Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Jorge A, Piedrahita"'
Autor:
Amanda B. T. Hill, Yanet M. Murphy, Kathryn M. Polkoff, Laura Edwards, Derek M. Walker, Adele Moatti, Alon Greenbaum, Jorge A. Piedrahita
Publikováno v:
Frontiers in Genome Editing, Vol 6 (2024)
Recent advancements in genome editing techniques, notably CRISPR-Cas9 and TALENs, have marked a transformative era in biomedical research, significantly enhancing our understanding of disease mechanisms and helping develop novel therapies. These tech
Externí odkaz:
https://doaj.org/article/5275e6c26dd74e15a4a927b31165176a
A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humans
Autor:
Wencheng Zhang, Xicheng Wang, Giacomo Lanzoni, Eliane Wauthier, Sean Simpson, Jennifer Ashley Ezzell, Amanda Allen, Carolyn Suitt, Jonah Krolik, Alexander Jhirad, Juan Dominguez-Bendala, Vincenzo Cardinale, Domenico Alvaro, Diletta Overi, Eugenio Gaudio, Praveen Sethupathy, Guido Carpino, Christopher Adin, Jorge A Piedrahita, Kyle Mathews, Zhiying He, Lola McAdams Reid
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-20 (2023)
Abstract A network of co-hepato/pancreatic stem/progenitors exists in pigs and humans in Brunner’s Glands in the submucosa of the duodenum, in peribiliary glands (PBGs) of intrahepatic and extrahepatic biliary trees, and in pancreatic duct glands (
Externí odkaz:
https://doaj.org/article/518939a17b4a4764b3b4103fbad6b25f
Autor:
Trevor J. Gonzalez, Katherine E. Simon, Leo O. Blondel, Marco M. Fanous, Angela L. Roger, Maribel Santiago Maysonet, Garth W. Devlin, Timothy J. Smith, Daniel K. Oh, L. Patrick Havlik, Ruth M. Castellanos Rivera, Jorge A. Piedrahita, Mai K. ElMallah, Charles A. Gersbach, Aravind Asokan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Recombinant adeno-associated viral (AAV) vectors are a promising gene delivery platform, but ongoing clinical trials continue to highlight a relatively narrow therapeutic window. Effective clinical translation is confounded, at least in part
Externí odkaz:
https://doaj.org/article/d9d15ee20e5e46a9b86982294d7e7093
Autor:
Kathryn M. Polkoff, Nithin K. Gupta, Adrian J. Green, Yanet Murphy, Jaewook Chung, Katherine L. Gleason, Sean G. Simpson, Derek M. Walker, Bruce Collins, Jorge A. Piedrahita
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Hair follicle stem cells are key for driving growth and homeostasis of the hair follicle niche, have remarkable regenerative capacity throughout hair cycling, and display fate plasticity during cutaneous wound healing. Due to the need for a
Externí odkaz:
https://doaj.org/article/ef035f66ea5749d5ab578b03eb7821c4
Autor:
Renan B. Sper, Jessica Proctor, Odessa Lascina, Ling Guo, Kathryn Polkoff, Tobias Kaeser, Sean Simpson, Luke Borst, Katherine Gleason, Xia Zhang, Bruce Collins, Yanet Murphy, Jeffrey L. Platt, Jorge A. Piedrahita
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Mice with severe combined immunodeficiency are commonly used as hosts of human cells. Size, longevity, and physiology, however, limit the extent to which immunodeficient mice can model human systems. To address these limitations, we generated RAG2−
Externí odkaz:
https://doaj.org/article/7a3922f25e6c4f00a302e70e74c3ba8c
Autor:
Wencheng Zhang, Xicheng Wang, Giacomo Lanzoni, Eliane Wauthier, Sean Simpson, Jennifer Ashley Ezzell, Amanda Allen, Carolyn Suitt, Jonah Krolik, Alexander Jhirad, Juan Dominguez-Bendala, Vincenzo Cardinale, Domenico Alvaro, Diletta Overi, Eugenio Gaudio, Praveen Sethupathy, Guido Carpino, Christopher Adin, Jorge A Piedrahita, Kyle Mathews, Zhiying He, Lola McAdams Reid
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/9e69a59f0dbf47958dec6e7cced3d56d
Autor:
Adele Moatti, Chen Li, Sasank Sivadanam, Yuheng Cai, James Ranta, Jorge A. Piedrahita, Alan G. Cheng, Frances S. Ligler, Alon Greenbaum
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104695- (2022)
Summary: Over 11% of the world’s population experience hearing loss. Although there are promising studies to restore hearing in rodent models, the size, ontogeny, genetics, and frequency range of hearing of most rodents’ cochlea do not match that
Externí odkaz:
https://doaj.org/article/3f08679200f540b29ba454ca1c49df1f
Publikováno v:
Tissue engineering. Part A. 28(19-20)
Current cellular hydrogel-based skin grafts composed of human dermal fibroblasts and a hydrogel scaffold tend to minimize contraction of full-thickness skin wounds and support skin regeneration. However, there has been no comparison between the sourc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5124b70867861e2724398d7f1c3722ea
https://pubmed.ncbi.nlm.nih.gov/35925753
https://pubmed.ncbi.nlm.nih.gov/35925753
Autor:
Stephanie G Cone, Hope E Piercy, Emily P Lambeth, Hongyu Ru, Jorge A Piedrahita, Jeffrey T Spang, Lynn A Fordham, Matthew B Fisher
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0219637 (2019)
Prior studies have analyzed growth of musculoskeletal tissues between species or across body segments; however, little research has assessed the differences in similar tissues within a single joint. Here we studied changes in the length and cross-sec
Externí odkaz:
https://doaj.org/article/fb7768aee5d644daa3d4875d9366edc4
Autor:
Cecilia R. Schaaf, Kathryn M. Polkoff, Amber Carter, Amy S. Stewart, Breanna Sheahan, John Freund, Joshua Ginzel, Joshua C. Snyder, Jatin Roper, Jorge A. Piedrahita, Liara M. Gonzalez
Publikováno v:
The FASEB Journal. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0e9ca2160b453ed758af266220b87cb
https://doi.org/10.1096/fj.202300223r
https://doi.org/10.1096/fj.202300223r