Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jorge Martínez-Cano"'
Autor:
Marta Isidro-Hernández, Ana Casado-García, Ninad Oak, Silvia Alemán-Arteaga, Belén Ruiz-Corzo, Jorge Martínez-Cano, Andrea Mayado, Elena G. Sánchez, Oscar Blanco, Ma Luisa Gaspar, Alberto Orfao, Diego Alonso-López, Javier De Las Rivas, Susana Riesco, Pablo Prieto-Matos, África González-Murillo, Francisco Javier García Criado, María Begoña García Cenador, Manuel Ramírez-Orellana, Belén de Andrés, Carolina Vicente-Dueñas, César Cobaleda, Kim E. Nichols, Isidro Sánchez-García
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The initial steps of B-cell acute lymphoblastic leukemia (B-ALL) development usually pass unnoticed in children. Several preclinical studies have shown that exposure to immune stressors triggers the transformation of preleukemic B cells to f
Externí odkaz:
https://doaj.org/article/7edbe4149620489b8ca43749dc557848
Autor:
Marta Isidro-Hernández, Silvia Alemán-Arteaga, Ana Casado-García, Belén Ruiz-Corzo, Susana Riesco, Pablo Prieto-Matos, Jorge Martínez-Cano, Lucía Sánchez, César Cobaleda, Isidro Sánchez-García, Carolina Vicente-Dueñas
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7562 (2022)
Leukemia is the most usual childhood cancer, and B-cell acute lymphoblastic leukemia (B-ALL) is its most common presentation. It has been proposed that pediatric leukemogenesis occurs through a “multi-step” or “multi-hit” mechanism that inclu
Externí odkaz:
https://doaj.org/article/6fcb55c894724879b3e36d4814338e87
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Immunodeficiencies (IDs) are disorders of the immune system that increase susceptibility to infections and cancer, and are therefore associated with elevated morbidity and mortality. IDs can be primary (not caused by other condition or exposure) or s
Externí odkaz:
https://doaj.org/article/2748fa40c72949afa15cc846ab14adcd
Autor:
Isidro Sánchez-García, Kim E. Nichols, Andreas Weiss, Carolina Vicente-Dueñas, Jun J. Yang, César Cobaleda, Manuel Ramírez-Orellana, Thomas Radimerski, María Begoña García Cenador, Francisco Javier García Criado, África González-Murillo, Pablo Prieto-Matos, Susana Riesco, Javier De Las Rivas, Diego Alonso-López, Alberto Orfao, Oscar Blanco, Jorge Martínez-Cano, Elena G. Sánchez, Dario Sterker, Alexandra Buhles, Silvia Alemán-Arteaga, Javier Raboso-Gallego, Christine Mann-Ran, Andrea Mayado, Ninad Oak, Marta Isidro-Hernández, Ana Casado-García
Supplementary Data from Transient Inhibition of the JAK/STAT Pathway Prevents B-ALL Development in Genetically Predisposed Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727afcdf4ae3e49d8ce4cc51b3aadc6f
https://doi.org/10.1158/0008-5472.22431237.v1
https://doi.org/10.1158/0008-5472.22431237.v1
Autor:
Ana Casado-García, Marta Isidro-Hernández, Ninad Oak, Andrea Mayado, Christine Mann-Ran, Javier Raboso-Gallego, Silvia Alemán-Arteaga, Alexandra Buhles, Dario Sterker, Elena G. Sánchez, Jorge Martínez-Cano, Oscar Blanco, Alberto Orfao, Diego Alonso-López, Javier De Las Rivas, Susana Riesco, Pablo Prieto-Matos, África González-Murillo, Francisco Javier García Criado, María Begoña García Cenador, Thomas Radimerski, Manuel Ramírez-Orellana, César Cobaleda, Jun J. Yang, Carolina Vicente-Dueñas, Andreas Weiss, Kim E. Nichols, Isidro Sánchez-García
Publikováno v:
Cancer Research. 82:1098-1109
Preventing development of childhood B-cell acute lymphoblastic leukemia (B-ALL), a disease with devastating effects, is a longstanding and unsolved challenge. Heterozygous germline alterations in the PAX5 gene can lead to B-ALL upon accumulation of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b72de6fa5ba3d728c6fd3434d4803f
https://doi.org/10.1158/0008-5472.can-21-3386
https://doi.org/10.1158/0008-5472.can-21-3386
Autor:
Lucía del Pino Molina, Eduardo López-Granados, Elena Campos-Sanchez, Jorge Martínez-Cano, César Cobaleda
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Primary immunodeficiencies (PIDs) are immune disorders resulting from defects in genes involved in immune regulation, and manifesting as an increased susceptibility to infections, autoimmunity, and cancer. However, the molecular basis of some prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af1b84fdfc0979f5f43c5c62e0fc01b
http://hdl.handle.net/10261/214519
http://hdl.handle.net/10261/214519