Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jorge González-Bacerio"'
Autor:
Héctor Nolasco-Soria, Carlos Alfonso Alvarez-González, Dariel Tovar-Ramírez, Jorge González-Bacerio, Alberto del Monte-Martínez, Fernando Vega-Villasante
Publikováno v:
Fishes, Vol 9, Iss 7, p 261 (2024)
Fish possess lipases from embryonic development to adulthood. Lipase activity methods vary and significantly differ in terms of the concentration of the substrate used, bile salt, Ca2+, temperature, pH, and type of lipase units, which limits comparat
Externí odkaz:
https://doaj.org/article/2d9399f1f1754782a34fb4b980ad8103
Autor:
Maikel Izquierdo, De Lin, Sandra O'Neill, Lauren A Webster, Christy Paterson, John Thomas, Mirtha Elisa Aguado, Enrique Colina Araújo, Daniel Alpízar-Pedraza, Halimatu Joji, Lorna MacLean, Anthony Hope, David W Gray, Martin Zoltner, Mark C Field, Jorge González-Bacerio, Manu De Rycker
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011956 (2024)
BackgroundChagas disease is caused by the protozoan parasite Trypanosoma cruzi and leads to ~10,000 deaths each year. Nifurtimox and benznidazole are the only two drugs available but have significant adverse effects and limited efficacy. New chemothe
Externí odkaz:
https://doaj.org/article/eda16b548238447697b8e6f336b5e1ca
Autor:
Jorge González-Bacerio, Maikel Izquierdo, Mirtha Elisa Aguado, Ana C. Varela, Maikel González-Matos, Maday Alonso del Rivero
Publikováno v:
Microbial Cell, Vol 8, Iss 10, Pp 239-246 (2021)
Several microbial metalo-aminopeptidases are emerging as novel targets for the treatment of human infectious diseases. Some of them are well validated as targets and some are not; some are essential enzymes and others are important for virulence and
Externí odkaz:
https://doaj.org/article/6d46b80827814f7c83550a392acbfd4b
Autor:
Deborah González Abradelo, Bessy V. Cutiño Ávila, Darío González Abradelo, José M. Guisán Seijas, Jorge González-Bacerio, Alberto del Monte-Martínez
Publikováno v:
Anales de la Academia de Ciencias de Cuba, Vol 12, Iss 1 (2022)
Introducción. La inmovilización de proteínas es una de las tecnologías más utilizadas para incrementar la estabilidad operacional de las enzimas y potenciar su uso en aplicaciones biotecnológicas. Usualmente, la síntesis de derivados inmoviliz
Externí odkaz:
https://doaj.org/article/70bffb561cea4848a5cc4cac2b1fe205
Autor:
Carolina C. Hoff, Mauro F. Azevedo, Adriana B. Thurler, Sarah El Chamy Maluf, Pollyana M. S. Melo, Maday Alonso del Rivero, Jorge González-Bacerio, Adriana K. Carmona, Alexandre Budu, Marcos L. Gazarini
Publikováno v:
Pathogens, Vol 10, Iss 11, p 1452 (2021)
Plasmodium falciparum, the most virulent of the human malaria parasite, is responsible for high mortality rates worldwide. We studied the M1 alanyl-aminopeptidase of this protozoan (PfA-M1), which is involved in the final stages of hemoglobin cleavag
Externí odkaz:
https://doaj.org/article/a0d20a6310e044c2a2d8837dadf331db
Autor:
Jorge González-Bacerio, Irina Arocha, Mirtha Elisa Aguado, Yanira Méndez, Sabrina Marsiccobetre, Maikel Izquierdo, Daniel G. Rivera, Katherine Figarella, Néstor L. Uzcátegui
Publikováno v:
Life, Vol 11, Iss 10, p 1037 (2021)
Chagas disease, caused by the kinetoplastid parasite Trypanosoma cruzi, is a human tropical illness mainly present in Latin America. The therapies available against this disease are far from ideal. Proteases from pathogenic protozoan have been consid
Externí odkaz:
https://doaj.org/article/76ac9f2e5b3e4002a1b154edd177f810
Autor:
Alberto del Monte-Martínez, Jorge González-Bacerio, Bessy Cutiño-Avila, Ritsie Ruiz, Rizette Avila, Miguel Ramos-Leal, Héctor Nolasco, Joaquín Díaz, José M. Guisán
Publikováno v:
Biotecnología Aplicada, Vol 32, Iss 3, Pp 3201-3210 (2015)
Externí odkaz:
https://doaj.org/article/848e3ddee2bb40d58171eba59562930a
Publikováno v:
Revista Colombiana de Biotecnología, Vol 12, Iss 1, Pp 124-140 (2010)
Las lipasas son enzimas con propiedades funcionales muy interesantes que permiten su utilización práctica en diversos campos de las industrias agroquímica, farmacéutica, de detergentes y alimentaria, así como en química fina. Entre las aplicaci
Externí odkaz:
https://doaj.org/article/aeee786140c74d199ce365dbec330c2b
Autor:
Jorge González-Bacerio, Mirtha Elisa Aguado, Maikel Izquierdo, Maikel González-Matos, Ana C. Varela, Yanira Méndez, Maday Alonso del Rivero, Daniel G. Rivera
Publikováno v:
Current Drug Targets. 24:416-461
Background: Parasitic human infectious diseases are a worldwide health problem due to the increased resistance to conventional drugs. For this reason, the identification of novel molecular targets and the discovery of new chemotherapeutic agents are
Autor:
Maikel González-Matos, Ana C. Varela, Maday Alonso del Rivero, Mirtha Elisa Aguado, Jorge González-Bacerio, Maikel Izquierdo
Publikováno v:
Microbial Cell
Microbial Cell, Vol 8, Iss 10, Pp 239-246 (2021)
Microbial Cell, Vol 8, Iss 10, Pp 239-246 (2021)
Several microbial metalo-aminopeptidases are emerging as novel targets for the treatment of human infectious diseases. Some of them are well validated as targets and some are not; some are essential enzymes and others are important for virulence and