Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Jorge G. Farías"'
Autor:
Jorge F. Beltrán, Lisandra Herrera-Belén, Fernanda Parraguez-Contreras, Jorge G. Farías, Jorge Machuca-Sepúlveda, Stefania Short
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Protein toxins are defense mechanisms and adaptations found in various organisms and microorganisms, and their use in scientific research as therapeutic candidates is gaining relevance due to their effectiveness and specificity against cellu
Externí odkaz:
https://doaj.org/article/73831bf6abb34622902c99ae43211950
Autor:
Stefania E. Short, Mauricio Zamorano, Cristian Aranzaez-Ríos, Manuel Lee-Estevez, Rommy Díaz, John Quiñones, Patricio Ulloa-Rodríguez, Elías Figueroa Villalobos, León A. Bravo, Steffen P. Graether, Jorge G. Farías
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 174 (2024)
Antifreeze proteins (AFPs) are natural biomolecules found in cold-adapted organisms that lower the freezing point of water, allowing survival in icy conditions. These proteins have the potential to improve cryopreservation techniques by enhancing the
Externí odkaz:
https://doaj.org/article/444a25a66448406caa09564aad432438
Autor:
Alejandro Pedroso, Lisandra Herrera Belén, Jorge F. Beltrán, Rodrigo L. Castillo, Adalberto Pessoa, Enrique Pedroso, Jorge G. Farías
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7550 (2023)
Acute lymphoblastic leukemia (ALL) is the most common cancer among children worldwide, characterized by an overproduction of undifferentiated lymphoblasts in the bone marrow. The treatment of choice for this disease is the enzyme L-asparaginase (ASNa
Externí odkaz:
https://doaj.org/article/08e86cc63f8f4982b8f9df5883fa395a
Autor:
John Quiñones, Rommy Díaz, Jorge F. Beltrán, Lidiana Velazquez, David Cancino, Erwin Muñoz, Patricio Dantagnan, Adrián Hernández, Néstor Sepúlveda, Jorge G. Farías
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 805 (2022)
This study aimed to analyze the effects on the lipidome of juvenile Oncorhynchus mykiss muscle fed 90% Brassica napus “rapeseed” oil and different amounts of Durvillaea antarctica “Cochayuyo” meal (1.5, 3 and 6%) as a replacement for cellulos
Externí odkaz:
https://doaj.org/article/b788eb74d5e9458d80dc7b36bb2bc2db
Autor:
Rodrigo L. Castillo, Mauricio Ibacache, Ignacio Cortínez, Catalina Carrasco-Pozo, Jorge G. Farías, Rodrigo A. Carrasco, Patricio Vargas-Errázuriz, Daniel Ramos, Rafael Benavente, Daniela Henríquez Torres, Aníbal Méndez
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2020)
Dexmedetomidine (DEX) is a highly selective α2-adrenergic agonist with sedative and analgesic properties, with minimal respiratory effects. It is used as a sedative in the intensive care unit and the operating room. The opioid-sparing effect and the
Externí odkaz:
https://doaj.org/article/a9fcd51410a84a47b75cc19e4cb847e9
Autor:
Lisandra Herrera Belén, Carlota de Oliveira Rangel-Yagui, Jorge F. Beltrán Lissabet, Brian Effer, Manuel Lee-Estevez, Adalberto Pessoa, Rodrigo L. Castillo, Jorge G. Farías
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Covalent attachment of therapeutic proteins to polyethylene glycol (PEG) is widely used for the improvement of its pharmacokinetic and pharmacological properties, as well as the reduction in reactogenicity and related side effects. This technique nam
Externí odkaz:
https://doaj.org/article/b5b6880b4a6d4c00829d7953fea85f74
Autor:
Emilio A. Herrera, Jorge G. Farías, Alejandro González-Candia, Stefania E. Short, Catalina Carrasco-Pozo, Rodrigo L. Castillo
Publikováno v:
Marine Drugs, Vol 13, Iss 2, Pp 838-860 (2015)
Intermittent hypobaric hypoxia (IH) is linked with oxidative stress, impairing cardiac function. However, early IH also activate cardio-protective mechanisms. Omega 3 fatty acids (Ω3) induce cardioprotection by reducing infarct size and reinforcing
Externí odkaz:
https://doaj.org/article/5f2087e98d6b4920b3ee2896eaab0017
Autor:
Jorge G. Farías, Víctor M. Molina, Rodrigo A. Carrasco, Andrea B. Zepeda, Elías Figueroa, Pablo Letelier, Rodrigo L. Castillo
Publikováno v:
Nutrients, Vol 9, Iss 9, p 966 (2017)
Oxidative stress (OS) refers to the imbalance between the generation of reactive oxygen species (ROS) and the ability to scavenge these ROS by endogenous antioxidant systems, where ROS overwhelms the antioxidant capacity. Excessive presence of ROS re
Externí odkaz:
https://doaj.org/article/2462d44847374a57b71abec18edaf3eb
Autor:
Pablo Letelier, Ismael Riquelme, Alfonso H. Hernández, Neftalí Guzmán, Jorge G. Farías, Juan Carlos Roa
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 5, p 791 (2016)
Biliary tract cancers (BTCs) are a group of highly aggressive malignant tumors with a poor prognosis. The current diagnosis is based mainly on imaging and intraoperative exploration due to brush cytology havinga low sensitivity and the standard marke
Externí odkaz:
https://doaj.org/article/aec79c96cccc45a0a267243a2a2269b0
Publikováno v:
Reviews in Aquaculture. 15:434-451
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62c5a342075bafe495105103d5f50f89
https://doi.org/10.1111/raq.12729
https://doi.org/10.1111/raq.12729