Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Jorge E. Jalil"'
Autor:
Jorge E. Jalil, Luigi Gabrielli, María Paz Ocaranza, Paul MacNab, Rodrigo Fernández, Bruno Grassi, Paulina Jofré, Hugo Verdejo, Monica Acevedo, Samuel Cordova, Luis Sanhueza, Douglas Greig
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4407 (2024)
This review examines the impact of obesity on the pathophysiology of heart failure with preserved ejection fraction (HFpEF) and focuses on novel mechanisms for HFpEF prevention using a glucagon-like peptide-1 receptor agonism (GLP-1 RA). Obesity can
Externí odkaz:
https://doaj.org/article/efe8ad8cc25f49fc8cefdf023d601dfd
Autor:
Maria Paz Ocaranza, Patricio Valderas, Jackeline Moya, Luigi Gabrielli, Iván Godoy, Samuel Córdova, Paul Mac Nab, Lorena García, Luis Farías, Jorge E. Jalil
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-12 (2020)
Abstract Background The intracellular ROCK signaling pathway is an important modulator of blood pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased. Besides, in preclinical models of diabetes, ROCK activation has
Externí odkaz:
https://doaj.org/article/4e2bcc6c0810436993c1b1ce3b0fda7c
Autor:
Felipe Contreras-Briceño, Sebastián Herrera, Julian Vega-Adauy, Manuel Salinas, María Paz Ocaranza, Jorge E. Jalil, Jorge Mandiola, Lorena García, Mario Chiong, Pablo F. Castro, Sergio Lavandero, Luigi Gabrielli
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Introduction: An increased risk of atrial fibrillation (AF) has been demonstrated in high-performance athletes. Soluble vascular adhesion molecule-1 (sVCAM-1), a biomarker involved in inflammation and cardiac remodeling, is associated with the develo
Externí odkaz:
https://doaj.org/article/a7f77ab658454e38a792bc7f5c527b4c
Autor:
Maria Paz Ocaranza, Jorge E. Jalil, Rodrigo Altamirano, Ana de León, Jackeline Moya, Alejandra Lonis, Luigi Gabrielli, Paul Mac Nab, Samuel Córdova, Alejandro Paredes, Ismael Vergara, Alex Bittner, Karime Sabat, Karla Pastorini
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Reverse remodeling is a clinically relevant endpoint in heart failure with reduced ejection fraction (HFrEF). Rho-kinase (ROCK) signaling cascade activation correlates with cardiac remodeling and left ventricular (LV) systolic dysfunction
Externí odkaz:
https://doaj.org/article/6be449dced514ba88094fb492a1bc5b8
Autor:
Felipe Contreras-Briceño, Julián Vega, Jorge Mandiola, María Paz Ocaranza, Sebastián Herrera, Manuel Salinas, Rodrigo Fernández, Jorge E. Jalil, Sergio Lavandero, Mario Chiong, Paz Godoy, Pablo F. Castro, Marta Sitges, Luigi Gabrielli
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 10, p 118 (2021)
This single-blind and cross-sectional study evaluated the role of Rho-kinase (ROCK) as a biomarker of the cardiovascular remodelling process assessed by echocardiography in competitive long-distance runners (LDRs) during the training period before a
Externí odkaz:
https://doaj.org/article/5ee13dd1905e454b8bc51ad28be736e3
Autor:
María Paz Ocaranza, Jorge E. Jalil
Publikováno v:
International Journal of Hypertension, Vol 2012 (2012)
Despite reduction in cardiovascular (CV) events and end-organ damage with the current pharmacologic strategies, CV disease remains the primary cause of death in the world. Pharmacological therapies based on the renin angiotensin system (RAS) blockade
Externí odkaz:
https://doaj.org/article/0b54ce7dd7c7412aba39d3c6756018a6
Autor:
Jorge E. Jalil, María Paz Ocaranza, Ulises Novoa, David Mondaca-Ruff, Italo Mora, Patricio Araos, Cristian Yañez
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 26:724-735
Background: Thiazides are one of the most common antihypertensive drugs used for hypertension treatment and hydrochlorothiazide (HCTZ) is the most frequently used diuretic for hypertension treatment. The Rho/Rho-kinase (ROCK) path plays a key functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a245a97b208dd7b3eefc698a048b2cb
https://doi.org/10.1177/10742484211053109
https://doi.org/10.1177/10742484211053109
Autor:
Marcelo Llancaqueo, Rodrigo Jaimovich, Jaime Álvarez, Douglas Greig, Teresa Massardo, Felipe Castañía, Jorge E. Jalil, Paul McNab
Publikováno v:
Revista chilena de cardiología v.40 n.2 2021
SciELO Chile
CONICYT Chile
instacron:CONICYT
SciELO Chile
CONICYT Chile
instacron:CONICYT
RESUMEN: La cardiomiopatía amiloide por transtiretina (CATTR) es una enfermedad caracterizada por depósito extracelular de fibrillas amiloides en el miocardio, a partir de transtiretina mal plegada, generando una miocardiopatía restrictiva. Esta p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c6a48d00b76d936d856f30a414bc55
https://doi.org/10.4067/s0718-85602021000200148
https://doi.org/10.4067/s0718-85602021000200148
Autor:
María Paz Ocaranza, Jorge E. Jalil, Alejandra Lonis, Jackeline Moya, Luigi Gabrielli, Attilio Rigotti
Publikováno v:
Revista chilena de cardiología v.39 n.1 2020
SciELO Chile
CONICYT Chile
instacron:CONICYT
SciELO Chile
CONICYT Chile
instacron:CONICYT
Resumen: Introducción: Los ratones SR-B1 KO/ApoER6 1h/h que son alimentados con una dieta rica en grasas saturadas, desarrollan enfermedad coronaria aterosclerótica severa, complicaciones isquémicas e insuficiencia cardíaca, con alta mortalidad.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e688cfc3dce8a5336223133a43fd9ca9
https://doi.org/10.4067/s0718-85602020000100024
https://doi.org/10.4067/s0718-85602020000100024
Autor:
Sergio Lavandero, Jaime A. Riquelme, María Paz Ocaranza, Mario Chiong, Andrés Ramírez-Reyes, Jorge E. Jalil, Andrea Ramírez-Sagredo
Publikováno v:
Revista chilena de cardiología. 39:66-74
In December 2019, a new type of coronavirus emerged in the city of Wuhan, China This novel virus has unleashed a pandemic that has inflicted a considerable impact on public health and the economy and has therefore become a severe concern worldwide Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad445e9cb22894b3fa138cc8f569252
https://doi.org/10.4067/s0718-85602020000100066
https://doi.org/10.4067/s0718-85602020000100066