Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Jorge C G Blanco"'
Autor:
Jorge C G Blanco, Lori M Cullen, Arash Kamali, Fatoumata Y D Sylla, Marina S Boukhvalova, Trudy G Morrison
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1009856 (2021)
Maternal anti-respiratory syncytial virus (RSV) antibodies acquired by the fetus through the placenta protect neonates from RSV disease through the first weeks of life. In the cotton rat model of RSV infections, we previously reported that immunizati
Externí odkaz:
https://doaj.org/article/2c541828bf034101ab43c987c5ecb6a9
Autor:
Kari Ann Shirey, Wendy Lai, Lindsey J Brown, Jorge C G Blanco, Robert Beadenkopf, Yajing Wang, Stefanie N Vogel, Greg A Snyder
Publikováno v:
Innate Immunity, Vol 26 (2020)
TLRs are a family of PRRs that respond to PAMPs or host-derived Danger-Associated Molecular Patterns (DAMPs) to initiate host inflammation and immune responses. TLR dimerization and recruitment of adapter molecules is critical for intracellular signa
Externí odkaz:
https://doaj.org/article/e8c8f57a4e2b417bb920ccf0d3a1949e
Autor:
Mira C Patel, Wei Wang, Lioubov M Pletneva, Seesandra V Rajagopala, Yi Tan, Tina V Hartert, Marina S Boukhvalova, Stefanie N Vogel, Suman R Das, Jorge C G Blanco
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166336 (2016)
In recent years, there has been a significant increase in detection of Enterovirus D-68 (EV-D68) among patients with severe respiratory infections worldwide. EV-D68 is now recognized as a re-emerging pathogen; however, due to lack of a permissive ani
Externí odkaz:
https://doaj.org/article/065d7e0b51a84a78b777c7ffd4826168
Autor:
Karen J. Gonzalez, Kevin C. Yim, Jorge C. G. Blanco, Marina S. Boukhvalova, Eva-Maria Strauch
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Numerous enveloped viruses, such as coronaviruses, influenza, and respiratory syncytial virus (RSV), utilize class I fusion proteins for cell entry. During this process, the proteins transition from a prefusion to a postfusion state, undergoing subst
Externí odkaz:
https://doaj.org/article/06d092ee163546c58ed0ec67d45823c7
Autor:
Marc P Hübner, Kristin E Killoran, Michael Rajnik, Samuel Wilson, Kevin C Yim, Marina N Torrero, Christopher P Morris, Boris Nikonenko, Jorge C G Blanco, Val G Hemming, Edward Mitre
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 12, p e1970 (2012)
Chronic helminth infections induce a Th2 immune shift and establish an immunoregulatory milieu. As both of these responses can suppress Th1 immunity, which is necessary for control of Mycobacterium tuberculosis (MTB) infection, we hypothesized that c
Externí odkaz:
https://doaj.org/article/91af0db8809348e4890ab2cfcc92868c
Autor:
Marina S. Boukhvalova, Emma Mortensen, Jessica Caple, John Joseph, Fatoumata Sylla, Arash Kamali, Daniel Stylos, Diego Lopez, Thomas March, Kevin Matthew Byrd, Gregory A. Prince, Ariel Arndt, Adriana Kajon, Jorge C. G. Blanco
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Heterogeneity of COVID-19 manifestations in human population is vast, for reasons unknown. Cotton rats are a clinically relevant small animal model of human respiratory viral infections. Here, we demonstrate for the first time that SARS-CoV-
Externí odkaz:
https://doaj.org/article/c6aa0ff1820c498eafdc7b35ad72ded1
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Alzheimer’s disease (AD) and multiple sclerosis (MS) are two CNS disorders affecting millions of people, for which no cure is available. AD is usually diagnosed in individuals age 65 and older and manifests with accumulation of beta amyloid in the
Externí odkaz:
https://doaj.org/article/1a75b650c493413a9c2eaa386bd73e84
Autor:
Jorge C. G. Blanco, Lori M. Cullen, Arash Kamali, Fatoumata Y. D. Sylla, Zenab Chinmoun, Marina S. Boukhvalova, Trudy G. Morrison
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 7 (2022)
Maternal anti-respiratory syncytial virus (RSV) antibodies protect neonates from RSV disease throughout first weeks of life. Previous studies of maternal immunization in cotton rats showed that a single immunization during pregnancy of RSV-primed dam
Externí odkaz:
https://doaj.org/article/57edfe4a2b5540ba9bda3b8eb3e892d2
Autor:
Jorge C. G. Blanco, Lori M. Cullen, Arash Kamali, Fatouomata Y. D. Sylla, Marina S. Boukhvalova, Trudy G. Morrison
Publikováno v:
Viruses, Vol 15, Iss 6, p 1305 (2023)
Respiratory syncytial virus (RSV) is a significant threat to elderly populations and repeated infections that occur throughout life are poorly protective. To assess the role of prior RSV infections as well as elderly immune senescence on vaccine effi
Externí odkaz:
https://doaj.org/article/ce843923b5b84c6f969e9a2b6a6b1bd9
Publikováno v:
Viruses, Vol 15, Iss 2, p 476 (2023)
Human metapneumovirus (hMPV) is an important cause of respiratory disease in immunocompromised individuals, yet hMPV infection has not been modeled before in immunocompromised animals. In this work, cotton rats S. hispidus immunosuppressed by cycloph
Externí odkaz:
https://doaj.org/article/72300d55b1a9440fad55fae81e7ca724