Phage-inducible chromosomal minimalist islands (PICMIs), a novel family of small marine satellites of virulent phages

Autor: Rubén Barcia-Cruz, David Goudenège, Jorge A. Moura de Sousa, Damien Piel, Martial Marbouty, Eduardo P. C. Rocha, Frédérique Le Roux

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Abstract Phage satellites are bacterial genetic elements that co-opt phage machinery for their own dissemination. Here we identify a family of satellites, named Phage-Inducible Chromosomal Minimalist Islands (PICMIs), that are broadly distributed in

Externí odkaz: https://doaj.org/article/847e2ff338e240dda1158faf1f5ade23

Phylogenetic background and habitat drive the genetic diversification of Escherichia coli.

Autor: Marie Touchon, Amandine Perrin, Jorge André Moura de Sousa, Belinda Vangchhia, Samantha Burn, Claire L O'Brien, Erick Denamur, David Gordon, Eduardo Pc Rocha

Publikováno v: PLoS Genetics, Vol 16, Iss 6, p e1008866 (2020)

Escherichia coli is mostly a commensal of birds and mammals, including humans, where it can act as an opportunistic pathogen. It is also found in water and sediments. We investigated the phylogeny, genetic diversification, and habitat-association of

Externí odkaz: https://doaj.org/article/f03f2d0f039840ebbf546e849ba07704

Genetic exchanges are more frequent in bacteria encoding capsules.

Autor: Olaya Rendueles, Jorge A Moura de Sousa, Aude Bernheim, Marie Touchon, Eduardo P C Rocha

Publikováno v: PLoS Genetics, Vol 14, Iss 12, p e1007862 (2018)

Capsules allow bacteria to colonize novel environments, to withstand numerous stresses, and to resist antibiotics. Yet, even though genetic exchanges with other cells should be adaptive under such circumstances, it has been suggested that capsules lo

Externí odkaz: https://doaj.org/article/4b3a78f9f0ef4a2c8c3fecde56c1368c

Causes and Consequences of Bacteriophage Diversification via Genetic Exchanges across Lifestyles and Bacterial Taxa

Autor: Eugen Pfeifer, Jorge A. Moura de Sousa, Marie Touchon, Eduardo P. C. Rocha

Publikováno v: Molecular Biology and Evolution
Molecular Biology and Evolution, Oxford University Press (OUP), 2021, 38 (6), pp.2497-2512. ⟨10.1093/molbev/msab044⟩
Molecular Biology and Evolution, 2021, 38 (6), pp.2497-2512. ⟨10.1093/molbev/msab044⟩

Bacteriophages (phages) evolve rapidly by acquiring genes from other phages leading to mosaic genomes. Here, we identify numerous genetic transfers between distantly related phages and aim at understanding their frequency, consequences and the condit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92d5f38c447cf8bf24ec885c7a70bfe
http://europepmc.org/articles/PMC8136500

Environmental structure drives resistance to phages and antibiotics during phage therapy and to invading lysogens during colonisation

Autor: Jorge A. Moura de Sousa, Eduardo P. C. Rocha

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports, 2019, 9 (1), pp.3149. ⟨10.1038/s41598-019-39773-3⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.3149. ⟨10.1038/s41598-019-39773-3⟩

Microbial communities are shaped by bacteriophages through predation and lysogeny. A better understanding of the interactions between these processes across different types of environments is key to elucidate how phages mediate microbial competition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b05add35db1085039d9028901a860a
http://link.springer.com/article/10.1038/s41598-019-39773-3