Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Jorge H. Capdevila"'
Autor:
Jorge H. Capdevila, John R. Falck
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2047-2062 (2018)
The initial studies of the metabolism of arachidonic acid (AA) by the cytochrome P450 (P450) hemeproteins sought to: a) elucidate the roles for these enzymes in the metabolism of endogenous pools of the FA, b) identify the P450 isoforms involved in A
Externí odkaz:
https://doaj.org/article/067194c7a90b4c78984e3ec2e7a83202
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 2, Pp 163-181 (2000)
The demonstration of in vivo arachidonic acid epoxidation and ω-hydroxylation established the cytochrome P450 epoxygenase and ω/ω–1 hydroxylase as formal metabolic pathways and as members of the arachidonate metabolic cascade. The characterizati
Externí odkaz:
https://doaj.org/article/0cb04ae36ca0456bae5bd9e269a804c9
Autor:
Ambra Pozzi, Jorge H. Capdevila
Publikováno v:
PPAR Research, Vol 2008 (2008)
Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear receptor family of ligand-activated transcription factors. This subfamily is composed of three members—PPARα, PPARδ, and PPARγ—that differ in their cell and tissue distr
Externí odkaz:
https://doaj.org/article/3afcfdadcc5743dd85c2ef904e44df0a
Autor:
Ambra Pozzi, Scott M. Williams, F. Peter Guengerich, John R. Falck, Jorge H. Capdevila, Megan M. Shuey, James M. Luther, Roy Zent, Shouzuo Wei, Shaojun Mei, Manuel Chiusa, Mahesha H. Gangadhariah, Lindsay N. Sausville
This file contains the primer sequence of CYP2C9* variants (Supplementary Table S1); the SNPs genotyped in the BioVU NSCLC study (Supplementary Table S2); quality control measures of SNPs in the BioVU NSCLC study (Supplementary Table S3); clinical an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308f7412116c1324a40a6f5c93f46538
https://doi.org/10.1158/0008-5472.22426270.v1
https://doi.org/10.1158/0008-5472.22426270.v1
Autor:
Ambra Pozzi, Scott M. Williams, F. Peter Guengerich, John R. Falck, Jorge H. Capdevila, Megan M. Shuey, James M. Luther, Roy Zent, Shouzuo Wei, Shaojun Mei, Manuel Chiusa, Mahesha H. Gangadhariah, Lindsay N. Sausville
Increased expression of cytochrome P450 CYP2C9, together with elevated levels of its products epoxyeicosatrienoic acids (EET), is associated with aggressiveness in cancer. Cytochrome P450 variants CYP2C9*2 and CYP2C9*3 encode proteins with reduced en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff77c3335eea0c969f51ecdd1f48097
https://doi.org/10.1158/0008-5472.c.6512281
https://doi.org/10.1158/0008-5472.c.6512281
Autor:
Ambra Pozzi, Jorge H. Capdevila, Roy Zent, Jawahar Lal Jat, John R. Falck, Shouzuo Wei, Mahesha Gangadhariah, Shilin Yang, Stacey Mont, Yan Su, Wen Hu, Xiwu Chen, Nataliya Skrypnyk
PDF file - 68K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f303a30d8a413425d64342157b34c2f
https://doi.org/10.1158/0008-5472.22402593.v1
https://doi.org/10.1158/0008-5472.22402593.v1
Autor:
Ambra Pozzi, Jorge H. Capdevila, Roy Zent, Jawahar Lal Jat, John R. Falck, Shouzuo Wei, Mahesha Gangadhariah, Shilin Yang, Stacey Mont, Yan Su, Wen Hu, Xiwu Chen, Nataliya Skrypnyk
PDF file - 24K, Analysis of p60.5 and KrasLA2 tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486024e2d3eeddba2b9278b139130444
https://doi.org/10.1158/0008-5472.22402602.v1
https://doi.org/10.1158/0008-5472.22402602.v1
Autor:
Ambra Pozzi, Jorge H. Capdevila, Roy Zent, Jawahar Lal Jat, John R. Falck, Shouzuo Wei, Mahesha Gangadhariah, Shilin Yang, Stacey Mont, Yan Su, Wen Hu, Xiwu Chen, Nataliya Skrypnyk
PDF file - 99K, Analysis of human GFP-A549 NSCLC tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc05fa949ddeeeafa2a2ad9e8a06f42
https://doi.org/10.1158/0008-5472.22402599.v1
https://doi.org/10.1158/0008-5472.22402599.v1
Autor:
Ambra Pozzi, Jorge H. Capdevila, Roy Zent, Jawahar Lal Jat, John R. Falck, Shouzuo Wei, Mahesha Gangadhariah, Shilin Yang, Stacey Mont, Yan Su, Wen Hu, Xiwu Chen, Nataliya Skrypnyk
PDF file - 40K, Treatment of athymic mice orthotopically injected with human GFP-A549 cells with Bezafibrate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358bb3c570cc69d8ff47939b7b9cd367
https://doi.org/10.1158/0008-5472.22402596
https://doi.org/10.1158/0008-5472.22402596
Autor:
John D Imig, Ahmed eElmarakby, Kasem eNithipatikom, Shouzou eWei, Jorge H Capdevila, Venugopal R Tuniki, Bhavani eSangras, Siddam eAnjaiah, Vijaya L Manthati, D. Sudarashan Reddy, John R Falck
Publikováno v:
Frontiers in Physiology, Vol 1 (2010)
Epoxyeicosatrienoic acids (EETs) contribute importantly to the regulation of vascular tone and blood pressure control. The purpose of this study was to develop stable EET analogs and test their in vivo blood pressure lowering effects in hypertensive
Externí odkaz:
https://doaj.org/article/b3ad7da4ab0b4927ae4676009e3a8107