Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jorge F. Quevedo"'
Autor:
Aleksandar Sekulic, Michael R. Migden, Nicole Basset-Seguin, Claus Garbe, Anja Gesierich, Christopher D. Lao, Chris Miller, Laurent Mortier, Dedee F. Murrell, Omid Hamid, Jorge F. Quevedo, Jeannie Hou, Edward McKenna, Natalie Dimier, Sarah Williams, Dirk Schadendorf, Axel Hauschild, for the ERIVANCE BCC Investigators
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background In the primary analysis of the ERIVANCE BCC trial, vismodegib, the first US Food and Drug Administration–approved Hedgehog pathway inhibitor, showed objective response rates (ORRs) by independent review facility (IRF) of 30% and
Externí odkaz:
https://doaj.org/article/369c8eef082e487e8b1ee700e6160944
Autor:
Aleksandar Sekulic, Michael R. Migden, Nicole Basset-Seguin, Claus Garbe, Anja Gesierich, Christopher D. Lao, Chris Miller, Laurent Mortier, Dedee F. Murrell, Omid Hamid, Jorge F. Quevedo, Jeannie Hou, Edward McKenna, Natalie Dimier, Sarah Williams, Dirk Schadendorf, Axel Hauschild, for the ERIVANCE BCC Investigators
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-1 (2019)
Following publication of the original article [1], it was reported that the legend for Fig. 1 was incomplete. The complete figure legend is:
Externí odkaz:
https://doaj.org/article/c7f86cdcb25043d29d5876749e8c0149
Autor:
Scott M. Dehm, Liewei Wang, Joshua M. Lang, Kevin A.T. Silverstein, Eric D. Wieben, Jin Jen, Brian A. Costello, Henry C. Pitot, Jorge F. Quevedo, Bruce W. Eckloff, Peter T. Vedell, Haojie Huang, Rafael Jimenez, Ho Thai, Hugues Sicotte, Liguo Wang, Rachel E. Carlson, Winston Tan, Tyson Clark, Ting Hon, Elizabeth Tseng, Yingming Li, Jamie M. Sperger, Rendong Yang, Christine Henzler, Jamie L. Van Etten, David W. Hillman, Yeung Ho, Manish Kohli
Purpose: Androgen receptor (AR) variant AR-V7 is a ligand-independent transcription factor that promotes prostate cancer resistance to AR-targeted therapies. Accordingly, efforts are under way to develop strategies for monitoring and inhibiting AR-V7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875c67d4c730ffa27f30addd230041a8
https://doi.org/10.1158/1078-0432.c.6525402
https://doi.org/10.1158/1078-0432.c.6525402
Autor:
Scott M. Dehm, Liewei Wang, Joshua M. Lang, Kevin A.T. Silverstein, Eric D. Wieben, Jin Jen, Brian A. Costello, Henry C. Pitot, Jorge F. Quevedo, Bruce W. Eckloff, Peter T. Vedell, Haojie Huang, Rafael Jimenez, Ho Thai, Hugues Sicotte, Liguo Wang, Rachel E. Carlson, Winston Tan, Tyson Clark, Ting Hon, Elizabeth Tseng, Yingming Li, Jamie M. Sperger, Rendong Yang, Christine Henzler, Jamie L. Van Etten, David W. Hillman, Yeung Ho, Manish Kohli
Supplementary Table 1: Baseline Characteristics of the Patients; Supplementary Table 2: Baseline RNA-seq Expression Levels for AR/ARVs (spliced reads per million); Supplementary Table 3: TaqMan Gene Expression Assays with Circulating Tumor Cells; Sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ffdf0b0351ff1db0ee720d4361162d
https://doi.org/10.1158/1078-0432.22463442.v1
https://doi.org/10.1158/1078-0432.22463442.v1
Autor:
Jorge F. Quevedo, James R. Cerhan, Rhea Kohli, Manish Kohli, Ben Y. Zhang, Douglas W. Mahoney, Brian A. Costello, Shaun M. Riska
Publikováno v:
BJU International. 119:489-495
Objectives To evaluate the prognostic significance of germline variation in candidate genes in patients with castration-resistant prostate cancer (CRPC). Methods Germline DNA was extracted from peripheral blood mononuclear cells of patients with CRPC
Autor:
Hugues Sicotte, Eric D. Wieben, Liewei Wang, Rafael E. Jimenez, Henry C. Pitot, Yeung Ho, Bruce W. Eckloff, Ho Thai, Liguo Wang, Jamie M. Sperger, Joshua M. Lang, David W. Hillman, Haojie Huang, Elizabeth Tseng, Rendong Yang, Jin Jen, Yingming Li, Jamie L. Van Etten, Jorge F. Quevedo, Peter T. Vedell, Manish Kohli, Winston Tan, Christine Henzler, Kevin A. T. Silverstein, Rachel Carlson, Brian A. Costello, Ting Hon, Scott M. Dehm, Tyson A. Clark
Purpose: Androgen receptor (AR) variant AR-V7 is a ligand-independent transcription factor that promotes prostate cancer resistance to AR-targeted therapies. Accordingly, efforts are under way to develop strategies for monitoring and inhibiting AR-V7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc387eee52e6b9a39a1bc34da02bd6c3
https://europepmc.org/articles/PMC5644285/
https://europepmc.org/articles/PMC5644285/
Autor:
Judith S. Kaur, Vera J. Suman, Edward T. Creagan, Jorge F. Quevedo, Svetomir N. Markovic, Wendy K. Nevala, Robert R. McWilliams, Matthew S. Block, Lisa A. Kottschade
Publikováno v:
Melanoma Research. 21:438-445
Thus far, peptide vaccines used to stimulate tumor-specific immune responses in patients with melanoma have been largely unsuccessful. Granulocyte-macrophage colony-stimulating factor and interleukin-2 are immune-potentiating cytokines that have impr
Autor:
Anthony M. Joshua, Grazia Ambrosini, Kristin K. Ancell, Christopher D. Lao, Jorge F. Quevedo, Austin Doyle, Gerald P. Linette, Thomas F. Gajewski, Jeffrey A. Sosman, Jedd D. Wolchok, Brian P. Marr, Joseph P. Erinjeri, Mark J. Bluth, Karl D. Lewis, Katherine S. Panageas, Jose Lutzky, Gary K. Schwartz, Paul B. Chapman, Takami Sato, Mohammed M. Milhem, David H. Lawson, Ragini R. Kudchadkar, Mark A. Dickson, David H. Abramson, Mark R. Albertini, Patrick J. Flynn, Richard D. Carvajal, Cyrus V. Hedvat
Uveal melanoma is characterized by mutations in GNAQ and GNA11, resulting in mitogen-activated protein kinase pathway activation.To assess the efficacy of selumetinib, a selective, non-adenosine triphosphate competitive inhibitor of MEK1 and MEK2, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502877e6bcc25e72be50fe0d404ac760
https://europepmc.org/articles/PMC4249701/
https://europepmc.org/articles/PMC4249701/
Autor:
Christopher D. Lao, N. Basset Seguin, Laurent Mortier, H. Omid, Jorge F. Quevedo, Michael R. Migden, Aleksandar Sekulic, Jeannie Hou, Dedee F. Murrell, Anja Gesierich, Christopher J. Miller, Claus Garbe, Huibin Yue, Dirk Schadendorf
Publikováno v:
Annales de Dermatologie et de Vénéréologie. 140:S392-S393
Autor:
Michael R. Migden, Dirk Schadendorf, Nicole Basset-Seguin, Christopher J. Miller, Omid Hamid, Jorge F. Quevedo, Anja Gesierich, Christopher D. Lao, Aleksandar Sekulic, Jeannie Hou, Dedee F. Murrell, M. Tripathi, Laurent Mortier, Claus Garbe
Publikováno v:
Annales de Dermatologie et de Vénéréologie. 141:S288
Introduction Une activation anormale de la voie de signalisation Hedgehog (HP) est impliquee dans la physiopathologie du carcinome basocellulaire (CBC). Dans l’essai ERIVANCE BCC, le vismodegib, premier inhibiteur de la voie Hedgehog (HPI) autorise