Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jorg J. A. Calis"'
Autor:
Maurice J. H. van Haaren, Levina Bertina Steller, Sebastiaan J. Vastert, Jorg J. A. Calis, Jorg van Loosdregt
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8123 (2024)
Immune responses demand the rapid and precise regulation of gene protein expression. Splicing is a crucial step in this process; ~95% of protein-coding gene transcripts are spliced during mRNA maturation. Alternative splicing allows for distinct func
Externí odkaz:
https://doaj.org/article/12f3e8924c3e48c8800327f80b4531b3
Autor:
Michele F. Buono, Ernest Diez Benavente, Lotte Slenders, Daisey Methorst, Daniëlle Tessels, Eloi Mili, Roxy Finger, Daniek Kapteijn, Mark Daniels, Noortje A. M. van den Dungen, Jorg J. A. Calis, Barend M. Mol, Gert J. de Borst, Dominique P. V. de Kleijn, Gerard Pasterkamp, Hester M. den Ruijter, Michal Mokry
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background Plaque myofibroblasts are critical players in the initiation and advancement of atherosclerotic disease. They are involved in the production of extracellular matrix, the formation of the fibrous cap, and the underlying lipidic core via mod
Externí odkaz:
https://doaj.org/article/cd25f14d033d48ac9391413aa12d5e81
Autor:
Ellen C. N. van Vroonhoven, Lucas W. Picavet, Rianne C. Scholman, Noortje A. M. van den Dungen, Michal Mokry, Anouk Evers, Robert J. Lebbink, Jorg J. A. Calis, Sebastiaan J. Vastert, Jorg van Loosdregt
Publikováno v:
Biology, Vol 12, Iss 7, p 1004 (2023)
T cell activation is a highly regulated process, modulated via the expression of various immune regulatory proteins including cytokines, surface receptors and co-stimulatory proteins. N6-methyladenosine (m6A) is an RNA modification that can directly
Externí odkaz:
https://doaj.org/article/e018e45d2b0a4df48705f4e586c2bf9d
Autor:
Kirsten Geneugelijk, Kirsten A. Thus, Hanneke W. M. van Deutekom, Jorg J. A. Calis, Eric Borst, Can Keşmir, Machteld Oudshoorn, Bronno van der Holt, Ellen Meijer, Sacha Zeerleder, Marco R. de Groot, Peter A. von dem Borne, Nicolaas Schaap, Jan Cornelissen, Jürgen Kuball, Eric Spierings
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
HLA-mismatches in hematopoietic stem-cell transplantation are associated with an impaired overall survival (OS). The aim of this study is to explore whether the Predicted Indirectly ReCognizable HLA-Epitopes (PIRCHE) algorithm can be used to identify
Externí odkaz:
https://doaj.org/article/04efaf33c183496ba8c5a1597d27ee0a
Autor:
Michele F. Buono, Ernest Diez Benavente, Lotte Slenders, Daisey Methorst, Daniёlle Tessels, Eloi Mili, Roxy Finger, Daniek Kapteijn, Mark Daniels, Noortje A. M. van den Dungen, Jorg J. A. Calis, Barend M. Mol, Gert J. de Borst, Dominique P. V. de Kleijn, Gerard Pasterkamp, Hester M. den Ruijter, Michal Mokry
Plaque smooth muscle cells are critical players in the initiation and advancement of atherosclerotic disease. They produce extracellular matrix (ECM) components, which play a role in lesion progression and stabilization. Despite clear phenotypic diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de2364f8e54aaf3658a4b731398f1164
https://doi.org/10.1101/2023.02.09.527800
https://doi.org/10.1101/2023.02.09.527800
Autor:
Magdalena Harakalova, Benjamin Meder, Philippe Charron, Manuel Gómez-Bueno, Jorg J. A. Calis, François Cambien, David-Alexandre Trégouët, Maurizia Grasso, Steven McGinn, Uwe Völker, Thomas Meitinger, Stefan Weiss, L. Duboscq-Bidot, Richard Dorent, Vera Regitz-Zagrosek, Folkert W. Asselbergs, Hélène Blanché, Olivier Dubourg, Patrick Lacolley, Pierre Boutouyrie, Delphine Bacq-Daian, Vincent Fontaine, Volker Ruppert, Marine Germain, K Lehnert, Jean-Noël Trochu, Stuart A. Cook, Angélique Curjol, Brendan J. Keating, Ibticem Raji, Anne Boland, J. Erdmann, Michael Morley, Jean-François Aupetit, Paloma Remior, Luigi Tavazzi, Gérard Roizès, Michal Mokry, Konstantin Strauch, Richard Isnard, Jean-Philippe Empana, Robert Olaso, Kenneth B. Marguiles, Zofia T. Bilińska, Stephan B. Felix, Marcus Dörr, Thomas P. Cappola, Stefan Blankenberg, Jan Haas, Céline Besse, Jean-François Deleuze, Christine E. Seidman, Christian Hengstenberg, Jessica van Setten, Hakon Hakonarson, Sanjay K Prasad, Daiane Hemerich, Pascal de Groote, Thomas Wichter, Alain van Mil, Michel Komajda, Renee Maas, Carole Proust, Declan P. O'Regan, Xavier Jouven, Ganapathi Varma Saripella, Georgios Kararigas, Eloisa Arbustini, Jin Li, Klaus Stark, Laurent Fauchier, Flavie Ader, Melanie Waldenberger, Martina Müller-Nurasyid, Eric Villard, Sophie Garnier
Publikováno v:
European heart journal, 42(20), 2000-2011. Oxford University Press
European Heart Journal
European Heart Journal, Oxford University Press (OUP): Policy B, 2021, ⟨10.1093/eurheartj/ehab030⟩
European Heart Journal, 2021, 42 (20), pp.2000-2011. ⟨10.1093/eurheartj/ehab030⟩
European Heart Journal
European Heart Journal, Oxford University Press (OUP): Policy B, 2021, ⟨10.1093/eurheartj/ehab030⟩
European Heart Journal, 2021, 42 (20), pp.2000-2011. ⟨10.1093/eurheartj/ehab030⟩
Aims Our objective was to better understand the genetic bases of dilated cardiomyopathy (DCM), a leading cause of systolic heart failure. Methods and results We conducted the largest genome-wide association study performed so far in DCM, with 2719 ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2fb4a5751c8873677e1b542fdd8c3a
https://pure.amc.nl/en/publications/genomewide-association-analysis-in-dilated-cardiomyopathy-reveals-two-new-players-in-systolic-heart-failure-on-chromosomes-3p251-and-22q1123(8df098a2-4e2b-436a-8594-9c6ed3e705d8).html
https://pure.amc.nl/en/publications/genomewide-association-analysis-in-dilated-cardiomyopathy-reveals-two-new-players-in-systolic-heart-failure-on-chromosomes-3p251-and-22q1123(8df098a2-4e2b-436a-8594-9c6ed3e705d8).html
Autor:
Jorg J A Calis, Matt Maybeno, Jason A Greenbaum, Daniela Weiskopf, Aruna D De Silva, Alessandro Sette, Can Keşmir, Bjoern Peters
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 10, p e1003266 (2013)
T-cells have to recognize peptides presented on MHC molecules to be activated and elicit their effector functions. Several studies demonstrate that some peptides are more immunogenic than others and therefore more likely to be T-cell epitopes. We set
Externí odkaz:
https://doaj.org/article/3a0516b610ee4236954bbc168fd25a74
Autor:
Peter van Tintelen, Aryan Vink, Ema Nagyova, Michal Mokry, Johannes M.I.H. Gho, Hester M. den Ruijter, Manon M. H. Huibers, Boudewijn M.T. Burgering, Mark Mercola, René van Es, Jorg J. A. Calis, Jan W. Buikema, Roel A. de Weger, Alain van Mil, Caroline Cheng, Renee G.C. Maas, Nicolaas de Jonge, Linda W. van Laake, Christian J.B. Snijders Blok, Joost P.G. Sluijter, Pieter A. Doevendans, Iris van Adrichem, Nico Lansu, Folkert W. Asselbergs, Ioannis Kararikes, Jiayi Pei, Shahrzad Sepehrkhouy, Frank G. van Steenbeek, Magdalena Harakalova, Noortje A.M. van den Dungen, Dries A.M. Feyen, Marianne C. Verhaar
BackgroundThe R14del mutation in the phospholamban (PLN) gene is associated with various types of cardiomyopathies and increases the risk of developing life-threatening ventricular arrhythmias. In this study, we focused on a homogeneous Dutch founder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483fec4b07ededb5ef4bee7d49d196f4
https://doi.org/10.1101/2020.11.30.402792
https://doi.org/10.1101/2020.11.30.402792
Autor:
Fieke Terstappen, Jaap A. Joles, Torsten Plösch, Bas B. van Rijn, Jorg J. A. Calis, Michal Mokry, A. Titia Lely, Nina D. Paauw
Publikováno v:
Clinical Epigenetics, 12(1):185. BioMed Central Ltd.
Clinical Epigenetics
Clinical Epigenetics, 12(1):185. BMC
Clinical Epigenetics
Clinical Epigenetics, 12(1):185. BMC
Background Fetal growth restriction (FGR) is associated with an increased susceptibility for various noncommunicable diseases in adulthood, including cardiovascular and renal disease. During FGR, reduced uteroplacental blood flow, oxygen and nutrient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8128765e4be28b3d16a73860c1cdb87e
https://pure.eur.nl/en/publications/87d91cb6-c1d9-4f53-9a70-3868f2d49a43
https://pure.eur.nl/en/publications/87d91cb6-c1d9-4f53-9a70-3868f2d49a43
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 3, p e1002412 (2012)
The cellular immune system screens peptides presented by host cells on MHC molecules to assess if the cells are infected. In this study we examined whether the presented peptides contain enough information for a proper self/nonself assessment by comp
Externí odkaz:
https://doaj.org/article/1c62f21f1be24df5888faeb93abf12c5