Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Jorge F Giani"'
Autor:
Carolina Dalmasso, Nermin S. Ahmed, Sundus Ghuneim, Cole Cincinelli, Jaqueline R. Leachman, Jorge F. Giani, Lisa Cassis, Analia S. Loria
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 1 (2024)
Background We have previously reported that male mice exposed to maternal separation and early weaning (MSEW), a model of early life stress, show sympathetic activation and increased blood pressure in response to a chronic high‐fat diet. The goal o
Externí odkaz:
https://doaj.org/article/92cac2aa80624d0499c33c9f90306db8
Autor:
Duo-Yao Cao, Suguru Saito, Luciana C. Veiras, Derick Okwan-Duodu, Ellen A. Bernstein, Jorge F. Giani, Kenneth E. Bernstein, Zakir Khan
Publikováno v:
Cellular & Molecular Biology Letters, Vol 25, Iss 1, Pp 1-12 (2020)
Abstract Angiotensin-converting enzyme (ACE), a dicarboxypeptidase, plays a major role in the regulation of blood pressure by cleaving angiotensin I into angiotensin II (Ang II), a potent vasoconstrictor. Because of its wide substrate specificity and
Externí odkaz:
https://doaj.org/article/94854cb79e4947a19e3ca3da80b071fd
Autor:
Zhenzi Peng, Cuiwei Liu, Aaron R. Victor, Duo-Yao Cao, Luciana C. Veiras, Ellen A. Bernstein, Zakir Khan, Jorge F. Giani, Xiaojiang Cui, Kenneth E. Bernstein, Derick Okwan-Duodu
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Granulocytes are key players in cancer metastasis. While tumor-induced de novo expansion of immunosuppressive myeloid-derived suppressor cells (MDSCs) is well-described, the fate and contribution of terminally differentiated mature neutrophils to the
Externí odkaz:
https://doaj.org/article/172498add4db402ab102601c328e4a79
Autor:
Carolina Dalmasso, Alejandro R. Chade, Mariela Mendez, Jorge F. Giani, Gregory J. Bix, Kuey C. Chen, Analia S. Loria
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/124e672320134723a144f3ee3802580b
Autor:
Carolina Dalmasso, Alejandro R. Chade, Mariela Mendez, Jorge F. Giani, Gregory J. Bix, Kuey C. Chen, Analia S. Loria
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Environmental stress during early life is an important factor that affects the postnatal renal development. We have previously shown that male rats exposed to maternal separation (MatSep), a model of early life stress, are normotensive but display a
Externí odkaz:
https://doaj.org/article/312347319bdd4216ada7dcf87909b851
Autor:
Carolina Dalmasso, Jacqueline R. Leachman, Charles M. Ensor, Frederique B. Yiannikouris, Jorge F. Giani, Lisa A. Cassis, Analia S. Loria
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 23 (2019)
Background We have previously reported that female mice exposed to maternal separation and early weaning (MSEW), a model of early life stress, show exacerbated diet‐induced obesity associated with hypertension. The goal of this study was to test wh
Externí odkaz:
https://doaj.org/article/fa7e187606cb430f895dab134a3e251e
Autor:
DuoYao Cao, Zakir Khan, Xiaomo Li, Suguru Saito, Ellen A Bernstein, Aaron R Victor, Faizan Ahmed, Aoi O Hoshi, Luciana C Veiras, Tomohiro Shibata, Mingtian Che, Lei Cai, Ryan E Temel, Jorge F Giani, Daniel J Luthringer, Ajit S Divakaruni, Derick Okwan-Duodu, Kenneth E Bernstein
Publikováno v:
Cardiovascular Research.
Aims The metabolic failure of macrophages to adequately process lipid is central to the etiology of atherosclerosis. Here, we examine the role of macrophage angiotensin converting enzyme (ACE) in a mouse model of PCSK9 induced atherosclerosis. Method
Autor:
Tomohiro Shibata, Duo-Yao Cao, Tahir B. Dar, Faizan Ahmed, Shabir A. Bhat, Luciana C. Veiras, Ellen A. Bernstein, Abdul Arif Khan, Manita Chaum, Stephen L. Shiao, Warren G. Tourtellotte, Jorge F. Giani, Kenneth E. Bernstein, Xiaojiang Cui, Eric Vail, Zakir Khan
Publikováno v:
Cancers; Volume 14; Issue 21; Pages: 5273
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive disease with poor prognosis, which is mainly due to drug resistance. The biology determining the response to chemo-radiotherapy in HNSCC is poorly understood. Using clinical samples
Autor:
Jorge F Giani, Luciana C Veiras, Ellen Bernstein, Duoyao Cao, Zakir Khan, Kenneth E Bernstein
Publikováno v:
Hypertension. 79
We showed that IL-1β derived from renal tubular epithelial cells initiates the inflammatory response that promotes salt sensitivity during diabetes. Yet, the intracellular mechanism that mediates IL-1β synthesis by tubular cells is unknown. We hypo
Autor:
Alicia A. McDonough, Kenneth E. Bernstein, Susan B. Gurley, Zhidan Xiang, Jorge F. Giani, Jonathan W. Nelson, Joshua A. Robertson, Donna L. Ralph
Publikováno v:
Am J Physiol Renal Physiol
The renal nephron consists of a series of distinct cell types that function in concert to maintain fluid and electrolyte balance and blood pressure. The renin-angiotensin system (RAS) is central to Na(+) and volume balance. We aimed to determine how