Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jorge A Iñiguez Lluhí"'
Autor:
Richard R. Neubig, Sofia D. Merajver, Jorge A. Iñiguez-Lluhí, Mei Wu, Qin Wang, Susan M. Wade, Chris R. Evelyn
Lysophosphatidic acid receptors stimulate a Gα12/13/RhoA-dependent gene transcription program involving the serum response factor (SRF) and its coactivator and oncogene, megakaryoblastic leukemia 1 (MKL1). Inhibitors of this pathway could serve as u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434ab8fcd3429745e1f9e1aa5ec3c02e
https://doi.org/10.1158/1535-7163.c.6532116.v1
https://doi.org/10.1158/1535-7163.c.6532116.v1
Autor:
Jorge A. Iñiguez-Lluhí
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
Journal of Cell Science
Cilia are evolutionarily conserved organelles found on many mammalian cell types, including neuronal populations. Although neuronal cilia, including those on olfactory sensory neurons (OSNs), are often delineated by localization of adenylyl cyclase 3
Autor:
Richard C. McEachin, Jason P. Chua, Diane E. Merry, Heather L. Montie, Sarmistha Mukherjee, Elisa Giorgetti, Jake Higgins, Diane M. Robins, Jorge A. Iñiguez-Lluhí, Satya L. Reddy, Andrew P. Lieberman, Zhigang Yu
Publikováno v:
Journal of Clinical Investigation. 125:831-845
Expansion of the polyglutamine (polyQ) tract within the androgen receptor (AR) causes neuromuscular degeneration in individuals with spinobulbar muscular atrophy (SBMA). PolyQ AR has diminished transcriptional function and exhibits ligand-dependent p
Publikováno v:
Advances in experimental medicine and biology. 963
Recently, a role for SUMO modification outside of the nucleus has emerged. Although the number of extranuclear proteins known to be sumoylated is comparatively small, ion channels represent one important new class of these proteins. Ion channels are
Publikováno v:
SUMO Regulation of Cellular Processes ISBN: 9783319500430
Recently, a role for SUMO modification outside of the nucleus has emerged. Although the number of extranuclear proteins known to be sumoylated is comparatively small, ion channels represent one important new class of these proteins. Ion channels are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d651894bbbabb804cce85e1d25ad21f3
https://doi.org/10.1007/978-3-319-50044-7_8
https://doi.org/10.1007/978-3-319-50044-7_8
Autor:
Eduardo Arzt, Jimena Druker, Jorge A. Iñiguez-Lluhí, Florian Holsboer, Ana C. Liberman, María Antunica-Noguerol, Juan Gerez, Marcelo Paez-Pereda, Theo Rein
Publikováno v:
Molecular and Cellular Biology. 33:2116-2127
Glucocorticoid receptor (GR) activity is modulated by posttranslational modifications, including phosphorylation, ubiquitination, and SUMOylation. The GR has three SUMOylation sites: lysine 297 (K297) and K313 in the N-terminal domain (NTD) and K721
Publikováno v:
Journal of Biological Chemistry. 287:31195-31206
The androgen receptor (AR) mediates the effects of male sexual hormones on development and physiology. Alterations in AR function are central to reproductive disorders, prostate cancer, and Kennedy disease. AR activity is influenced by post-translati
Autor:
Jorge A. Iñiguez-Lluhí, Theodora E. Danciu, Malcolm Whitman, Sergey Chupreta, Osvaldo Cruz, Jennifer E. Fox
Publikováno v:
Journal of Biological Chemistry. 287:18318-18329
FOXC1 and FOXC2 are forkhead transcription factors that play essential roles during development and physiology. Despite their critical role, the mechanisms that regulate the function of these factors remain poorly understood. We have identified conse
Autor:
Lian Zhang, Jorge A. Iñiguez-Lluhí, Arun Anantharam, Jeremy C. McIntyre, Cynthia J. L. Carruthers, Paul M. Jenkins, Jeffrey R. Martens, Tom K. Kerppola, Eileen D. Vesely, Kristin L. Arendt, Michael A. Sutton, Ronald W. Holz
Publikováno v:
The Journal of Neuroscience. 31:13224-13235
Voltage-gated potassium (Kv) channels are critical for neuronal excitability and are targeted to specific subcellular compartments to carry out their unique functions. While it is widely believed that Kv channels exist as heteromeric complexes in neu