Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jorge Dominguez-Andres"'
Autor:
Bowen Zhang, Simone J.C.F.M Moorlag, Jorge Dominguez-Andres, Özlem Bulut, Gizem Kilic, Zhaoli Liu, Reinout van Crevel, Cheng-Jian Xu, Leo A.B. Joosten, Mihai G. Netea, Yang Li
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 7 (2022)
Trained immunity refers to the long-lasting memory traits of innate immunity. Recent studies have shown that trained immunity is orchestrated by sustained changes in epigenetic marks and metabolic pathways, leading to an altered transcriptional respo
Externí odkaz:
https://doaj.org/article/d512aa7931254f3fb5ac7050959df3f4
Autor:
Büsranur Geckin, Martijn Zoodsma, Gizem Kilic, Priya A. Debisarun, Srabanti Rakshit, Vasista Adiga, Asma Ahmed, Chaitra Parthiban, Nirutha Chetan Kumar, George D’Souza, Marijke P Baltissen, Joost H A Martens, Jorge Dominguez Andres, Yang Li, Annapurna Vyakarnam, Mihai G Netea
During the COVID-19 pandemic, large differences in susceptibility and mortality due to SARS-CoV-2 infection have been reported between populations in Europe and South Asia. While both host and environmental factors (including BCG vaccination) have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466020b6ef1aa271e6524a5d7434bd96
https://doi.org/10.1101/2022.08.30.505791
https://doi.org/10.1101/2022.08.30.505791
Autor:
Bowen Zhang, Simone J.C.F.M Moorlag, Jorge Dominguez-Andres, Özlem Bulut, Gizem Kilic, Zhaoli Liu, Reinout van Crevel, Cheng-Jian Xu, Leo A.B. Joosten, Mihai G. Netea, Yang Li
Publikováno v:
Journal of Clinical investigation
Journal of Clinical Investigation, 132, 7
Journal of Clinical Investigation, 132
Journal of Clinical Investigation, 132, 7
Journal of Clinical Investigation, 132
Contains fulltext : 248728.pdf (Author’s version preprint ) (Closed access) Trained immunity refers to the long-lasting memory traits of innate immunity. Recent studies have shown that trained immunity is orchestrated by sustained changes in epigen
Autor:
Anaísa V. Ferreira, Juan Carlos Alarcon-Barrera, Jorge Domínguez-Andrés, Özlem Bulut, Gizem Kilic, Priya A. Debisarun, Rutger J. Röring, Hatice N. Özhan, Eva Terschlüsen, Athanasios Ziogas, Sarantos Kostidis, Yassene Mohammed, Vasiliki Matzaraki, George Renieris, Evangelos J. Giamarellos-Bourboulis, Mihai G. Netea, Martin Giera
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Infections and vaccines can induce enhanced long-term responses in innate immune cells, establishing an innate immunological memory termed trained immunity. Here, we show that monocytes with a trained immunity phenotype, due to exposure to t
Externí odkaz:
https://doaj.org/article/8d55ada0d53e44d18afec045e805fbf3
Autor:
Jéssica Cristina dos Santos, María Moreno, Lisa U. Teufel, Sofía Chilibroste, Samuel T. Keating, Laszlo Groh, Jorge Domínguez-Andrés, David L. Williams, Zuchao Ma, Douglas W. Lowman, Harry E. Ensley, Boris Novakovic, Fátima Ribeiro-Dias, Mihai G. Netea, José A. Chabalgoity, Leo A.B. Joosten
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113932- (2024)
Summary: Innate immune cells can undergo long-term functional reprogramming after certain infections, a process called trained immunity (TI). Here, we focus on antigens of Leishmania braziliensis, which induced anti-tumor effects via trained immunity
Externí odkaz:
https://doaj.org/article/8ebddf1993314afea0c3d957a5bb75f1
Autor:
Büsra Geckin, Gizem Kilic, Priya A. Debisarun, Konstantin Föhse, Azahara Rodríguez-Luna, Pablo Fernández-González, Ana López Sánchez, Jorge Domínguez-Andrés
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The proper functioning of the immune system depends on an appropriate balance between pro-inflammation and anti-inflammation. When the balance is disrupted and the system is excessively biased towards inflammation, immune responses cannot return with
Externí odkaz:
https://doaj.org/article/c6fc887702f84f12bac957ab23048db9
Autor:
Elisabeth A. Dulfer, Büsra Geckin, Esther J.M. Taks, Corine H. GeurtsvanKessel, Helga Dijkstra, Liesbeth van Emst, Christa E. van der Gaast – de Jongh, Petra C. Koopmans, Jorge Domínguez-Andrés, Reinout van Crevel, Josephine S. van de Maat, Marien I. de Jonge, Mihai G. Netea
Publikováno v:
The Lancet Regional Health. Europe, Vol 30, Iss , Pp 100669- (2023)
Externí odkaz:
https://doaj.org/article/a68b1ecff69f41cbbd978834e38da1d3
Autor:
Anaísa V. Ferreira, Sarantos Kostidis, Laszlo A. Groh, Valerie A.C.M. Koeken, Mariolina Bruno, Ilayda Baydemir, Gizem Kilic, Özlem Bulut, Theano Andriopoulou, Victoria Spanou, Kalliopi D. Synodinou, Theologia Gkavogianni, Simone J.C.F.M. Moorlag, L. Charlotte de Bree, Vera P. Mourits, Vasiliki Matzaraki, Werner J.H. Koopman, Frank L. van de Veerdonk, Georgios Renieris, Martin Giera, Evangelos J. Giamarellos-Bourboulis, Boris Novakovic, Jorge Domínguez-Andrés
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112658- (2023)
Summary: Itaconate is an immunomodulatory metabolite produced by immune cells under microbial stimulation and certain pro-inflammatory conditions and triggers antioxidant and anti-inflammatory responses. We show that dimethyl itaconate, a derivative
Externí odkaz:
https://doaj.org/article/6e7649ccdf4846afb0796f373689a5d6
Autor:
Lidia Feo-Lucas, Cristina Godio, María Minguito de la Escalera, Natalia Alvarez-Ladrón, Laura H. Villarrubia, Adrián Vega-Pérez, Leticia González-Cintado, Jorge Domínguez-Andrés, Belén García-Fojeda, Carlos Montero-Fernández, Cristina Casals, Chiara Autilio, Jesús Pérez-Gil, Georgiana Crainiciuc, Andrés Hidalgo, María López-Bravo, Carlos Ardavín
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Respiratory disorders caused by allergy have been associated to bronchiolar inflammation leading to life-threatening airway narrowing. However, whether airway allergy causes alveolar dysfunction contributing to the pathology of allergic asthma remain
Externí odkaz:
https://doaj.org/article/3f66a8b083034c48bba53e50f4d065f2
Autor:
Leticia Martín-Cruz, Alba Angelina, Ilayda Baydemir, Özlem Bulut, José Luis Subiza, Mihai G. Netea, Jorge Domínguez-Andrés, Oscar Palomares
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionRecurrent urinary tract infections (RUTIs) and recurrent vulvovaginal candidiasis (RVVCs) represent major healthcare problems all over the world. Antibiotics and antifungals are widely used for such infectious diseases, which is linked wi
Externí odkaz:
https://doaj.org/article/c84bade010c84df7b90b26c0769d38a0