A new role for Zinc limitation in bacterial pathogenicity: modulation of α-hemolysin from uropathogenic Escherichia coli

Autor: Elsa Velasco, Suning Wang, Marianna Sanet, Jorge Fernández-Vázquez, Daniel Jové, Estibaliz Glaría, Annabel F. Valledor, Thomas V. O’Halloran, Carlos Balsalobre

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

Abstract Metal limitation is a common situation during infection and can have profound effects on the pathogen’s success. In this report, we examine the role of zinc limitation in the expression of a virulence factor in uropathogenic Escherichia co

Externí odkaz: https://doaj.org/article/a174d76b47b34380a2431c2c2639eec8

ppGpp, the General Stress Response Alarmone, Is Required for the Expression of the α-Hemolysin Toxin in the Uropathogenic Escherichia coli Isolate, J96

Autor: Jorge Fernández-Vázquez, Juan David Cabrer-Panes, Anna Åberg, Antonio Juárez, Cristina Madrid, Tania Gaviria-Cantin, Llorenç Fernández-Coll, Andrés Felipe Vargas-Sinisterra, Carlos Jonay Jiménez, Carlos Balsalobre

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12256
Dipòsit Digital de la UB
Universidad de Barcelona

ppGpp is an intracellular sensor that, in response to different types of stress, coordinates the rearrangement of the gene expression pattern of bacteria to promote adaptation and survival to new environmental conditions. First described to modulate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45649dcad4a5ea384b174f7286a55def

Modification of tRNALysUUU by Elongator Is Essential for Efficient Translation of Stress mRNAs

Autor: Esther Paulo, Damien Hermand, Jorge Fernández-Vázquez, Sebastian A. Leidel, Miriam Sansó, José Ayté, Miguel Ángel Rodríguez-Gabriel, Karin Buhne, Itzel Vargas-Pérez, Elena Hidalgo, Mercè Carmona

Publikováno v: PLoS Genetics
PLoS Genetics, Vol 9, Iss 7, p e1003647 (2013)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recercat. Dipósit de la Recerca de Catalunya

The Elongator complex, including the histone acetyl transferase Sin3/Elp3, was isolated as an RNA polymerase II-interacting complex, and cells deficient in Elongator subunits display transcriptional defects. However, it has also been shown that Elong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae16a3e04d6597461b52052a28371bf7
https://doi.org/10.1371/journal.pgen.1003647