Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Jorge H. Medina"'
Autor:
Juliana F. Dalto, Jorge H. Medina
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The fate of memories depends mainly on two opposing forces: the mechanisms required for the storage and maintenance of memory and the mechanisms underlying forgetting, being the latter much less understood. Here, we show the effect of inhibi
Externí odkaz:
https://doaj.org/article/ce24593ac2554e7685cd3d0c8bc7ca91
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
The retrosplenial cortex (RSC) has been widely related to spatial and contextual memory. However, we recently demonstrated that the anterior part of the RSC (aRSC) is required for object recognition (OR) memory consolidation. In this study, we aimed
Externí odkaz:
https://doaj.org/article/f15b6c0df3a3441b83bd256b17d8910e
Autor:
Pedro Benedetti, Alejo Barbuzza, Franco Moscato, Victoria Reppucci, Celina Goyeneche, Cynthia Katche, Jorge H. Medina, Haydee Viola, Fabricio Ballarini, Diego Moncada
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
BackgroundSince the irruption of the coronavirus disease 2019 (COVID-19) the planet has submerged in a time of concern and uncertainty, with a direct impact on people's mental health. Moreover, the recurrent outbreaks that periodically harry differen
Externí odkaz:
https://doaj.org/article/44da52e91a454938a50444f7ab025951
Autor:
Magdalena Pereyra, Jorge H. Medina
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
Retrieval constitutes a highly regulated and dynamic phase in memory processing. Its rapid temporal scales require a coordinated molecular chain of events at the synaptic level that support transient memory trace reactivation. AMPA receptors (AMPAR)
Externí odkaz:
https://doaj.org/article/a9c25b88fe04406499948c9508a9def9
Autor:
Jorge H. Medina, Haydee Viola
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Extracellular regulated kinase 1/2 (ERK1/2) has been strongly implicated in several cellular processes. In the brain ERK1/2 activity has been primarily involved in long-term memory (LTM) formation and expression. Here, we review earlier evidence and
Externí odkaz:
https://doaj.org/article/7903a158ae0242c0941c2536beb5b356
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Many psychiatric disorders, despite their specific characteristics, share deficits in the cognitive domain including executive functions, emotional control and memory. However, memory deficits have been in many cases undervalued compared with other c
Externí odkaz:
https://doaj.org/article/f48b2f34fb5c435bb09f7933c3ebbc8f
Autor:
Jorge H. Medina
Publikováno v:
Frontiers in Systems Neuroscience, Vol 12 (2018)
The neurobiology of memory formation attracts much attention in the last five decades. Conversely, the rules that govern and the mechanisms underlying forgetting are less understood. In addition to retroactive interference, retrieval-induced forgetti
Externí odkaz:
https://doaj.org/article/d051b47d8f194b309263528f02e4cc7c
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 11 (2017)
It is well established that neurons of the mammalian medial prefrontal cortex (mPFC) modulate different behavioral outputs, including several memory types. This behavioral modulation is, at least in part, under the control of the D1-like Dopamine (DA
Externí odkaz:
https://doaj.org/article/fa5330c328a346ac9f38dd0d75cb9814
Autor:
Iván Izquierdo, Martín Cammarota, Weber C. Da Silva, Lia R.M. Bevilaqua, Janine I. Rossato, Juliana S. Bonini, Pamela Mello, Fernando Benetti, Jaderson C. Costa, Jorge H. Medina
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 80, Iss 1, Pp 115-127 (2008)
Long-term potentiation (LTP) is the enhancement of postsynaptic responses for hours, days or weeks following the brief repetitive afferent stimulation of presynaptic afferents. It has been proposed many times over the last 30 years to be the basis of
Externí odkaz:
https://doaj.org/article/86f84e1db09d45348fca9c6b02ec5fdc
Publikováno v:
Neural Plasticity, Vol 2015 (2015)
The synaptic tagging and capture (STC) hypothesis provides a compelling explanation for synaptic specificity and facilitation of long-term potentiation. Its implication on long-term memory (LTM) formation led to postulate the behavioral tagging mecha
Externí odkaz:
https://doaj.org/article/b23dd5668ddd46009804edb52a6fdba9