Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jorg Stetefeld"'
Autor:
Emmanuel O Ariyo, Evan P Booy, Trushar R Patel, Edis Dzananovic, Ewan K McRae, Markus Meier, Kevin McEleney, Jorg Stetefeld, Sean A McKenna
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144510 (2015)
Nucleic acids rich in guanine are able to fold into unique structures known as G-quadruplexes. G-quadruplexes consist of four tracts of guanylates arranged in parallel or antiparallel strands that are aligned in stacked G-quartet planes. The structur
Externí odkaz:
https://doaj.org/article/09bafcf3bcda4fa283619b50b11332a5
Autor:
Markus Meier, Monika Gupta, Serife Akgül, Matthew McDougall, Thomas Imhof, Denise Nikodemus, Raphael Reuten, Aniel Moya-Torres, Vu To, Fraser Ferens, Fabian Heide, Gay Pauline Padilla-Meier, Philipp Kukura, Wenming Huang, Birgit Gerisch, Matthias Mörgelin, Kate Poole, Adam Antebi, Manuel Koch, Jörg Stetefeld
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
In this work, the authors report that heparin oligosaccharides have a significant impact on the highly dynamic behaviour of netrin-1 by inducing hierarchical and distinct super assemblies leading to unique, yet unknown netrin-1 filament formation.
Externí odkaz:
https://doaj.org/article/a17b613185c64a9eb8c69d8aacb59de3
Autor:
Nicolai B. Grether, Felix Napravnik, Thomas Imhof, Reinhold P. Linke, Jan H. Bräsen, Jessica Schmitz, Maike Dohrn, Christian Schneider, Martin K. R. Svačina, Jörg Stetefeld, Manuel Koch, Helmar C. Lehmann
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 8, Pp 1252-1263 (2022)
Abstract Objective Hereditary transthyretin‐mediated amyloidosis is a treatable condition caused by amyloidogenic variants in the transthyretin‐gene resulting in severe peripheral neuropathy or cardiomyopathy. Only about a third of over 130 known
Externí odkaz:
https://doaj.org/article/9256e40912be45d381aff1bc160d6894
Publikováno v:
The FASEB Journal. 28
Prohibitins (PHB) are highly conserved and ubiquitously expressed proteins in eukaryotic cells. The prohibitin family exist in two isoforms PHB1 (also known as BAP32) and PHB2 ( also known as BAP37 and REA). The PHB1 and PHB2 together form large ring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a121d6c0d47f9738f78973cd1269dca8
https://doi.org/10.1096/fasebj.28.1_supplement.603.1
https://doi.org/10.1096/fasebj.28.1_supplement.603.1
Autor:
Fabian Heide, Matthew McDougall, Candice Harder-Viddal, Roy Roshko, David Davidson, Jiandong Wu, Camila Aprosoff, Aniel Moya-Torres, Francis Lin, Jörg Stetefeld
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Boron neutron capture therapy (BNCT) is a two-step therapeutic process that utilizes Boron-10 in combination with low energy neutrons to effectively eliminate targeted cells. This therapy is primarily used for difficult to treat head and nec
Externí odkaz:
https://doaj.org/article/d1a8ba6943f14b2d81e7448fdac0e9ec
Autor:
Berenice Ziegler, Irene Yiallouros, Benjamin Trageser, Sumit Kumar, Moritz Mercker, Svenja Kling, Maike Fath, Uwe Warnken, Martina Schnölzer, Thomas W. Holstein, Markus Hartl, Anna Marciniak-Czochra, Jörg Stetefeld, Walter Stöcker, Suat Özbek
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-22 (2021)
Abstract Background The Hydra head organizer acts as a signaling center that initiates and maintains the primary body axis in steady state polyps and during budding or regeneration. Wnt/beta-Catenin signaling functions as a primary cue controlling th
Externí odkaz:
https://doaj.org/article/5576cb9a33f145bf9dc87ff3ebb7a844
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 471 (2023)
Heparan sulfate is a crucial extracellular matrix component that organizes structural features and functional protein processes. This occurs through the formation of protein–heparan sulfate assemblies around cell surfaces, which allow for the delib
Externí odkaz:
https://doaj.org/article/a5a0a6275c194f14a573f1c51518ad67
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The voltage-dependent anion-selective channel (VDAC) is a porin in the mitochondrial outer membrane (MOM). Unlike bacterial porins, several mitochondrial β-barrels comprise an odd number of β-strands, as is the case for the 19-β-stranded VDAC. Pre
Externí odkaz:
https://doaj.org/article/487d3306d0aa43f3a9330dc4c8de2a82
Autor:
Fabian Heide, Jörg Stetefeld
Publikováno v:
Nanomaterials, Vol 12, Iss 22, p 4080 (2022)
Protein nanotubes offer unique properties to the materials science field that allow them to fulfill various functions in drug delivery, biosensors and energy storage. Protein nanotubes are chemically diverse, modular, biodegradable and nontoxic. Furt
Externí odkaz:
https://doaj.org/article/536d790a9f614101abd5b6b39d39d0cd
Publikováno v:
ACS Omega, Vol 2, Iss 8, Pp 4612-4620 (2017)
Externí odkaz:
https://doaj.org/article/0cc5537f033f421aaa6af0509b9fc760