Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jorge Lazaro"'
Publikováno v:
PLoS Biology, Vol 19, Iss 11, p e3001450 (2021)
The molecular mechanisms that produce the full array of neuronal subtypes in the vertebrate nervous system are incompletely understood. Here, we provide evidence of a global temporal patterning program comprising sets of transcription factors that st
Externí odkaz:
https://doaj.org/article/1f4bade4a91e47e8a61775cad7bde81e
Autor:
Jeremy Dufourt, Antonio Trullo, Jennifer Hunter, Carola Fernandez, Jorge Lazaro, Matthieu Dejean, Lucas Morales, Saida Nait-Amer, Katharine N. Schulz, Melissa M. Harrison, Cyril Favard, Ovidiu Radulescu, Mounia Lagha
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Zelda is a pioneer factor that regulates transcription in Drosophila embryos. Here, the authors use quantitative live imaging and mathematical modeling to measure the effect of Zelda on transcriptional dynamics and memory, observing temporal control
Externí odkaz:
https://doaj.org/article/6f73d116eb0e46649c4a65fbc2648168
Autor:
Jeremy Dufourt, Antonio Trullo, Jennifer Hunter, Carola Fernandez, Jorge Lazaro, Matthieu Dejean, Lucas Morales, Saida Nait-Amer, Katharine N. Schulz, Melissa M. Harrison, Cyril Favard, Ovidiu Radulescu, Mounia Lagha
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in Fig. 4a, in which the “=” sign of the equation was inadvertently replaced with a “-“ sign. This has been corrected in the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/3852cdc6f5bd434b89b45585c692d978
Autor:
Clayton J. Harry, Jonathan D. Hibshman, Amor Damatac, II, Phillip L. Davidson, Martin Andres Estermann, Marycruz Flores-Flores, Caroline M. Holmes, Jorge Lázaro, Elizabeth-Ann Legere, Jake Leyhr, Siddharthan Balachandar Thendral, Bridget A. Vincent, Bob Goldstein
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103232- (2024)
Summary: Tardigrades are microscopic organisms with exceptional resilience to environmental extremes. Most protocols to visualize the internal anatomy of tardigrades rely on fixation, hampering our understanding of dynamic changes to organelles and o
Externí odkaz:
https://doaj.org/article/e74dabf59a4e4972a4db68e6cff106fd
The molecular mechanisms that ensure the reproducible generation of neuronal diversity in the vertebrate nervous system are incompletely understood. Here we provide evidence of a temporal patterning program consisting of cohorts of transcription fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f3620c2f935bed8b2f719f01a6eac80
https://doi.org/10.1101/2020.11.10.376491
https://doi.org/10.1101/2020.11.10.376491
Autor:
Jorge Lazaro, Christopher Barrington, Lorena Garcia-Perez, Victor L. J. Tybulewicz, Despina Stamataki, James Briscoe, Elizabeth M. C. Fisher, Ruben Perez-Carrasco, Manuela Melchionda, Teresa Rayon, Katherine Exelby
Publikováno v:
Science
Setting the tempo for development Many animals display similarities in their organization (body axis, organ systems, and so on). However, they can display vastly different life spans and thus must accommodate different developmental time scales. Two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d1bf4c3bc73a489b910e3cfc382a8e
https://doi.org/10.1126/science.aba7667
https://doi.org/10.1126/science.aba7667
Publikováno v:
PLoS Biology, Vol 19, Iss 11, p e3001450 (2021)
PLoS Biology
PLoS Biology
The molecular mechanisms that produce the full array of neuronal subtypes in the vertebrate nervous system are incompletely understood. Here, we provide evidence of a global temporal patterning program comprising sets of transcription factors that st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65762e90e22b17c4395b360692f0a9c4
https://doi.org/10.1371/journal.pbio.3001450
https://doi.org/10.1371/journal.pbio.3001450
Autor:
Katharine N. Schulz, Cyril Favard, Carola Fernandez, Matthieu Dejean, Mounia Lagha, Jeremy Dufourt, Jorge Lazaro, Jennifer Hunter, Melissa M. Harrison, Ovidiu Radulescu, Saida Nait-Amer, Antonio Trullo, Lucas Morales
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Pioneer transcription factors can engage nucleosomal DNA, which leads to local chromatin remodeling and to the establishment of transcriptional competence. However, the impact of enhancer priming by pioneer factors on the temporal control of gene exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b9db2ef7c4f5edcb53329ebe5228ae
http://europepmc.org/articles/PMC6333798
http://europepmc.org/articles/PMC6333798
Autor:
Alejandro G. García-Ruiz de Morales, María Jesús Vivancos, Jorge Lázaro, Beatriz Romero Hernández, Beatriz Mateos, Pilar Pérez-Elías, Margarita Herrero Delgado, Laura Villanova Cuadra, Santiago Moreno, Javier Martínez-Sanz, María Jesús Pérez-Elías
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1846 (2024)
Despite remarkable improvement in the human immunodeficiency virus (HIV) and hepatitis C virus (HCV) care continuum, the rate of late diagnosis of HIV and HCV in high-income countries remains unacceptably high. Testing relies mainly on primary care p
Externí odkaz:
https://doaj.org/article/bd96d538550841f99b0ad787b3d3de48
Autor:
Jeremy Dufourt, Jennifer Hunter, Saida Nait-Amer, Jorge Lazaro, Matthieu Dejean, Cyril Favard, Melissa Harrison, Carola Fernandez, Mounia Lagha, Antonio Trullo, Lucas Morales, Katharine N. Schulz, Ovidiu Radulescu
/introPioneer factors have the exquisite ability to engage their target sites at nucleosomal DNA, which leads to a local remodeling of chromatin and the establishment of a transcriptional competence. However, the direct impact of enhancer priming by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f035bd710dc3912da483db5f3e92f03