Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jorge A. Trejo-Lopez"'
Autor:
Grace M. Lloyd, Jorge A. Trejo-Lopez, Yuxing Xia, Karen N. McFarland, Sarah J. Lincoln, Nilüfer Ertekin-Taner, Benoit I. Giasson, Anthony T. Yachnis, Stefan Prokop
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-9 (2020)
Abstract The discovery of mutations associated with familial forms of Alzheimer’s disease (AD), has brought imperative insights into basic mechanisms of disease pathogenesis and progression and has allowed researchers to create animal models that a
Externí odkaz:
https://doaj.org/article/6c787f0501c440fe8c86864b1fb534c4
Autor:
Jess-Karan S. Dhillon, Jorge A. Trejo-Lopez, Cara Riffe, Yona Levites, Amanda N. Sacino, David R. Borchelt, Anthony Y. Yachnis, Benoit I. Giasson
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central nervous system (CNS) inoculation studies using either in vitro polymerized
Externí odkaz:
https://doaj.org/article/a3ea49b96b3e4f80980fb45dd667e57c
Publikováno v:
Neurology. 100:927-931
Autor:
Arenn F. Carlos, Hiroaki Sekiya, Shunsuke Koga, Nha Trang Thu Pham, Farwa Ali, Hugo Botha, Heather M. Clark, Elizabeth A. Coon, Val Lowe, J. Eric Ahlskog, Jorge A. Trejo-Lopez, Dennis W. Dickson, Jennifer L. Whitwell, Keith A. Josephs
Publikováno v:
Parkinsonism Relat Disord
INTRODUCTION: Multiple system atrophy (MSA) typically presents with parkinsonism, ataxia and/or autonomic dysfunction. Occasionally, clinically atypical (ca-MSA) cases masquerade as progressive supranuclear palsy (PSP). We aimed to investigate whethe
Autor:
Jorge A, Trejo-Lopez, Corinne E, Praska, Cinthya, Zepeda Mendoza, Thomas M, Kollmeyer, Aditya, Raghunathan, Caterina, Giannini, Rachael A, Vaubel, Aivi, Nguyen, Mark E, Jentoft, Kliment, Donev, Gang, Zheng, Margaret A, DiGuardo, Benjamin R, Kipp, Robert B, Jenkins, Cristiane M, Ida
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 82:93-95
Autor:
David D. Fuller, Victoria E. Bindi, Anthony T. Yachnis, Michael D. Sunshine, Jorge A. Trejo-Lopez, Barbara K. Smith, Barry J. Byrne, Sabhya Rana
Publikováno v:
J Neurophysiol
Pompe disease (PD) is a neuromuscular disorder caused by a mutation in the acid alpha-glucosidase (GAA) gene. Patients with late-onset PD retain some GAA activity and present symptoms later in life, with fatality mainly associated with respiratory fa
Autor:
Cara J. Riffe, Benoit I. Giasson, Anthony T. Yachnis, Zachary A. Sorrentino, Jorge A. Trejo-Lopez, Stefan Prokop, Dennis W. Dickson
Publikováno v:
J Neuropathol Exp Neurol
Human neurodegenerative diseases can be characterized as disorders of protein aggregation. As a key player in cellular autophagy and the ubiquitin proteasome system, p62 may represent an effective immunohistochemical target, as well as mechanistic op
Publikováno v:
Neurotherapeutics
The key pathological hallmarks—extracellular plaques and intracellular neurofibrillary tangles (NFT)—described by Alois Alzheimer in his seminal 1907 article are still central to the postmortem diagnosis of Alzheimer’s disease (AD), but major a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac7caee61fd51f8368d6900416e47d9
https://europepmc.org/articles/PMC9130398/
https://europepmc.org/articles/PMC9130398/
Publikováno v:
Clinical Infectious Diseases. 75:356-357
Autor:
Kathryn L. Eschbacher, Derek R. Johnson, Aditya Shah, Audrey N. Schuetz, Jorge A. Trejo-Lopez, Lorenzo Rinaldo, Jeffrey Huang, Kyriakos Chatzopoulos, Nancy L. Wengenack, Amber A. Milone, Pooja Gurram, Ian F. Parney
Publikováno v:
Brain Pathology. 32