Immune Checkpoint Blockade and Immune Monitoring

Autor: Luiz R. Travassos, Jorge Augusto Borin Scutti, Luiz M. Vence

Publikováno v: Immunoregulatory Aspects of Immunotherapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed5cadb5f8c9d7a63ccf8e557b05d7a
https://doi.org/10.5772/intechopen.74688

Anti‐metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10

Autor: Filipe M. de Melo, Maria A. Juliano, Amanda Campelo L Melo, Priscila Henriques da Silva, Elaine G. Rodrigues, Catarina J.M. Braga, Luís Carlos de Souza Ferreira, Jorge Augusto Borin Scutti, Niels Olsen Saraiva Câmara, Mariana Fernandes de Souza, Dario S. Zamboni, Samanta Lopes Tomaz, Clarice Silvia Taemi Origassa, Luiz R. Travassos, Felipe V. Pereira, Karina P. Gimenes, Juliana Terzi Maricato

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Current therapies against malignant melanoma generally fail to increase survival in most patients, and immunotherapy is a promising approach as it could reduce the dosage of toxic therapeutic drugs. In the present study, we show that an immunotherape

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6bcb39b25f4af49b7d84fd8131a0bb
https://doi.org/10.1038/icb.2014.74

Durable Responses with Ipilimumab Plus Lenalidomide after Allogeneic and Autologous Stem Cell Transplantation for Patients with Lymphoid Malignancies

Autor: Mariana Pineda, Alison M. Gulbis, Denái R. Milton, Shalini S. Yadav, Jorge Augusto Borin Scutti, Elias Jabbour, Luis M Vence, James P. Allison, Courtney Nicholas, Issa F. Khouri, Padmanee Sharma, Roland L. Bassett

Publikováno v: Blood. 132:4585-4585

Background: Prevention or treatment of relapsed lymphoid malignancies after SCT requires novel strategies. We previously reported on safety and early responses of ipilimumab combined with lenalidomide in 16 treated patients (pts.) (Khouri et al. Clin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f89c046e8711b1c060a6102c8c293507
https://doi.org/10.1182/blood-2018-99-117814

Melanoma: Perspectives of a Vaccine Based on Peptides

Autor: Denise C. Arruda, Mariana H. Massaoka, Aline Nogueira Rabaca, Natalia Girola, Camyla F. Farias, Jorge Augusto Borin Scutti, Luiz R. Travassos, Alisson L. Matsuo, Carlos R. Figueiredo

Publikováno v: Molecular Vaccines ISBN: 9783709114186

Anti-tumor peptides have been identified in internal sequences of immunoglobulins, mainly the complementarity determining regions (CDRs), and also as sequences of signaling proteins. The in vitro effects of these peptides against several tumor cell l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ffae53f4370fc03f9a27bb6c6bf614f2
https://doi.org/10.1007/978-3-7091-1419-3_24

Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo

Autor: Mariana H. Massaoka, Paulete Romoff, Camyla F. Farias, Oriana A. Fávero, João Henrique G. Lago, Luiz R. Travassos, Jorge Augusto Borin Scutti, Natalia Girola, Alisson L. Matsuo, Carlos R. Figueiredo, Denise C. Arruda, Marcelo J. P. Ferreira

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38698 (2012)
Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
PLoS ONE

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Background: Malignant melanoma is a deadly type of metastatic skin cancer with increased incidence over the past

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef680534de1132fb18a0ee2a6883ff3
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22701695/?tool=EBI