Zobrazeno 1 - 10
of 1 254
pro vyhledávání: '"Jorge A. Reis"'
Autor:
Mariana Ferreira Cardoso, Luís Carvalho Lourenço, Margarida Antunes, Joana Carvalho e Branco, Liliana Santos, Alexandra Martins, Jorge A. Reis
Publikováno v:
GE: Portuguese Journal of Gastroenterology, Pp 1-5 (2018)
Von Willebrand disease (vWD) is the most prevalent hereditary bleeding disorder, affecting 0.6–1.3% of the population. While gastrointestinal bleeding from angiodysplasia is a well-known complication of vWD, the same is not true for Dieulafoy’s l
Externí odkaz:
https://doaj.org/article/24b98808e0764e08ac18fe3901b5dad6
Autor:
Joana C. Branco, Mariana F. Cardoso, Vera Anapaz, Luís Carvalho Lourenço, Ana Maria Oliveira, Catarina Graça Rodrigues, Liliana Santos, Jorge A. Reis
Publikováno v:
GE: Portuguese Journal of Gastroenterology, Pp 1-8 (2018)
Background and Aims: Vitamin D deficiency is more common in inflammatory bowel disease (IBD) patients than in the general population. However, there are conflicting data about predictive factors of vitamin D deficiency and its potential association w
Externí odkaz:
https://doaj.org/article/4828f5a309494257b409ed7f86af0a24
Publikováno v:
GE: Portuguese Journal of Gastroenterology, Pp 1-3 (2019)
Breast cancer is the most common tumour in women. Only 5–15% of breast cancer patients have distant metastases at diagnosis. Here we describe the case of a previously healthy 43-year-old woman with nausea, postprandial epigastric pain, and constipa
Externí odkaz:
https://doaj.org/article/a7d88ae1e36747fb94d50f36daccb0d7
Publikováno v:
Molecular Oncology, Vol 18, Iss 11, Pp 2607-2611 (2024)
The incorporation of novel therapeutic agents such as antibody‐drug conjugates, radio‐conjugates, T‐cell engagers, and chimeric antigen receptor cell therapies represents a paradigm shift in oncology. Cell‐surface target quantification, quant
Externí odkaz:
https://doaj.org/article/9d347ab686e440cd84951119568cca8f
Autor:
Chiara Maria Lavinia Loeffler, Omar S. M. El Nahhas, Hannah Sophie Muti, Zunamys I. Carrero, Tobias Seibel, Marko van Treeck, Didem Cifci, Marco Gustav, Kevin Bretz, Nadine T. Gaisa, Kjong-Van Lehmann, Alexandra Leary, Pier Selenica, Jorge S. Reis-Filho, Nadina Ortiz-Bruechle, Jakob Nikolas Kather
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Homologous recombination deficiency (HRD) is recognized as a pan-cancer predictive biomarker that potentially indicates who could benefit from treatment with PARP inhibitors (PARPi). Despite its clinical significance, HRD testing
Externí odkaz:
https://doaj.org/article/003303862b20434e84941368c6c014a7
Autor:
Manisha Jalan, Aman Sharma, Xin Pei, Nils Weinhold, Erika S. Buechelmaier, Yingjie Zhu, Sana Ahmed-Seghir, Abhirami Ratnakumar, Melody Di Bona, Niamh McDermott, Joan Gomez-Aguilar, Kyrie S. Anderson, Charlotte K. Y. Ng, Pier Selenica, Samuel F. Bakhoum, Jorge S. Reis-Filho, Nadeem Riaz, Simon N. Powell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Collisions of the transcription and replication machineries on the same DNA strand can pose a significant threat to genomic stability. These collisions occur in part due to the formation of RNA-DNA hybrids termed R-loops, in which a newly tr
Externí odkaz:
https://doaj.org/article/7cd61270c6534754a1bbd7203bce046c
Publikováno v:
GE: Portuguese Journal of Gastroenterology, Pp 1-2 (2019)
Externí odkaz:
https://doaj.org/article/f831250d66474cffa7847d32f5acf5cc
Autor:
Joana C. Branco, Mariana F. Cardoso, Luís Carvalho Lourenço, Liliana Santos, David Valadas Horta, Élia Coimbra, Jorge A. Reis
Publikováno v:
GE: Portuguese Journal of Gastroenterology (2017)
Introduction: Walled-off necrosis (WON) is a potentially lethal late complication of acute pancreatitis (AP) and occurs in less than 10% of AP cases. It can be located in or outside the pancreas. When infected, the mortality rate increases and can re
Externí odkaz:
https://doaj.org/article/6511364b31a8407aa909a9956c0bacc4
Autor:
Yingjie Zhu, Xin Pei, Ardijana Novaj, Jeremy Setton, Daniel Bronder, Fatemeh Derakhshan, Pier Selenica, Niamh McDermott, Mehmet Orman, Sarina Plum, Shyamal Subramanyan, Sara H. Braverman, Biko McMillan, Sonali Sinha, Jennifer Ma, Andrea Gazzo, Atif Khan, Samuel Bakhoum, Simon N. Powell, Jorge S. Reis-Filho, Nadeem Riaz
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Pathogenic BRCA1 or BRCA2 germline mutations contribute to hereditary breast, ovarian, prostate, and pancreatic cancer. Paradoxically, bi-allelic inactivation of BRCA1 or BRCA2 (bBRCA1/2) is embryonically lethal and decreases cell
Externí odkaz:
https://doaj.org/article/a99e307f304a411b854e096a6e780f20
Autor:
Steffi Oesterreich, Leigh Pate, Adrian V. Lee, Fangyuan Chen, Rachel C. Jankowitz, Rita Mukhtar, Otto Metzger, Matthew J. Sikora, Christopher I. Li, Christos Sotiriou, Osama S. Shah, Thijs Koorman, Gary Ulaner, Jorge S. Reis-Filho, Nancy M. Davidson, Karen Van Baelen, Laurie Hutcheson, Siobhan Freeney, Flora Migyanka, Claire Turner, Patrick Derksen, Todd Bear, Christine Desmedt
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract There is growing awareness of the unique etiology, biology, and clinical presentation of invasive lobular breast cancer (ILC), but additional research is needed to ensure translation of findings into management and treatment guidelines. We c
Externí odkaz:
https://doaj.org/article/674206de519c4c9a91765a34839d5098