Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jorge Ivan Alvarez"'
Autor:
Mathias Linnerbauer, Tobias Beyer, Lucy Nirschl, Daniel Farrenkopf, Lena Lößlein, Oliver Vandrey, Anne Peter, Thanos Tsaktanis, Hania Kebir, David Laplaud, Rupert Oellinger, Thomas Engleitner, Jorge Ivan Alvarez, Roland Rad, Thomas Korn, Bernhard Hemmer, Francisco J. Quintana, Veit Rothhammer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Multiple Sclerosis (MS) is a chronic autoimmune inflammatory disorder of the central nervous system (CNS). Current therapies mainly target inflammatory processes during acute stages, but effective treatments for progressive MS are limited. I
Externí odkaz:
https://doaj.org/article/5f7fdf63aa804452bff90537ad8c51b1
Autor:
Cen Li, Cuiying Niu, Hongtao Bi, Jing Zhao, Jorge Ivan Alvarez, Farong Yuan, Xiangyun Gai, Lixin Wei, Yuzhi Du, Yajun Qiao, Hania Kebir, Yuancan Xiao, Hongxia Yang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction:Zuotai is an ancient mineral-herbal mixture containing β-HgS in Tibetan medicine. It is used to treat nervous system diseases, similar to Chinese medicine cinnabar and Indian Ayurveda medicine Rasasindura. However, one of the key proble
Externí odkaz:
https://doaj.org/article/e2e7abfbbd234fc886a6466aa2f7ccfb
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/03251509df2e438d8bc1e423e28087cd
Autor:
Fred Lühder, Hania Kebir, Francesca Odoardi, Tanja Litke, Maike Sonneck, Jorge Ivan Alvarez, Jan Winchenbach, Nadine Eckert, Liat Hayardeny, Ella Sorani, Dmitri Lodygin, Alexander Flügel, Alexandre Prat
Publikováno v:
Neurobiology of Disease, Vol 102, Iss , Pp 60-69 (2017)
Laquinimod is currently being tested as a therapeutic drug in multiple sclerosis. However, its exact mechanism of action is still under investigation. Tracking of fluorescently-tagged encephalitogenic T cells during experimental autoimmune encephalom
Externí odkaz:
https://doaj.org/article/bb0d65d19072434a88849b414fc214b3
Autor:
Jorge Ivan Alvarez, Olivia Saint-Laurent, Alisha Godschalk, Simone Terouz, Casper Briels, Sandra Larouche, Lyne Bourbonnière, Catherine Larochelle, Alexandre Prat
Publikováno v:
Neurobiology of Disease, Vol 74, Iss , Pp 14-24 (2015)
Early changes in the normal appearing white matter of multiple sclerosis (MS) patients precede the appearance of gadolinium-enhancing lesions. Although these findings suggest blood–brain barrier (BBB) breakdown as an important feature in MS pathoge
Externí odkaz:
https://doaj.org/article/9727d0fd5e3b4d4b92a9a292fdfccc6e
Autor:
Antoine Philippe Fournier, Stephanie Zandee, Marc Charabati, Evelyn Peelen, Olivier Tastet, Jorge Ivan Alvarez, Hania Kebir, Lyne Bourbonnière, Sandra Larouche, Boaz Lahav, Wendy Klement, Fiona Tea, Alain Bouthillier, Robert Moumdjian, Romain Cayrol, Pierre Duquette, Marc Girard, Catherine Larochelle, Nathalie Arbour, Alexandre Prat
Publikováno v:
Neurology(R) neuroimmunologyneuroinflammation. 9(6)
Background and ObjectivesIn multiple sclerosis (MS), peripheral immune cells use various cell trafficking molecules to infiltrate the CNS where they cause damage.The objective of this study was to investigate the involvement of coxsackie and adenovir
Autor:
Alexis Mary Crockett, Nail Benallegue, Philippa Adelman, Raquel Gur, Kathleen E Sullivan, Stewart A Anderson, Jorge Ivan Alvarez
Publikováno v:
The Journal of Immunology. 206:52.11-52.11
Mice modeling the hemizygous deletion of chromosome 22q11.2 (22qMc) have been utilized to address various clinical phenotypes associated with the disease, including cardiac malformations, altered neural circuitry and behavioral deficits. Yet, the sta
Autor:
Giacomo Casella, Javad Rasouli, Rodolfo Thome, Jorge Ivan Alvarez, Christopher A Hunter, Guang-Xian Zhang, Bogoljub Ciric, Abdolmohamad M Rostami
Publikováno v:
The Journal of Immunology. 204:78.15-78.15
The induction of peripheral tolerance by intravenous injection (i.v.) of auto-Ags has shown to suppress experimental autoimmune encephalomyelitis (EAE), a mouse model of Multiple Sclerosis, by eliciting tolerogenic APCs, Tregs, and suppressing self-r
Autor:
Catherine, Larochelle, Marc-André, Lécuyer, Jorge Ivan, Alvarez, Marc, Charabati, Olivia, Saint-Laurent, Soufiane, Ghannam, Hania, Kebir, Ken, Flanagan, Ted, Yednock, Pierre, Duquette, Nathalie, Arbour, Alexandre, Prat
Publikováno v:
Annals of neurology. 78(1)
Although Tc17 lymphocytes are enriched in the central nervous system (CNS) of multiple sclerosis (MS) subjects and of experimental autoimmune encephalomyelitis (EAE) animals, limited information is available about their recruitment into the CNS and t
Publikováno v:
Escritos, Vol 21, Iss 46 (2020)
Después de la publicación de su tesis doctoral titulada La acción (1893), el filósofo francés Maurice Blondel escribió algunas obras en las que trató asuntos de enorme importancia, tanto en el campo filosófico como teológico, que desarrollar
Externí odkaz:
https://doaj.org/article/8e44cefadeda4671b8ac9ab511f1721f