Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jorge A. Sierra-Fonseca"'
Autor:
Jameel N. Hamdan, Jorge A. Sierra-Fonseca, Rodolfo J. Flores, Sigifredo Saucedo, Manuel Miranda-Arango, Laura E. O’Dell, Kristin L. Gosselink
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Early-life adversity (ELA) can induce persistent neurological changes and increase the risk for developing affective or substance use disorders. Disruptions to the reward circuitry of the brain and pathways serving motivation and emotion have been im
Externí odkaz:
https://doaj.org/article/1e9628ef94b34f1e90a0ce0cfd2aa376
Autor:
Francisco J. Flores-Ramirez, Anapaula Themann, Jorge A. Sierra-Fonseca, Israel Garcia-Carachure, Samuel A. Castillo, Minerva Rodriguez, Omar Lira, Joshua Preciado-Piña, Brandon L. Warren, Alfred J. Robison, Sergio D. Iñiguez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The objective of this study was to evaluate whether juvenile fluoxetine (FLX) exposure induces long-term changes in baseline responses to anxiety-inducing environments, and if so, whether its re-exposure in adulthood would ameliorate this an
Externí odkaz:
https://doaj.org/article/80c4ded134d041aa88cdd77b4d2e9863
Autor:
Jorge A. Sierra-Fonseca, Jameel N. Hamdan, Alexis A. Cohen, Sonia M. Cardenas, Sigifredo Saucedo, Gabriel A. Lodoza, Kristin L. Gosselink
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Exposure to early-life stress (ELS) can persistently modify neuronal circuits and functions, and contribute to the expression of misfolded and aggregated proteins that are hallmarks of several neurodegenerative diseases. The healthy brain is able to
Externí odkaz:
https://doaj.org/article/3fd803ff74f3489eb294084ee741c8bd
Publikováno v:
Neurobiology of Stress, Vol 9, Iss , Pp 105-112 (2018)
Neurodegenerative diseases are characterized by an irreversible and progressive loss of neuronal structure and function. While many alterations to normal cellular processes occur during neurodegeneration, a pathological accumulation of aggregated pro
Externí odkaz:
https://doaj.org/article/f18fffd56f064ba987d9cb34a03c0d27
Autor:
Javier Vargas-Medrano, Jorge A. Sierra-Fonseca, Manuel Arellano-Carrillo, Fernando Plenge-Tellechea
Publikováno v:
Tecnociencia Chihuahua, Vol 5, Iss 3 (2020)
Abstract The extensive use of pesticides can cause many human health problems. However, the effects of pesticides on a biochemical level are still poorly understood. In this study we analyzed the effect of different pesticides on the plasma membra
Externí odkaz:
https://doaj.org/article/184f6fb2a26b4307b11388ab4608ea4e
Autor:
Manuel Arellano-Carrillo, Javier Vargas-Medrano, Jorge A. Sierra-Fonseca, Fernando Plenge-Tellechea
Publikováno v:
Tecnociencia Chihuahua, Vol 6, Iss 2 (2020)
Los plaguicidas son un amplio grupo de sustancias heterogéneas que producen un beneficio mediante la disminución de vectores que trasmiten enfermedades, y en el control de plagas que afectan la producción agrícola. En el presente trabajo estu
Externí odkaz:
https://doaj.org/article/5e1e1e2aaeba45828dbf31bb8fe06bf9
Autor:
Jorge A. Sierra-Fonseca, Lyonna F. Parise, Francisco J. Flores-Ramirez, Eden H. Robles, Israel Garcia-Carachure, Sergio D. Iñiguez
Publikováno v:
Chronic Stress, Vol 3 (2019)
Background Anxiety disorders are the most common neuropathologies worldwide, but the precise neuronal mechanisms that underlie these disorders remain unknown. The hippocampus plays a role in mediating anxiety-related responses, which can be modeled i
Externí odkaz:
https://doaj.org/article/a4df847fe7e14be7a01b5f377047b809
Autor:
Ivan E. Flores, Jorge A. Sierra-Fonseca, Olinamyr Davalos, Luis A. Saenz, Maria M. Castellanos, Jaidee K. Zavala, Kristin L. Gosselink
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background Prostate cancer is a major contributor to mortality worldwide, and significant efforts are being undertaken to decipher specific cellular and molecular pathways underlying the disease. Chronic stress is known to suppress reproduct
Externí odkaz:
https://doaj.org/article/cd148ca1de2042c4b4e0ab3c7df59665
Publikováno v:
Frontiers in Behavioral Neuroscience. 16
Autor:
Javier Vargas-Medrano, Sergio D. Iñiguez, Minerva Rodriguez, Anapaula Themann, Francisco J Flores-Ramirez, Bharathi S. Gadad, Omar Lira, Jorge A. Sierra-Fonseca
Publikováno v:
J Alzheimers Dis
Background: Fluoxetine (FLX) represents the antidepressant of choice for the management of pediatric mood-related illnesses. Accumulating preclinical evidence suggests that ontogenic FLX exposure leads to deregulated affect-related phenotypes in adul