Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jorge Barroso-Aranda"'
Autor:
James J DiNicolantonio, Mark F McCarty, Jorge Barroso-Aranda, Simon Assanga, Lidianys Maria Lewis Lujan, James H O'Keefe
Publikováno v:
Open Heart, Vol 8, Iss 1 (2021)
Externí odkaz:
https://doaj.org/article/02e053cbef2e431ebc090dc72f7dda26
Publikováno v:
Immunology Letters
Highlights • Previous research demonstrates that, in clinically relevant concentrations, azithromycin can boost the ability of RNA viruses to induce type 1 interferon by amplifying the expression and virally-mediated activation of MDA5. • O-GlcNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b20975fdad5fea1df7e343c67f0f027
http://europepmc.org/articles/PMC7521214
http://europepmc.org/articles/PMC7521214
Publikováno v:
Medical Hypotheses
Counterproductive lung inflammation and dysregulated thrombosis contribute importantly to the lethality of advanced COVID-19. Adenosine A2A receptors (A2AR), expressed by a wide range of immune cells, as well as endothelial cells and platelets, exert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9c3bfa9ad7d912d3177e1702073da7
https://pubmed.ncbi.nlm.nih.gov/32650197
https://pubmed.ncbi.nlm.nih.gov/32650197
Autor:
Lidianys Lewis Lujan, James J DiNicolantonio, Mark F. McCarty, Jorge Barroso-Aranda, Simon Bernard Iloki Assanga, James H. O'Keefe
Publikováno v:
Open Heart, Vol 8, Iss 1 (2021)
Open Heart
Open Heart
Upregulated transforming growth factor-beta (TGFβ) signalling, driving mesenchymal cells to increase their production of ground substance and undergo a transition to a myofibroblast phenotype, is believed to play a pathogenic role in diverse fibroti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a6093ca1a21f5965a73c912b7bb38c
https://doi.org/10.1136/openhrt-2021-001663
https://doi.org/10.1136/openhrt-2021-001663
Publikováno v:
Medical Hypotheses. 74:370-373
Recent studies show that ingestion of flavanol-rich cocoa powder provokes increased endothelial production of nitric oxide - an effect likely mediated by epicatchin - and thus may have considerable potential for promoting vascular health. The Kuna In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a39ec785762df8c2af363525a3690ee
https://doi.org/10.1016/j.mehy.2008.09.060
https://doi.org/10.1016/j.mehy.2008.09.060
Publikováno v:
Medical Hypotheses. 73:824-834
Reduced folates have been shown to reconstitute the proper activity of "uncoupled" endothelial nitric oxide synthase in inflamed endothlelium. There is recent evidence that this phenomenon may reflect an ability of reduced folates to scavenge peroxyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea756f8cb5da65671683a772a529df15
https://doi.org/10.1016/j.mehy.2008.09.058
https://doi.org/10.1016/j.mehy.2008.09.058
Publikováno v:
Medical Hypotheses. 73:619-622
From the standpoint of promoting leanness, exercise is of most value if oxidation of stored fat is maximized during and following the exercise sessions. Bahadori has proposed that this can best be achieved if prolonged exercise of moderate intensity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a6ef31f787db4d32a5ed45c653446b
https://doi.org/10.1016/j.mehy.2008.09.063
https://doi.org/10.1016/j.mehy.2008.09.063
Publikováno v:
Medical Hypotheses. 72:125-128
summary Recent studies confirm that dietary methionine restriction increases both mean and maximal lifespan in rats and mice, achieving ‘‘aging retardant” effects very similar to those of caloric restriction, including a suppression of mitochon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51be2cd6724e7d9991808cc3e47acd68
https://doi.org/10.1016/j.mehy.2008.07.044
https://doi.org/10.1016/j.mehy.2008.07.044
Publikováno v:
Medical Hypotheses. 72:29-33
In aging rats, lipoic acid exerts a "rejuvenative" impact on mitochondria in various tissues, boosting mitochondrial membrane potential and oxygen consumption, while decreasing mitochondrial production of oxidants. A likely explanation for this pheno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef57312aa021709c4e3edfa570571f2
https://doi.org/10.1016/j.mehy.2008.07.043
https://doi.org/10.1016/j.mehy.2008.07.043
Publikováno v:
Medical Hypotheses. 70:419-423
Summary The ability of metronomic chemotherapy to induce endothelial apoptosis has been traced to increased endothelial expression of thrombospondin-1, which activates endothelial CD36 receptors, triggering the extrinsic apoptotic pathway. Endothelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09728219db19aad542020ae6684cf68d
https://doi.org/10.1016/j.mehy.2006.12.064
https://doi.org/10.1016/j.mehy.2006.12.064