheritance
Cellular and Molecular Basis of Mitochondrial Inheritance, pp.1-23, 2019, ⟨10.1007/102_2018_1⟩
Cellular and Molecular Basis of Mitochondrial Inheritance
Cellular and Molecular Basis of Mitochondrial Inheritance, pp.1-23, 2019, ⟨10.1007/102_2018_1⟩
The nematode C. elegans represents a powerful experimental system with key properties and advantages to study the mechanisms underlying mitochondrial DNA maternal inheritance and paternal components sorting. First, the transmission is uniparental and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e002107f02ea4bff3095c86bd5effe68
https://doi.org/10.1007/102_2018_1
https://doi.org/10.1007/102_2018_1